Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$210K *

Join a team that's redefining healthcare delivery through telemedicine. This role offers board-certified OB/GYN physicians the chance to provide compassionate, patient-centered care across Massachuset...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$66K - $145K *

Innovate solutions for medication adherence in healthcare. Lead cross-functional initiatives, analyze data, and develop business cases to enhance pharmacy strategies and drive revenue growth. Own proj...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K *

Join a dynamic telemedicine team as a board-certified OB/GYN physician, delivering high-quality virtual care across Massachusetts. Enjoy flexible scheduling while managing diverse clinical cases in a...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$113K - $188K *

Engage in data-driven decision-making by designing and maintaining analytical datasets, optimizing SQL queries, and developing insightful dashboards. Collaborate with cross-functional teams to deliver...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$185K - $344K *

Join a dynamic team driving strategic planning and performance management across analytics capabilities. Lead portfolio governance and execution initiatives to align resources and priorities, ensuring...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$267K - $445K *

Champion AI-driven innovation by leading a high-performing team to develop platforms and capabilities that enhance engineering and scientific collaboration, driving impactful solutions across R&D and...

United StatesRemote

Yesterday

  •   15+ years exp.  •   Healthcare

$100K - $110K *

Transform project execution by leading diverse teams to ensure timely, budget-friendly delivery of high-quality construction projects while fostering strong client relationships and driving business g...

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $113K *

Lead strategic initiatives to enhance advocacy for California's children and youth. Collaborate with stakeholders, manage programs, and drive fundraising efforts to ensure impactful policy changes and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$140K - $180K *

Oversee strategic publisher partnerships across North America, driving revenue growth through innovative advertising solutions. Lead the full sales cycle, develop executive relationships, and collabor...

Reposted yesterday

  •   5 - 7 years exp.  •   Staffing

$145K - $175K *

Lead the charge in building robust MLOps infrastructure to support scalable AI solutions, bridging software engineering and machine learning for reliable production deployments across enterprise envir...

Cambridge, MARemote

Reposted yesterday

  •   8 - 10 years exp.  •   Staffing

$135K - $160K *

Lead innovative sales strategies to drive new business in healthcare technology, focusing on clinical data exchange and interoperability. Engage with C-suite executives to close complex deals and enha...

Reposted yesterday

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Contribute to the development of innovative digital health solutions by owning features from concept to deployment, collaborating with cross-functional teams to enhance patient care through reliable a...

Reposted yesterday

  •   Less than 5 years exp.  •   Staffing

$120K - $145K *

Elevate your career by leading the development of advanced power electronics and embedded control systems. Play a key role in driving innovative solutions from architecture to production, while mentor...

Reposted yesterday

  •   5 - 7 years exp.  •   Staffing

$110K - $188K *

Transform complex initiatives into actionable plans by leading cross-functional teams. Drive strategic program management and business analysis to ensure successful execution and delivery of key proje...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$210K - $303K *

Lead the charge in transforming customer engagement through an AI-native platform, ensuring seamless integration and deployment across global teams while driving compliance, data integrity, and user e...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Drive end-to-end payroll processes across multiple entities, ensuring accuracy and compliance. Manage domestic and international payroll, tax setups, and employee inquiries while building scalable sys...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $207K *

Drive the vision and strategy for innovative Enterprise Data Management services, leading cross-functional teams to deliver scalable, cloud-native solutions that empower investment firms to manage and...

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $180K *

Join us in enhancing the digital servicing experience by collaborating across teams to streamline account management and improve client interactions. Drive innovation and efficiency while supporting a...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $140K *

Unlock potential by transforming complex data into actionable insights that drive strategic decision-making. Collaborate with stakeholders to develop advanced analytics solutions and maintain high-qua...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$252K - $301K *

Transform patient care by managing diverse needs in a collaborative environment. Engage in acute, chronic, and well visits, utilizing your clinical expertise while supervising colleagues and embracing...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$252K - $301K *

Join a team that's dedicated to transforming primary care by managing diverse patient needs, conducting in-office and tele-health visits, and collaborating with clinical teams to enhance patient outco...

Boston, MARemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$170K - $230K *

Reimagine the Pro experience by leading product strategy and execution. Collaborate across teams to enhance installation, management, and diagnostics for HVAC professionals, driving measurable outcome...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$67K - $94K *

Champion sales growth by leading merchandising, pricing, and inventory strategies. Drive community outreach and enhance customer engagement while ensuring high service standards and operational excell...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$111K - $167K *

Elevate community health by providing expert pharmaceutical care, ensuring compliance, and fostering patient relationships. Lead pharmacy operations while mentoring a dedicated team to enhance service...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Take ownership of designing and implementing AI-powered commerce solutions, ensuring scalable and secure deployments. Collaborate with clients to align AI strategies with business goals while optimizi...

Yesterday

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.