Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,893

Sort By: Relevance

$110K - $130K *

Unlock potential by developing advanced simulation software for the National Airspace System. Collaborate across teams to model aircraft trajectories, weather, and ATC behavior, utilizing your experti...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Transform insights into impactful strategies by leading market research projects, collaborating with account teams, and delivering compelling narratives that drive client decisions and foster long-ter...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$150K - $200K *

Pioneer client relationships with high-net-worth individuals, driving growth through advanced planning strategies. Collaborate in a team environment to enhance client outcomes and expand assets under...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$104K - $117K *

Engage with senior technical requisitions, ensuring quality outreach and swift hiring. Collaborate with executives, utilize AI tools, and uphold communication standards to attract top talent in a comp...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Empower clients by leading data transitions to e-Automate, ensuring timely, high-quality implementations. Collaborate with teams to enhance processes and deliver tailored solutions that meet diverse b...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $93K *

Elevate grant management and database oversight for innovative rural health programs. Collaborate with stakeholders to ensure compliance and reporting, while driving project success through meticulous...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in transforming our DevOps Platform Engineering team, driving innovative solutions and best practices to enhance cloud and on-premise infrastructure, while collaborating with cross-fun...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $170K *

Lead the charge in managing complex real estate transactions, collaborating with brokerage teams to secure optimal deal terms while developing strategic plans that align with client goals and drive op...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $125K *

Manage environmental projects by overseeing permitting, compliance, and field investigations. Collaborate with multidisciplinary teams to ensure project success across transportation, energy, and land...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $120K *

Empower client success by managing relationships and delivering tailored insurance solutions. Collaborate with internal teams to enhance client experiences, drive retention, and support strategic init...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$122K - $183K *

Lead a team to optimize Medicare Advantage data submissions, ensuring accuracy and compliance. Collaborate across departments to enhance reporting processes and drive operational efficiencies while ma...

Today

  •   5 - 7 years exp.  •   Healthcare

$165K - $194K *

Pioneer impactful scientific exchanges as a Senior Medical Science Liaison, fostering relationships with healthcare providers and key opinion leaders in hematology/oncology while supporting Rigel's in...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$143K - $243K *

Lead full-stack development initiatives, combining hands-on engineering with technical leadership to enhance clinical workflow solutions. Collaborate across teams to deliver scalable, reliable softwar...

Today

  •   5 - 7 years exp.  •   Healthcare

$91K - $120K *

Champion patient care by providing direct support and assessments as a key member of a multidisciplinary team, ensuring a safe therapeutic environment and contributing to treatment plans that enhance...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Elevate the delivery of Salesforce programs by leading end-to-end project management, ensuring compliance, and fostering collaboration across teams to enhance federal application modernization efforts...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Join a dynamic team where you'll take ownership of key Corporate Performance Management projects, executing tasks from build to testing, while collaborating with clients and delivering high-quality wo...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$70K - $95K *

Drive patient relationships by conducting consultations and crafting tailored treatment plans. Collaborate with clinicians to ensure a premium experience, while achieving personal revenue targets thro...

Today

  •   Less than 5 years exp.  •   Healthcare

$83K - $95K *

Support high-quality imaging and clinical duties in a fast-paced urgent care setting. Collaborate with providers to deliver timely patient care while performing diagnostic radiology exams and assistin...

Today

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Collaborate with brokers and clients to drive profitable business through expert underwriting of complex accounts. Leverage strategic insights and relationship-building to optimize portfolio performan...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $185K *

Lead the strategy and development of innovative analytics and AI solutions, collaborating with cross-functional teams to transform complex healthcare data into actionable insights that drive measurabl...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$210K - $280K *

Shape the future of quantitative investment research by leading innovative modeling and analysis for private markets. Collaborate with diverse teams to generate actionable insights that enhance invest...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$87K - $123K *

Drive the reliability and performance of a cutting-edge research platform. Collaborate with teams to enhance operational tooling, automate processes, and ensure system dependability as user needs evol...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$133K - $249K *

Drive acquisition lifecycle support and strategic evaluations in M&A. Collaborate with cross-functional teams to conduct data analyses, monitor competitor activities, and enhance the investment thesis...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive operational excellence by leading strategic initiatives, enhancing client partnerships, and fostering a high-performing team in a rapidly evolving security services environment. Shape the future...

Reposted today

  •   5 - 7 years exp.  •   Staffing

$110K *

Empower a dynamic mobile team by providing 24/7 AOG support, coordinating maintenance events, and ensuring regulatory compliance while fostering strong customer relationships and maintaining operation...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.