Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
Senior Sales Analytics Manager
$115K - $135K *
Drive impactful sales analytics by developing methodologies that enhance performance insights, forecasting, and strategic planning. Collaborate with stakeholders to translate complex data into actiona...
5 days ago
$115K - $175K *
Advance market share by driving strategic growth initiatives within the US Mid-Market and Enterprise carrier segments. Lead a high-performing team to execute regional plans, leveraging deep telecom ex...
5 days ago
$150K - $250K *
Lead the charge in driving sales and building relationships within the roofing industry. As a key liaison, you'll connect with contractors and clients to promote GAF's residential products, ensuring s...
5 days ago
Director, Patient Centred Outcomes
$212K - $318K *
Shape the future of patient-centered outcomes in oncology by leading global strategies for clinical assessments and patient experience data, ensuring impactful evidence generation and regulatory succe...
5 days ago
Lead Clinical Research Associate
$121K - $182K *
Manage clinical monitoring activities for multiple trials, providing mentorship and oversight to CRAs. Collaborate with teams to ensure compliance and quality, while addressing site-level issues and e...
5 days ago
Business Development Engineer (BDE), US Air Force
$100K - $140K *
Unlock potential by bridging technical radio frequency capabilities with US Air Force needs. Collaborate with engineering and business teams to demonstrate and support advanced communication solutions...
5 days ago
Business Development Engineer (BDE), US Marine Corps
$100K - $140K *
Support the U.S. Marine Corps by bridging technical radio capabilities with defense needs. Collaborate with engineering teams to demonstrate and evaluate advanced communication systems in diverse oper...
5 days ago
Business Development Engineer (BDE), USSOCOM
$100K - $140K *
Join a team that's redefining tactical communications for defense applications. Leverage your engineering expertise to bridge technical capabilities with USSOCOM requirements, supporting innovative so...
5 days ago
IT Clinical Informaticist - Dental Support
$71K - $99K *
Join a team that's dedicated to enhancing clinical practices through effective IT solutions. This role involves training, system maintenance, and collaboration with healthcare professionals to optimiz...
5 days ago
$119K - $149K *
Innovate with us to shape the future of mobile experiences. As a Senior Mobile Engineer, you'll drive the development of high-quality iOS applications, collaborating across teams to ensure performance...
5 days ago
OFAS Accounting Services Manager
$90K - $110K *
Champion client engagement delivery by leading teams, managing workflows, and ensuring financial performance. Collaborate with senior leaders to enhance client relationships and drive practice growth...
5 days ago
Warehouse Lead Industrial Engineer - Ryder Last Mile (remote)
$105K - $125K *
Champion continuous improvement initiatives to enhance operations through data analytics and engineering methodologies. Drive performance in safety, quality, and cost, while managing impactful project...
Reposted 5 days ago
$90K - $100K *
Join a team that's redefining telecommunications by providing expert Tier 3 and 4 support, engineering, and deployment for cutting-edge voice solutions. Collaborate with peers and mentor junior member...
5 days ago
Lead Customer Insights & Data Analyst
$115K - $125K *
Lead transformative customer insights initiatives, integrating complex data to enhance marketing strategies. Shape data processes and develop analytical solutions to empower decision-making and drive...
Reposted 5 days ago
Clinical Account Executive Hereditary Cancer - PNW
$105K - $130K *
Unlock potential by driving sales growth in a defined territory through strategic relationship management and promotion of genetic diagnostic testing services to healthcare professionals and instituti...
5 days ago
Director, Third-Party Risk Management
$125K - $150K *
Join a team that's enhancing third-party risk management by leading strategic oversight, driving program improvements, and collaborating with stakeholders to ensure compliance and effective risk mitig...
5 days ago
$98K - $127K *
Partner with us to enhance organizational effectiveness by guiding staff engagement, career development, and strategic decision-making. Collaborate across teams to foster a culture of growth and suppo...
5 days ago
$130K - $140K *
Drive complex initiatives in life insurance and annuities, leveraging deep expertise to manage projects across teams and vendors. Ensure alignment with client goals while implementing AI-driven soluti...
5 days ago
$95K - $115K *
Drive cybersecurity excellence by supporting the Tactical Assault Kit's security efforts. Collaborate with teams to integrate security best practices, enhance compliance, and tackle real-world securit...
5 days ago
$112K - $179K *
Unlock innovative cloud solutions by designing and governing enterprise architectures on AWS and Azure. Collaborate with cross-functional teams to ensure compliance, optimize performance, and lead clo...
5 days ago
$104K - $166K *
Lead and execute comprehensive penetration testing assessments to identify and remediate security vulnerabilities across applications, networks, and cloud environments, while providing technical guida...
5 days ago
Senior File Transfer Administrator
$104K - $166K *
Transform enterprise file transfer operations by leveraging your expertise in IBM Sterling and Unix/Linux systems. Drive efficiency and security in a critical financial services environment while coll...
5 days ago
$104K - $166K *
Lead strategic sourcing and procurement for Defense and Health sectors, managing a team to drive supplier value, cost savings, and compliance while supporting growth and operational excellence across...
5 days ago
Cloud Computing, Senior Advisor
$112K - $179K *
Optimize cloud infrastructure and CI/CD processes as a Cloud DevOps Engineer. Collaborate with Agile teams to enhance security, automate deployments, and ensure mission-critical support while leveragi...
5 days ago
Sr. Staff Attorney (Regulatory)
$142K - $177K *
Lead legal initiatives by drafting documents, managing records, and providing counsel. Collaborate with executives to shape organizational direction while ensuring compliance and supporting continuous...
5 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.