Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,580

Sort By: Relevance

$100K - $110K *

Empower corporate veterinary groups by driving software adoption and growth. Collaborate with cross-functional teams to develop strategic partnerships, influence decisions, and enhance customer satisf...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to fostering strategic relationships with enterprise customers, ensuring successful adoption and optimization of technology solutions in the financial services sector whil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $150K *

Join a team that's transforming construction project management through technology. Leverage your industry expertise to guide customers in adopting Autodesk solutions, enhancing workflows, and driving...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Join a dynamic team to architect and implement cutting-edge MLOps strategies, leveraging Google Cloud's AI/ML stack. Drive innovation in model lifecycle management and collaborate with cross-functiona...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $115K *

Lead the charge in enhancing customer support by guiding a skilled team of Support Engineers. Balance hands-on technical assistance with operational oversight to ensure a world-class experience for cl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $170K *

Lead the charge in modernizing enterprise security by investigating and mitigating critical vulnerabilities. Collaborate across teams to drive risk reduction and enhance operational effectiveness in a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $150K *

Take ownership of commercial sales in your territory, managing B2B accounts and driving growth. Collaborate with clients and service teams to deliver tailored pest management solutions while utilizing...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$120K *

Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Drive regional sales growth by developing strategies, managing key accounts, and expanding market presence. Engage with K-12 leaders to enhance customer relationships and achieve sales targets while m...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$83K - $138K *

Lead the strategy and performance management for our mobile app and loyalty experience, driving athlete engagement and revenue growth through cross-functional collaboration and data-driven insights. O...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$112K - $132K *

Join a team that's shaping the future of autism care by building robust statistical methodologies. You'll analyze real-world clinical data, ensuring rigorous evaluation of outcomes and social validity...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Champion the growth of strategic travel partnerships by leading enterprise sales efforts, securing high-value accounts, and leveraging modern sales frameworks to drive commercial success in a fast-pac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $110K *

Unlock potential by leading end-to-end payroll processing across multiple US entities, ensuring compliance and accuracy while contributing to the evolution of a global payroll model within a dynamic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Drive high-value sales and elevate team performance by mentoring Account Executives. Leverage your expertise in complex negotiations while managing a strategic pipeline to achieve personal and team su...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$175K - $210K *

Transform business growth by leading strategic sales initiatives, enhancing market presence, and developing tailored solutions for corporate clients. Collaborate with cross-functional teams to drive r...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Drive product excellence by managing testing, documentation, and collaboration across teams. Engage with stakeholders to enhance solutions and ensure quality assurance for optimal deployment and suppo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $85K *

Pioneer in claims management by analyzing complex auto bodily injury claims, ensuring timely resolutions while adhering to industry standards and client expectations. Collaborate with vendors and stak...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Develop and execute innovative strategies for employment law cases. Handle litigation tasks, mentor junior staff, and collaborate with a talented team to deliver exceptional legal services in a flexib...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$150K - $180K *

Join a team that's redefining product marketing in cybersecurity. Lead a small team to craft compelling narratives, drive go-to-market strategies, and collaborate across functions to ensure product su...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Champion growth by driving enterprise sales in cybersecurity. Collaborate with cross-functional teams to build strategies, manage complex sales cycles, and establish long-term partnerships with key st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$118K - $180K *

Grow your career with a dynamic team focused on designing innovative HVAC systems. Engage in challenging projects, collaborate with experts, and contribute to the development of cutting-edge solutions...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$152K - $253K *

Drive impactful health informatics initiatives across multiple states, enhancing care delivery through strategic partnerships and technology alignment. Collaborate with health systems to optimize work...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in managing complex clinical trials, ensuring timely delivery, budget adherence, and high-quality outcomes while collaborating with multidisciplinary teams and stakeholders to enhance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $125K *

The Senior Consultant - Workday Benefits at Makse Group is responsible for delivering high-quality implementations and support for Workday Benefits solutions. This role requires strong functional know...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive compliance and contract administration for federal government contracts. Collaborate with cross-functional teams to ensure adherence to regulations, manage audits, and maintain records. Shape pr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.