Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$121K - $262K *

Transform credit risk management by leading the Continuous Review program, ensuring compliance and effectiveness across portfolios. Collaborate with executives and teams to identify risks, enhance pro...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Finance & Insurance

$96K - $207K *

Optimize cash management solutions by leveraging expertise in technology and client processes. Collaborate with teams to design and implement strategies that enhance operational efficiency and drive r...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$54K - $111K *

Drive compliance and client satisfaction by managing SBA loan pipelines, ensuring regulatory adherence, and collaborating with stakeholders to facilitate smooth closing processes and documentation man...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$121K - $262K *

Drive strategic partnerships and advisory services for business transitions, enhancing client relationships and achieving financial goals through effective collaboration and risk management in wealth...

United StatesRemote

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  •   8 - 10 years exp.  •   Finance & Insurance

$71K - $145K *

Partner with us to design and implement enterprise-level production solutions, leveraging .NET technologies in a collaborative environment. Enhance customer experiences by delivering high-quality cash...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$54K - $111K *

Champion client success by managing relationships, driving product adoption, and ensuring operational excellence. Leverage your expertise to enhance client engagement, resolve issues, and identify gro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $160K *

Transform the planning landscape by leading integrated sales and operations processes. Drive cross-functional collaboration, develop robust planning models, and ensure alignment on business objectives...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$140K - $390K *

Unlock potential by leading the Real World Commercial Analytics team, driving insights for pharma clients. Collaborate with stakeholders to enhance decision-making and accelerate product launches in a...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$58K - $146K *

Elevate regulatory consulting efforts by supporting strategic engagements across pharmaceuticals and medical devices. Collaborate with experts to navigate complex challenges, develop evidence strategi...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $180K *

Champion innovative vaccine research by leading virology and immunology programs. Utilize your expertise to develop assays, analyze data, and mentor teams, driving impactful solutions for public healt...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$168K - $199K *

Shape the future of clinical development by driving scientific strategy and oversight in Hematology programs. Collaborate cross-functionally to ensure compliance, quality, and patient safety in clinic...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$188K - $222K *

Empower clinical innovation by leading the development of hematology programs, ensuring scientific integrity and compliance while collaborating with cross-functional teams to drive successful clinical...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$229K - $262K *

Transform data into actionable insights by leading innovative engineering solutions. Collaborate with cross-functional teams to design and implement scalable data pipelines, ensuring robust performanc...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$229K - $262K *

Drive transformative data initiatives by leading a team of engineers and analysts to design, develop, and implement innovative data solutions that enhance operational efficiency and scalability across...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$209K - $239K *

Drive major technical transformations by leading cross-functional programs that align technology with business goals, ensuring a scalable and efficient delivery of innovative platforms and products fo...

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Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$165K *

Oversee the full sales cycle for enterprise SaaS solutions in regulated industries. Drive strategic engagements with C-level executives, navigate complex buying centers, and build compelling business...

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Today

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Take ownership of developing sales talent and elevating clinical skills across teams. Build trust with healthcare professionals while delivering impactful training and mentoring for both new and exper...

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Reposted today

  •   5 - 7 years exp.  •   Healthcare

$105K - $231K *

Join a team that's dedicated to optimizing Oracle databases for mission-critical medical readiness systems. Collaborate with diverse stakeholders to ensure security, performance, and reliability in a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$90K - $189K *

Lead the charge in coaching agile teams within a scaled framework, ensuring effective planning, execution, and continuous improvement in a collaborative environment while fostering strong stakeholder...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Transform agile teams by coaching and facilitating effective Scrum practices, ensuring successful delivery of solutions in a scaled agile environment while fostering strong stakeholder relationships a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$68K - $143K *

Support audit and compliance efforts for DoD financial systems, ensuring adherence to GAGAS and federal standards. Collaborate with stakeholders to enhance internal controls and audit readiness, drivi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform inpatient coding operations by leading a dedicated team to ensure accurate coding, compliance, and timely billing. Collaborate with clinical and administrative staff to enhance financial per...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$159K - $305K *

Provide vision and expert guidance in managing complex commercial banking portfolios, focusing on clients with revenues of $100MM to $2B. Collaborate with leadership to develop innovative solutions th...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Drive your career with a pivotal role in fostering client relationships and delivering technical solutions in the pharmaceutical sector, ensuring growth and alignment with strategic objectives through...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $108K *

Unlock growth by developing product strategies that enhance customer value and drive sales. Collaborate with cross-functional teams to manage product launches, marketing support, and training, ensurin...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.