Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$110K - $218K *

Join a team that's driving transformation through Oracle Cloud Financials. Collaborate with clients to gather requirements, design processes, and implement solutions that enhance efficiency and decisi...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$135K - $150K *

Analyze and support complex systems engineering processes for defense programs, ensuring compliance with specifications and enhancing system performance through comprehensive evaluations and technical...

Yesterday

  •   11 - 15 years exp.  •   Aerospace & Defense

$250K - $350K *

Lead the charge in driving business development and executing strategic transactions. Oversee a team while advising clients on mergers and acquisitions, ensuring timely deliverables and fostering clie...

Yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$250K - $350K *

Strategize and lead business development initiatives while overseeing transaction execution and mentoring a dynamic team. Drive measurable revenue results through client engagement and strategic advis...

Yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$143K - $194K *

Join a team that drives the execution of integrated media plans, ensuring compliance and operational excellence. Collaborate with cross-functional teams while enhancing brand strategies in healthcare...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive complex, multimillion-dollar IT programs with global impact, collaborating with C-suite leaders. Lead cross-functional teams to achieve strategic objectives, ensuring accountability and measurab...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$99K - $144K *

Unlock impact in liver disease research by leading a multidisciplinary team to develop therapies for PSC. Collaborate with global experts, manage operations, and drive funding and awareness strategies...

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$86K - $208K *

Join a Magnet-designated hospital as an IR RN, providing exceptional patient care in a dynamic environment. Enjoy competitive compensation, comprehensive benefits, and opportunities for professional g...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$68K - $105K *

Transform your career by configuring and supporting Epic applications. Engage in systems analysis, design, and problem resolution while collaborating with end-users to enhance their experience and str...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$86K - $208K *

Elevate patient care by leading interventional nursing practices in a Magnet-designated facility. Collaborate with a dedicated team to provide exceptional clinical support and ensure high standards of...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Join a team that shapes global regulatory strategy in a fast-paced environment. You will lead comprehensive regulatory plans, ensuring alignment and execution from development to post-marketing, impac...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Partner with us to oversee multiple construction projects, manage budgets, and build client relationships. Your expertise will ensure timely and cost-effective project completion while providing techn...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a team that's focused on driving partner growth in the travel industry. Leverage your expertise to build relationships, implement strategic plans, and engage clients, all while thriving in a coll...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Elevate veterinary care by leading a dedicated team, enhancing patient outcomes, and fostering a collaborative culture. Shape the future of our hospital while maintaining an active clinical role and m...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Drive operational excellence by owning the Professional Services intake and workflow governance processes, ensuring efficient request management and seamless team collaboration to enhance service deli...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Shape the future of talent acquisition by managing end-to-end recruitment processes, collaborating with cross-functional teams, and optimizing hiring strategies to attract top talent in a fast-paced e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$100K - $120K *

Engage with government agencies to drive revenue through strategic partnerships. Cultivate relationships, identify opportunities, and execute sales strategies to meet growth objectives in the Intellig...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$100K - $131K *

Reimagine your career by joining our team as a Senior Application Security Engineer. In this hands-on role, you'll enhance software security across digital platforms, collaborating with development te...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $92K *

Elevate student success by providing tailored mathematics instruction for students with disabilities. Collaborate with educators and families to develop and implement effective IEPs, ensuring every le...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Advance your career by delivering impactful behavioral analysis and supervision. Collaborate with families and staff to enhance treatment plans while managing a small caseload in a supportive environm...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$131K - $237K *

Unlock potential by driving business growth in the cruise missile sector, engaging with U.S. Navy and Marine Corps stakeholders to identify and capture new opportunities while collaborating with cross...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Technical Services

$100K - $231K *

Drive innovation in clinical decision support by leading the development of an AI-powered insights platform. Collaborate with cross-functional teams to transform complex data into actionable solutions...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$83K - $222K *

Champion the development of innovative data solutions in a dynamic team, leveraging modern technologies to enhance healthcare delivery. Collaborate with cross-functional teams to design, implement, an...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$216K - $235K *

Drive Pharmaceutical Development initiatives by overseeing CDMO activities, ensuring alignment across teams, and managing operational planning to support drug development programs effectively and effi...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's shaping competitive electrical bids, ensuring alignment with customer needs and organizational standards while enhancing the customer experience across our electrification division...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.