Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Director of Business Development - Army/Air Defense
$350K - $380K *
Lead the charge in driving growth within the U.S. Army by developing strategic relationships and capturing opportunities in Air Defense and Counter-UAS programs, ensuring alignment with mission needs...
1 week ago
Regional Sales Director- Southeastern US Region
$120K - $160K *
Transform regional sales dynamics by leading an energetic team in the Southeast US, focusing on driving sales initiatives, coaching representatives, and enhancing brand visibility across various HVAC...
Reposted 1 week ago
Vice President Technology / Entertainment (remote)
$210K - $250K *
Drive innovation in hospitality technology by leading AI-native solutions across hotels, casinos, and restaurants. Build strong client relationships and mentor a high-performing team to enhance guest...
1 week ago
$95K - $120K *
Lead the charge in tax compliance management, overseeing multi-state filings, audits, and team mentorship. Drive process improvements and ensure regulatory adherence across diverse jurisdictions while...
Reposted 1 week ago
$90K - $108K *
Analyze and optimize enterprise data workflows, ensuring stakeholders access accurate data. Collaborate on analytics development, support data transformation in Microsoft Fabric, and enhance reporting...
1 week ago
Senior Product Marketing Manager, Corporate Internal Audit
$125K - $150K *
Champion product positioning and go-to-market strategies, ensuring alignment between product and sales teams. Drive messaging and enablement for corporate internal audit solutions in a fast-paced envi...
1 week ago
Quality Operations Manager (Contract)
$100K - $120K *
Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...
1 week ago
Mississippi Licensed Attorney- (Remote in MS)
$75K - $90K *
Execute high-volume case management for clients with security interests in assets. Utilize strong negotiation and litigation skills to resolve disputes efficiently while maintaining meticulous documen...
1 week ago
Mid-Level MuleSoft Integration Developer (Remote)
$110K - $145K *
Transform the future of digital services by developing and integrating MuleSoft capabilities. Collaborate with diverse teams to deliver secure, reliable, and maintainable solutions that meet mission-a...
1 week ago
$112K - $126K *
Elevate AI capabilities by building and maintaining governed solutions. Collaborate cross-functionally to translate business needs into technical designs, ensuring ethical AI use and robust integratio...
1 week ago
ERS Electrical Commissioning Engineer - Remote
$95K - $115K *
Empower project success by leading electrical commissioning for critical systems. Oversee planning, execution, and testing to ensure compliance and performance across diverse infrastructure projects...
Reposted 1 week ago
RN Nurse Clinical Documentation Improvement Specialist
$114K *
Advance clinical documentation quality by conducting thorough reviews and facilitating physician interactions to enhance accuracy and compliance in medical records, ensuring optimal patient care and r...
1 week ago
Director, North American B2B Secular Shift – B2C Retail & Restaurants
$158K - $304K *
Lead and shape the B2C Retail & Restaurants growth strategy, driving innovative payment solutions and fostering key partnerships to expand market presence and elevate customer engagement in North Amer...
Reposted 1 week ago
Director, North American B2B Secular Shift – Construction & Trades
$158K - $304K *
Lead the charge in transforming the Construction & Trades segment by driving market strategies, building dynamic partnerships, and executing growth initiatives to elevate payment solutions and moderni...
Reposted 1 week ago
Senior Principal AI Engineer- AI Center of Excellence
$212K - $339K *
Shape the future of AI infrastructure by architecting secure, scalable platforms for LLM training and production. Collaborate with cross-functional teams to solve complex challenges and drive innovati...
Reposted 1 week ago
Advisor, Competitive Intelligence – Inside-the-Data-Center Technologies
$114K - $182K *
Analyze competitive landscapes in ITDC technologies, providing strategic insights and support across functions to enhance market positioning and respond to emerging threats effectively...
1 week ago
$150K - $180K *
Champion new business development by identifying and converting revenue opportunities across enterprise customers and technology partners, driving growth and establishing long-term relationships in a...
Reposted 1 week ago
Dataverse / Data Science Lead (CBP)
$111K - $180K *
Unlock your potential as a Data Science Lead, driving analytical strategies and enhancing mission-critical capabilities for national security. Collaborate with a multidisciplinary team to tackle compl...
1 week ago
Organizational Change Management (OCM) Senior Consultant
$115K - $135K *
Join a team that's transforming Medicaid agencies through expert OCM strategies. Leverage your project management and change management skills to enhance health outcomes and build stronger communities...
1 week ago
Technical Product Manager - Search and Discovery
$116K - $146K *
Develop customer-centric digital product strategies and deliver innovative solutions by collaborating with cross-functional teams, ensuring quality and efficiency in the plumbing and HVAC supply chain...
Reposted 1 week ago
$90K - $110K *
Join a team that's dedicated to enhancing software quality through innovative test automation. Collaborate with cross-functional teams to design, develop, and execute automated testing solutions that...
1 week ago
Vice President, Global Direct Sales
$210K - $250K *
Lead the charge in expanding a global direct-sales organization by developing and executing strategies that drive customer acquisition, retention, and measurable performance aligned with commercial ob...
Reposted 1 week ago
Chief Compliance Officer (CCO) - US
$200K - $280K *
Help us architect a robust regulatory framework that empowers GPs to thrive in complex financial markets. You will lead compliance initiatives, ensuring operational integrity and strategic alignment w...
1 week ago
$190K - $237K *
Unlock the potential of global communications by leading strategic initiatives that enhance brand visibility, media engagement, and corporate storytelling. Drive impactful narratives that position the...
1 week ago
Team8 Stealth Cyber Startup- Account Executive
$145K - $165K *
Empower enterprise sales by driving new-logo deals from initial contact to close. Collaborate with Solution Engineers and founders to shape strategies, build pipelines, and expand relationships in the...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.