Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,580

Sort By: Relevance

$95K - $115K *

Champion project delivery by overseeing HV cable testing projects across North America. Ensure alignment with client expectations while managing resources, schedules, and budgets for successful comple...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$220K - $250K *

Lead the charge in expanding oncology product reach by developing strategic territory plans, nurturing key relationships, and delivering impactful scientific presentations to healthcare professionals...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$157K - $224K *

Champion the evolution of developer tooling and CI/CD pipelines, leading a global team to enhance operational efficiency and drive platform modernization for a multi-tenant SaaS environment, ensuring...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $140K *

Shape the future of industrial water solutions by driving sales growth, managing key accounts, and fostering enduring partnerships with customers and teams to enhance sustainable business outcomes and...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$115K - $160K *

Join a team that's dedicated to enhancing global security through advanced incident response and forensic analysis. Collaborate with top professionals to protect organizations from sophisticated threa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive operational excellence as a Continuous Improvement Engineer, collaborating with teams to optimize processes and implement sustainable solutions that enhance safety, quality, and efficiency in ma...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$75K - $90K *

Transform financial insights into strategic initiatives, supporting planning and analysis as the organization scales. Collaborate across teams to enhance budget management, reporting, and performance...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $102K *

Elevate your career by reviewing and editing environmental and property assessments. Collaborate with field staff to ensure report accuracy and quality, while providing technical guidance and maintain...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $120K *

Take ownership of electrical project coordination on utility-scale solar sites. Ensure high-quality installations, manage contractor relationships, and maintain safety and efficiency standards while t...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$140K - $200K *

Optimize project outcomes by leading comprehensive electrical design reviews in renewable energy sectors. Ensure compliance with industry standards while effectively managing timelines and costs for d...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $140K *

Advance your career by driving full-cycle recruitment for diverse Sales and Go-To-Market roles. Collaborate with leadership to attract top talent, enhance candidate experience, and optimize hiring pro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $190K *

Lead and innovate within UJET's Core Infrastructure team, focusing on cloud-native services. Shape strategies for scalable solutions that empower engineers and optimize the infrastructure for thousand...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Transform regional performance by leading a high-performing sales team, driving market adoption, and executing strategic initiatives in the ophthalmic surgical industry to achieve commercial success a...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Lead the national growth strategy in the Government & Military sectors, leveraging $2 trillion in annual spending. This pivotal role will establish Sonepar as the preferred partner in electrical distr...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $270K *

Elevate your career by leading global executive recruiting efforts, shaping talent strategies, and building high-performing teams. Drive impactful searches and foster relationships with senior leaders...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$72K - $97K *

Empower individuals by coordinating personalized care plans for seniors and members with disabilities. Collaborate with healthcare providers and manage caseloads while enjoying a flexible, remote work...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Champion nuclear operations training by developing and implementing programs for licensed and non-licensed personnel, ensuring compliance with NRC and INPO standards while enhancing operational profic...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $115K *

Lead the charge in developing and executing long-range outage plans and budgets, managing capital projects, and ensuring safety and efficiency in power plant operations while collaborating with manage...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $115K *

Shape the future of power plant operations by developing long-range outage plans, managing capital projects, and ensuring safety and efficiency in execution. Collaborate with teams to drive project su...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Shape the future of engineering by overseeing high-quality capital modifications, managing team performance, and ensuring compliance with regulatory standards while driving efficiency and productivity...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$184K - $403K *

Lead the charge in shaping enterprise financial planning, guiding strategic decisions through insightful analyses and robust forecasting. Manage a high-performing team while driving accountability and...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$115K - $120K *

Help us provide impactful virtual counseling to adults and adolescents, addressing emotional and behavioral concerns. You'll manage client sessions, clinical decisions, and documentation while adherin...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $217K *

Join a dynamic team to negotiate and close high-profile commercial agreements, supporting various business units while driving growth in a leading SaaS company. Collaborate closely with sales and prod...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Manage project lifecycles from order to delivery, ensuring quality, budget, and customer satisfaction. Collaborate across teams to drive communication and resolve escalations while championing continu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $160K *

Develop and execute strategies for deployment options across cloud and self-hosted setups, ensuring compliance and security. Collaborate with cross-functional teams to enhance product offerings and dr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.