Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$231K - $244K *

Lead the charge in shaping proactive legal strategies to navigate evolving regulatory landscapes, ensuring compliance and fostering collaboration across teams, while addressing legislative challenges...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$193K - $244K *

Support business growth by drafting and negotiating partner agreements, providing strategic legal advice, and leading cross-functional projects. Collaborate with internal teams to ensure compliance an...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$192K - $202K *

Lead the technical roadmap and modernize data solutions infrastructure, enhancing off-platform integrations and measurement capabilities while driving AI-first engineering initiatives and cross-team c...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$128K - $135K *

Unlock potential by expanding grassroots engagement across key regions, connecting with shoppers and communities to advocate for app-based workers and food security. Drive digital strategies and build...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$99K - $132K *

Join a team that's shaping the future of technology solutions. Leverage your technical and sales expertise to architect innovative solutions that drive business value for enterprise customers in a dyn...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$111K - $167K *

Engage with clients to identify needs and drive successful adoption of quantum solutions. Collaborate with internal teams to deliver value, provide expert technical support, and foster long-term relat...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$159K - $254K *

Join a dynamic team to design and deliver innovative Android system applications, enhancing device management and user experience. Collaborate across functions to build scalable solutions that empower...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $105K *

Drive the adjudication of complex workers compensation claims, ensuring timely resolutions and client satisfaction. Collaborate with a dynamic team to deliver innovative solutions while leveraging a g...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$151K - $309K *

Innovate AI-driven automations for customer care, enhancing workflows and agent efficiency. Collaborate across teams to transform service operations, leveraging intelligent systems for improved custom...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $110K *

Support client retention by managing small employer group accounts, fostering relationships with clients and carriers, and suggesting new coverage options. Collaborate in a remote environment, leverag...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $160K *

Unlock potential by providing expert legal counsel on commercial agreements while collaborating with cross-functional teams to balance legal risk with business objectives in a dynamic and fast-paced e...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Drive enterprise sales by closing new and existing accounts, leveraging deep product knowledge and customer relationships to exceed revenue targets and deliver innovative solutions in the big data and...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$143K - $179K *

Lead cross-functional initiatives, optimizing governance and operational readiness for programs. Collaborate with stakeholders to enhance portfolio execution, reporting, and PMO capabilities, driving...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K *

Lead the charge in developing innovative full-stack solutions that enhance workflow automation in wealth management. Collaborate with a dynamic team to create impactful features using modern technolog...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Join us to lead generative engine optimization strategies, transforming insights into actionable plans across SEO, content, and digital PR. Collaborate with a dynamic team to enhance client visibility...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $210K *

Join a dynamic team to lead and define technology strategy, ensuring exceptional engineering execution across multidisciplinary teams while delivering high-quality products that align with business go...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$175K - $200K *

Build innovative interfaces that enhance AI development and observability. You'll design and prototype user experiences that empower AI teams to understand and improve their applications through effec...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$165K - $215K *

Engage with innovative AI/ML teams to drive customer success in leveraging AI. You'll cultivate client relationships, manage adoption, and ensure measurable impacts through tailored solutions and stra...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by joining a dynamic Global SRE team focused on enhancing software reliability and observability. Collaborate with teams to implement best practices and innovative solutions, ensuring...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $190K *

Engage in building strategic partnerships that drive revenue growth. Collaborate with global tech partners to ensure effective integration and delivery. Lead initiatives that enhance the operational l...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$180K - $230K *

Lead the charge in financial strategy and operational excellence, overseeing corporate finance, property management accounting, and shared services. Drive profitability and efficiency while ensuring r...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in Epic solutions delivery by providing expert support, managing projects, and mentoring team members. Shape the future of healthcare IT by aligning technical teams with stakeholder ne...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$180K - $190K *

Empower our team to drive innovation by developing crucial AI tools that enhance operational efficiency. Oversee governance, training, and metrics to ensure impactful adoption across departments while...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

$145K - $169K *

Lead strategic franchise operations to drive growth and execution excellence across the Advanced Hydration portfolio, fostering collaboration with bottlers and ensuring alignment with national strateg...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$170K - $184K *

Champion the delivery and strategic growth of government programs, leading cross-functional teams to drive excellence and innovation. Collaborate with stakeholders to enhance service quality and finan...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.