Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
$80K - $95K *
Manage all facets of a federal travel program, ensuring compliance and efficiency in a high-volume environment. Drive improvements in processes and provide urgent support for travelers, while maintain...
1 week ago
$100K - $120K *
Execute comprehensive program management for a critical Air Force contract, leading a diverse team to ensure compliance, quality, and performance across multiple global operations while maintaining 24...
1 week ago
$80K - $95K *
Lead the charge in program management excellence, ensuring seamless operations and compliance across diverse teams while supporting critical Air Force contract initiatives and rapid-response readiness...
1 week ago
$90K - $110K *
Drive the successful execution of multiple e-discovery projects, collaborating with legal teams and mentoring junior staff. Ensure quality standards, manage budgets, and maintain client relationships...
1 week ago
Lead Consultant, AI & Analytics
$120K - $145K *
Drive the future of AI & Analytics by leading client relationships, providing strategic guidance, and delivering innovative solutions. Leverage your expertise to enhance service delivery and ensure al...
1 week ago
$120K - $150K *
Accelerate progress at the forefront of newborn health by leading strategic initiatives, managing multi-country programs, and driving impactful interventions to reduce neonatal mortality and stillbirt...
1 week ago
$85K - $100K *
Help us optimize Epic applications by leading projects, troubleshooting issues, and ensuring seamless integration. Collaborate with teams to enhance workflows and provide expert support, all while mai...
1 week ago
$230K - $250K *
Take ownership of driving new business by selling enterprise solutions to independent insurance agencies. Utilize your sales expertise to build relationships, engage prospects, and close deals while c...
1 week ago
$110K - $130K *
Lead the charge in building strategic relationships with key travel agencies, optimizing settlement operations, and enhancing distribution technologies to drive efficiency and growth in the travel eco...
1 week ago
$190K - $300K *
Build strategic relationships with scientific leaders to drive innovation in Pulmonary Hypertension. Engage in scientific exchange, support research initiatives, and enhance understanding of therapeut...
Reposted 1 week ago
$67K - $100K *
Drive operational excellence by supporting the development and maintenance of standardized playbooks, SOPs, and workflows. Collaborate with cross-functional teams to ensure clarity and consistency in...
1 week ago
Director - Portfolio Valuation & Decision Analysis
$112K - $236K *
Drive strategic decision-making by evaluating investment alternatives and lifecycle opportunities. Collaborate with cross-functional teams to optimize portfolio value and support program planning thro...
1 week ago
Senior Infrastructure Engineer- Secure Developer Platforms (Azure/VDI)
$125K - $150K *
Lead the charge in building a secure, self-service developer sandbox on Azure, delivering non-persistent desktops and managing the entire stack from landing zone to golden image while ensuring complia...
1 week ago
$100K - $120K *
Empower project success by leading field operations, ensuring safety, quality, and schedule adherence while managing complex construction projects and coordinating with stakeholders for optimal result...
1 week ago
$150K - $180K *
Accelerate your career by leading Army business development, transforming priorities into funded opportunities. Drive strategy from engagement to award, collaborating with key stakeholders to ensure s...
1 week ago
AI Security Sales Executive, Bay Area
$157K - $185K *
Analyze and own AI Security sales in your territory, driving the full sales cycle from prospecting to closing. Collaborate with Account Executives to penetrate enterprise accounts and shape product of...
1 week ago
$183K - $220K *
Lead talent acquisition and relations, managing a team to secure top instructors. Drive strategic partnerships and streamline operations while maintaining high-profile relationships and ensuring succe...
1 week ago
Global Solution Architect - Automation - Remote
$166K - $200K *
Lead impactful solutions as a Global Solution Architect, driving business value through strategic customer engagement and technical expertise. Collaborate with sales teams to architect innovative auto...
1 week ago
$75K - $90K *
Drive innovative advertising strategies by transforming customer insights and performance data into compelling creative content. Collaborate with cross-functional teams to enhance product visibility a...
1 week ago
$125K - $145K *
Drive customer success by optimizing technical adoption of the AIOps platform, ensuring enterprise clients achieve measurable outcomes through strategic partnerships and expert guidance in incident ma...
1 week ago
$126K - $200K *
Lead technical solutions architecture for HPE storage platforms, guiding partners and sales teams in developing resilient infrastructure solutions. Drive engagement, enablement, and strategic initiati...
1 week ago
VP, In Vitro - Scientific Operations
$180K - $220K *
Transform global in vitro scientific operations by leading expansive teams and driving innovation across oncology and immunology studies. Ensure operational excellence, harmonize multi-site workflows...
Reposted 1 week ago
Senior Full Stack Software Engineer (Go, AWS, GCP)
$165K - $260K *
Drive the development of an intelligent content delivery network, optimizing web performance through cutting-edge infrastructure and AI. Collaborate with a lean team to transform complex problems into...
Reposted 1 week ago
$120K - $145K *
Join a team that's pioneering the deployment of scalable AI systems, focusing on building robust APIs, optimizing infrastructure, and ensuring reliable operations in a dynamic environment. Drive innov...
1 week ago
$120K - $150K *
Transform the landscape of programmatic media sales by driving new business with mid-sized agencies. Leverage first-party data solutions to enhance marketing strategies and build lasting relationships...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.