Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Workday Payroll Consulting Manager
$175K - $190K *
Innovate with us as a strategic consultant, guiding ERP and Payroll transformations. Leverage your Workday expertise to shape client strategies, enhance operational readiness, and drive impactful chan...
1 week ago
Digital Demand Generation Manager
$80K - $95K *
Join a dynamic team as you lead digital marketing initiatives, focusing on webinars and paid advertising to drive engagement and generate leads. Collaborate with stakeholders to optimize strategies an...
1 week ago
Channel Development Manager - Ohio Valley
$110K - $130K *
Empower channel growth by managing key partnerships, driving sales acceleration, and collaborating with cross-functional teams to exceed performance goals in the Ohio Valley Region...
1 week ago
Staff Backend Engineer - Infrastructure Access - US
$135K - $160K *
Transform the Teleport Core Product by tackling performance, scalability, and security challenges. Lead a distributed team to design, develop, and implement high-quality solutions while enhancing obse...
1 week ago
Head of Clinical Quality and Regulatory
$208K - $220K *
Drive enterprise leadership in clinical quality and regulatory readiness, ensuring consistent standards and governance across regions. Collaborate with stakeholders to translate quality insights into...
1 week ago
$120K - $145K *
Drive the design and optimization of Oracle CX data architecture, ensuring effective data conversion and integration. Collaborate with cross-functional teams to enhance customer experience through inn...
1 week ago
Oracle ERP Solution Architect - Procurement
$120K - $145K *
Champion innovative Oracle Cloud ERP solutions by leading design and implementation of Procure-to-Pay processes. Collaborate with stakeholders to translate business needs into effective, scalable arch...
1 week ago
Regional Sales Director - Knoxville
$180K - $215K *
Elevate regional sales performance by leading a high-performing team, executing launch strategies, and fostering customer relationships in a dynamic environment. Drive accountability and collaboration...
1 week ago
$138K - $172K *
Empower revenue teams as a Senior Business Systems Analyst, driving efficiency through Salesforce architecture, process design, and actionable data across GTM, Marketing, Sales, and Customer Success o...
Reposted 1 week ago
$76K - $148K *
Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...
Reposted 1 week ago
$80K - $110K *
Lead the charge in transforming K-12 financial solutions by engaging C-level officials. Drive sales cycles, build relationships, and leverage insights to exceed quotas while collaborating with interna...
1 week ago
Discovery Implementation Manager
$80K - $115K *
Shape the future of client onboarding by leading implementation processes, ensuring satisfaction, and driving best practices in a dynamic environment. Collaborate with teams to enhance client experien...
1 week ago
Corporate Brand and Design Lead
$110K - $130K *
Transform your career by leading brand identity and design initiatives, driving AI integration in creative processes, and collaborating across teams to elevate visual storytelling and brand consistenc...
1 week ago
$110K - $130K *
Lead the charge in transforming complex genomic data into compelling narratives that resonate with audiences, driving engagement across diverse channels while collaborating with cross-functional teams...
1 week ago
$120K - $150K *
Empower a cross-functional team by owning the end-to-end design experience for a key product area, enhancing communication for families and educators while mentoring fellow designers and leveraging AI...
1 week ago
Senior Brand Marketing Manager, Social and Community
$112K - $140K *
Join a team that's shaping the voice of a vibrant music community. Drive organic social strategy, engage creators, and manage community programming while leveraging data to enhance our impact and grow...
1 week ago
Associate Director, Clinical Trial Management - Full-Service
$120K - $150K *
Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...
1 week ago
Supplier and Procurement Manager
$110K - $130K *
Drive procurement excellence by managing vendor networks and asset supply chains for remote work solutions. Collaborate across teams to ensure scalable, compliant, and efficient deployment strategies...
1 week ago
$128K - $148K *
Join a dynamic team as you drive utility-scale clean energy projects, managing their lifecycle from strategy to execution. Collaborate with experts to deliver innovative power solutions across key U.S...
1 week ago
$217K - $237K *
Lead the development of innovative utility-scale clean energy projects, driving strategy and execution across diverse markets. Collaborate with experts to tackle complex challenges and deliver high-im...
1 week ago
$80K - $95K *
Discover a dynamic role focused on building relationships with credit unions to drive referrals and revenue. Collaborate with stakeholders, manage partnerships, and execute strategies that enhance AFA...
1 week ago
Medical Review Nurse - Commercial DME Auditor
$80K - $95K *
Transform healthcare auditing by conducting thorough medical claims reviews. Collaborate with a dynamic team to ensure compliance and improve processes while working remotely in a fast-paced environme...
1 week ago
$122K - $176K *
Join a team that's redefining cybersecurity marketing. Leverage your expertise to craft compelling narratives, drive product launches, and influence stakeholders, all while contributing to a rapidly g...
1 week ago
AI Security Sales Executive, Public Sector
$157K - $185K *
Innovate the future of AI Security sales by owning the full sales cycle, targeting enterprise accounts, and collaborating with cross-functional teams to drive growth and shape product offerings in a r...
1 week ago
Manager II, Engineering - Kubernetes Platform
$177K - $364K *
Empower a team of engineers to enhance Kubernetes platform infrastructure, driving reliability, security, and efficiency while collaborating across departments to achieve strategic goals and operation...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.