Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Director, Analytical Development and Quality Control
$192K - $235K *
Lead analytical development and quality control for sterile parenteral products, ensuring regulatory compliance and successful product launches. Collaborate cross-functionally to establish strategies...
1 week ago
Senior Accounting Supervisor (PST or MST)
$85K - $90K *
Help us lead a dynamic accounting team, overseeing financial operations and ensuring compliance across multiple projects while driving process improvements and fostering collaboration in a remote envi...
1 week ago
Director, Customer Success Management
$135K - $160K *
Lead the charge in scaling our Customer Success Management team, driving product adoption and retention across diverse customer segments. Collaborate cross-functionally to create impactful processes a...
1 week ago
GIS Software Quality Assurance Engineer
$95K - $120K *
Elevate software quality assurance by testing GIS applications and validating complex datasets. Collaborate with developers and GIS specialists to ensure accuracy and reliability in geospatial data fo...
1 week ago
Expand Sales Manager, North America
$110K - $130K *
Join a team that's driving customer success by leading a North American Account Management group. You'll enhance retention and growth, develop talent, and shape strategies to maximize revenue and cust...
1 week ago
Content Marketing Manager - Industrial B2B
$102K - $184K *
Optimize content strategies that engage industrial audiences, translating complex technical concepts into compelling narratives. Drive measurable outcomes through high-value content creation, collabor...
1 week ago
Product and Regulatory Counsel
$170K - $190K *
Empower innovation at the intersection of technology and law. Guide product, engineering, and compliance teams in navigating regulatory landscapes and mitigating risks related to AI and machine learni...
Reposted 1 week ago
$150K - $180K *
Join a dynamic team where you will enhance patient care and drive community health initiatives. Collaborate with professionals to deliver exceptional dental services while enjoying competitive compens...
1 week ago
Regional Sales Director - Large Enterprise Diversified Industries
$174K - $261K *
Empower enterprise transformation by leading a specialized sales team focused on cloud, data, and AI solutions. Drive strategic partnerships, coach high-performing sellers, and enhance technology stra...
1 week ago
Sr. Marketing Communications Manager
$99K - $166K *
Elevate marketing impact by leading multi-channel campaigns in healthcare. Drive strategic initiatives, ensure brand consistency, and collaborate cross-functionally to maximize engagement and measurab...
1 week ago
Global Strategic Partnership Director
$150K - $180K *
Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...
1 week ago
$200K - $240K *
Empower revenue growth by leading sales strategy and building executive relationships. Drive new business acquisition and expand existing accounts through consultative selling and collaboration with c...
Reposted 1 week ago
$156K - $180K *
Empower clients by owning technical relationships for the Enterprise Suite, guiding them from discovery to implementation. Collaborate with teams to enhance adoption and resolve issues, ensuring seaml...
1 week ago
Director, Utility Field Services
$215K - $235K *
Transform operations at multiple locations by leading field services, ensuring safety, quality, and profitability while driving growth in relay protection and controls. Collaborate with teams to execu...
1 week ago
Data Center Facility Manager, Data Center Engineering Operation
$116K - $173K *
Oversee critical operations within a data center, ensuring high-quality performance and safety. Manage teams of technicians, coordinate with vendors, and lead improvement projects while maintaining op...
Reposted 1 week ago
$110K - $130K *
Drive innovative solutions by leveraging data analytics and strategic counsel to enhance client performance. Collaborate with high-performing teams to deliver tailored insights for transformational ev...
1 week ago
Software Architect (AWS/Azure)
$101K - $135K *
Join a team that's shaping the future of healthcare technology by designing and enhancing our build and delivery infrastructure. Collaborate with architects and developers to implement best practices...
1 week ago
Forward Deployed Engineer - US Remote
$157K - $185K *
Join a team that's building cutting-edge data infrastructure for enterprises. As a Forward Deployed Engineer, you'll create production-quality agents and integrations directly within customer environm...
1 week ago
Wealth and Investment Portfolio Manager III
$95K - $115K *
Champion client success by managing complex investment portfolios, ensuring alignment with corporate objectives, and delivering exceptional service while staying abreast of market trends and strategie...
1 week ago
Wealth and Investment Portfolio Manager III
$95K - $115K *
Unlock potential by managing complex investment portfolios, collaborating with clients to optimize performance, and driving strategic recommendations while staying abreast of market trends and providi...
1 week ago
Wealth and Investment Portfolio Manager III
$95K - $115K *
Transform client portfolios by managing complex investments, ensuring alignment with objectives, and delivering exceptional service while staying updated on market trends and strategies...
1 week ago
Staff Technical Program Manager
$120K - $145K *
Drive execution of complex technical initiatives, translating business vision into actionable programs. Collaborate with cross-functional teams to ensure alignment with company objectives and measurab...
1 week ago
$65K - $128K *
Contribute to exceptional customer experiences by managing vehicle repair processes, educating clients on insurance and repair techniques, and ensuring quality standards are met throughout each repair...
1 week ago
Tax Manager - Private Client Services
$80K - $95K *
Unlock potential by leading a dynamic team in tax management, overseeing client engagements, and ensuring compliance. Foster professional growth while building impactful client relationships and stayi...
1 week ago
Learning /Change Specialist - Live Instruction
$75K - $95K *
Join a team that's dedicated to delivering engaging, role-based training for federal enterprise applications. Collaborate with multidisciplinary partners to enhance user proficiency and ensure measura...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.