Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
$161K - $190K *
Join us to define and evolve the architecture of a cutting-edge digital platform, guiding engineering decisions and establishing shared services for scalable, secure, and reliable solutions that empow...
4 days ago
Medical Education Content Manager
$85K - $115K *
Elevate healthcare education by developing evidence-based content for clinicians. Collaborate with experts to create innovative learning materials that address practice gaps and enhance professional s...
4 days ago
$135K - $160K *
Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...
4 days ago
Senior Director, Head of Research & Early Development
$228K - $342K *
Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...
4 days ago
$95K - $115K *
Join a team dedicated to driving financial excellence in manufacturing. Oversee accounting, provide insights, and ensure compliance as the financial partner for plant operations, fostering a culture o...
Reposted 4 days ago
$100K - $110K *
Advance your career by conducting vital physical security evaluations across multiple data centers. Collaborate with teams to enhance security measures and protect critical infrastructure while engagi...
4 days ago
$95K - $115K *
Join a team that's redefining product marketing by driving impactful go-to-market strategies, enabling sales teams, and translating complex product features into clear customer value across diverse ma...
4 days ago
Enterprise Account Executive - Financial Services
$240K - $330K *
Join a team that’s pioneering growth in revenue intelligence by driving new business opportunities in financial services and healthcare. Leverage your extensive sales expertise to build relationships...
Reposted 4 days ago
$85K - $90K *
Elevate culinary standards by managing kitchen operations in a dynamic healthcare setting, leading a dedicated team to deliver high-quality, nutritious meals while ensuring compliance with safety regu...
Reposted 4 days ago
$172K - $216K *
Help us drive growth in the utilities sector by leading a high-performing sales team. You'll shape strategies, build relationships, and coach sellers to excel in complex, multi-year deals, ensuring al...
4 days ago
Key Account Leader, Corrections
$120K - $180K *
Unlock potential by leading full-cycle sales in the corrections sector, driving innovative drone solutions. Collaborate with diverse teams to build trust and pipeline, while navigating complex agency...
4 days ago
$150K - $180K *
Champion innovative design solutions as a Principal Product Designer, leading UX strategy and AI experiences for a complex platform. Drive workflow transformation and mentor talent while shaping the f...
4 days ago
$110K - $130K *
Unlock potential by driving pipeline visibility and forecasting accuracy. Collaborate with Sales, Marketing, and Finance to enhance workflows and insights, ensuring clean data and effective GTM strate...
Reposted 4 days ago
Senior Manager - Dazodalibep HCP Launch Marketing
$149K - $202K *
Transform the HCP launch landscape by leading innovative marketing initiatives for a groundbreaking treatment in Sjögren's disease. Collaborate cross-functionally to engage healthcare professionals an...
4 days ago
$110K - $130K *
Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...
4 days ago
Pre-Sales Solutions Engineer, HCM
$95K - $125K *
Join a team that's transforming HR and payroll solutions by engaging clients, conducting tailored demos, and bridging business needs with technical expertise to enhance workforce management and compli...
4 days ago
Account Executive, NAS Product Specialist
$124K - $198K *
Transform your career by owning and accelerating Unstructured data protection sales. Leverage your technical expertise to drive growth, engage stakeholders, and win competitive deals in a dynamic, quo...
4 days ago
Clinical Specialist, Philadelphia
$80K - $95K *
Empower clinical excellence by delivering expert technical support for neurovascular products. Collaborate with healthcare professionals to enhance patient care, drive product adoption, and ensure suc...
4 days ago
General Manager, Healthcare Practices
$275K - $325K *
Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...
4 days ago
$80K - $90K *
Elevate your career by building and maintaining a network of specialist consultants and physicians. Drive business growth and enhance clinical trial delivery through strong relationships and strategic...
4 days ago
Senior Account Executive - Sports Vertical
$130K - $150K *
Unlock potential by driving new business growth in the sports industry, leveraging your extensive network and sales expertise to close strategic deals and innovate through AI solutions for sports orga...
4 days ago
$69K - $101K *
Manage supplier relationships and procurement processes to ensure seamless production. Collaborate with cross-functional teams to track costs, monitor delivery performance, and resolve material shorta...
4 days ago
Business Development Manager- WA/OR
$95K - $115K *
Accelerate progress at the forefront of commercial fleet sales by driving new customer acquisition and expanding market share through strategic relationship building and consultative selling in a dyna...
4 days ago
Manager, Infrastructure Governance
$125K - $178K *
Accelerate progress at the forefront of cloud security governance, leading a dynamic team to enhance compliance, drive automation, and ensure robust risk management across multi-cloud environments...
4 days ago
Self-Managed Business Development Manager- East Region
$100K - $120K *
Champion growth by driving new customer acquisition and fleet sales within your territory. Leverage consultative selling and relationship-building to secure small to medium-sized business clients, enh...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.