Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Senior Associate, Investments & Fund Partnerships - Third Derivative
$84K - $103K *
Shape the future of startup financing by connecting innovative companies with vital capital solutions. Collaborate with founders and investors to develop tailored fundraising strategies and enhance th...
1 week ago
$160K - $175K *
Shape the strategic vision for data products, leading a high-performing team to drive data-informed decisions and enhance product strategy. Collaborate cross-functionally to establish data governance...
1 week ago
Enterprise Sales Account Executive
$110K - $130K *
Unlock potential by leading strategic account management initiatives, driving customer satisfaction and revenue growth through effective relationship building and expansion strategies in a dynamic ent...
1 week ago
$80K - $95K *
Transform airport advertising environments by conducting site visits, developing signage concepts, and collaborating with design teams. This role combines hands-on fieldwork with creative design to en...
1 week ago
Customer Success Manager, Enterprise - Central
$125K *
Transform customer experiences as a key advocate and technical partner, driving onboarding, adoption, and success for Enterprise clients while collaborating across teams to ensure optimal outcomes and...
1 week ago
Senior Corporate Counsel - Legal Transactions
$119K - $221K *
Support dynamic legal processes in tech sales by negotiating complex agreements. Collaborate with cross-functional teams, manage high volumes of transactions, and drive legal department initiatives wh...
Reposted 1 week ago
Senior Manager, Brand & Specialty Rx Contracts
$119K - $186K *
Lead the negotiation and administration of Branded & Specialty Rx contracts, ensuring alignment with business strategies and stakeholder interests. Collaborate with internal teams to optimize processe...
1 week ago
Oracle MFCS/Retail Merchandising lead
$120K - $145K *
Unlock potential by leading the Oracle MFCS merchandising workstream, driving design and delivery for a seamless omnichannel experience. Collaborate with teams to optimize processes and ensure success...
1 week ago
$162K - $243K *
Join a team that's dedicated to advancing clinical trials through strategic oversight and collaboration. Lead project management efforts globally, ensuring quality, cost, and timeline objectives are m...
1 week ago
Associate Director, Client Media Solutions
$95K - $120K *
Accelerate progress at the intersection of media and healthcare by leading integrated planning and strategy for pharmaceutical clients. Drive impactful engagement initiatives while mentoring a talente...
1 week ago
$70K - $95K *
Join a team that's driving business success by building relationships and selling comprehensive HR solutions to small and midsize companies. You'll manage your own pipeline, engage with decision-maker...
1 week ago
Sr. Litigation Specialist (Remote)
$89K - $119K *
Join the charge in managing complex litigated claims, guiding strategy, and negotiating settlements. Leverage your expertise to achieve timely resolutions while balancing costs and exposure in a dynam...
1 week ago
$100K - $120K *
Transform your career by driving new business growth and client success in a dynamic remote environment. Leverage your sales expertise to build strategic partnerships and exceed revenue targets while...
1 week ago
$125K - $150K *
Lead the charge in transforming innovative ideas into impactful AI-driven solutions for public health and medical research. Collaborate with diverse teams to develop MVPs that enhance scientific disco...
1 week ago
$200K - $220K *
Unlock potential by driving partner engagement and growth through strategic channel management. Lead initiatives to onboard and enable partners, ensuring alignment with business objectives while foste...
1 week ago
Assistant General Counsel - Corporate, Commercial & Structured Finance
$245K - $310K *
Champion innovative financing solutions as a strategic legal leader, overseeing structured finance, capital markets, and corporate law. Drive legal execution and team growth while ensuring compliance...
1 week ago
$155K - $165K *
Develop a cutting-edge data ecosystem as a Senior Data Engineer, enhancing analytics, reporting, and machine learning. Collaborate with cross-functional teams to create efficient pipelines and accessi...
Reposted 1 week ago
Product Manager, New Content Initiatives and Analysis
$140K - $175K *
Transform investment research by evaluating and integrating diverse datasets, enhancing AI-driven workflows, and driving strategic content initiatives to elevate platform value and user experience...
1 week ago
$95K - $110K *
Transform creative visions into reality by leading design projects, mentoring teams, and collaborating with clients. Drive strategic branding initiatives while ensuring high-quality deliverables in a...
1 week ago
$105K - $115K *
Innovate the future of Revenue Operations by enhancing systems and processes. Collaborate across teams to solve complex problems, build automation, and drive data insights while providing exceptional...
1 week ago
$180K - $220K *
Engage with cross-functional leaders to elevate product strategy and execution. Drive innovation in product development, leveraging AI to enhance customer value and business performance across a diver...
1 week ago
Chief Information Security Officer (CISO)
$216K - $325K *
Pioneer enterprise security initiatives, ensuring robust cybersecurity and compliance while enabling growth and innovation. Collaborate with cross-functional teams to protect information assets and dr...
1 week ago
Security Engineer, Infrastructure Security
$120K - $145K *
Join us to enhance the security posture of our production platform. As an Infrastructure Security Engineer, you'll drive remediation efforts, build security frameworks, and collaborate with teams to p...
1 week ago
$64K - $134K *
Drive success by managing key accounts, ensuring revenue growth through strategic upselling and relationship building. Collaborate with clients and internal teams to deliver exceptional service and ac...
1 week ago
Principal RAS Partner & Educator
$98K - $132K *
Transform healthcare by leading Risk Adjustment strategies and educational initiatives. Collaborate with teams to enhance coding accuracy and documentation, ensuring compliance and delivering impactfu...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.