Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,901

Sort By: Relevance

$150K - $180K *

Champion the growth of our commercial engine by leading business development efforts, forging strategic partnerships, and driving revenue as quantum computing transitions to enterprise applications. C...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$73K - $99K *

Deliver high-quality patient care by conducting triage, performing clinical procedures, and collaborating with the healthcare team. This role offers opportunities for professional growth in a supporti...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $185K *

Architect comprehensive clinical supply strategies for global trials. Collaborate across functional teams to secure timely, compliant drug supply while managing risks and inventory effectively, ensuri...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Drive operational excellence in commercial readiness and support cross-functional teams to ensure effective execution of launch strategies and operational priorities in a dynamic biotech environment...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Champion mobile and web application development, SQL reporting, and ERP support. Collaborate across technologies to enhance efficiency and solve business challenges. Ideal for a hands-on developer eag...

Reposted today

  •   5 - 7 years exp.  •   Food & Beverages

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$92K - $139K *

Elevate customer success by managing a portfolio of enterprise accounts, ensuring optimal software utilization, and fostering strong relationships. Collaborate with clients to solve complex challenges...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$83K - $138K *

Lead the strategy and performance management for our mobile app and loyalty experience, driving athlete engagement and revenue growth through cross-functional collaboration and data-driven insights. O...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Join a team that's redefining product marketing by leading impactful go-to-market strategies, enabling sales teams, and shaping customer insights to drive success in a fast-paced B2B SaaS environment...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$132K - $207K *

Elevate your career by driving growth in the mortgage industry, partnering with top lenders to enhance FICO's analytics solutions. Lead strategic initiatives, foster client relationships, and deliver...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$62K - $110K *

Join a dynamic team as you support the treatment and rehabilitation of adolescent males in a secure residential program, enhancing their growth and coping skills while promoting their mental and physi...

Today

  •   Less than 5 years exp.  •   Healthcare

$200K - $225K *

Transform marketing strategies to drive growth and engagement across public and private sectors. Lead integrated marketing efforts, brand positioning, and customer marketing services while leveraging...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$166K - $225K *

Empower Amazon's operations by owning product strategy and roadmap, ensuring self-service technology for frontline teams. Collaborate with engineering to enhance device management and operational effi...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$107K - $176K *

Unlock potential by driving HR transformation initiatives that enhance client relationships and deliver measurable business value. Collaborate with stakeholders to optimize HR processes and mentor jun...

Today

  •   Less than 5 years exp.  •   Business Services

$166K - $225K *

Shape the future of Amazon's operations by owning product strategy and roadmap. Collaborate with engineering teams to enhance device management, ensuring reliability and efficiency across global fulfi...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$125K - $135K *

Transform the biopharmaceutical landscape by addressing strategic questions, conducting complex analyses, and collaborating with a dynamic team to deliver impactful solutions in life sciences consulti...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $93K *

Join our team to troubleshoot, repair, and install CNC machines while ensuring operational excellence and customer satisfaction through effective communication and advanced technical expertise...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$157K - $256K *

Shape strategic pricing and channel strategies for innovative therapies, ensuring patient access and affordability. Lead cross-functional initiatives, optimize distribution models, and drive market in...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$85K *

Join a team that's dedicated to ensuring compliance in global medical device registrations. You'll execute regulatory strategies, prepare essential documents, and collaborate with cross-functional tea...

Today

  •   Less than 5 years exp.  •   Healthcare

$158K - $285K *

Champion the technical ownership of laboratory computing systems, ensuring reliability, security, and compliance. Collaborate across teams to enhance workflows and integrate innovative technologies, d...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$272K - $431K *

Lead the charge in architecting and scaling data acquisition infrastructure for foundation models. Collaborate across teams to enhance web crawling, ingestion, and data quality, ensuring reliable, hig...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$120K - $182K *

Accelerate growth by driving new software sales, building client relationships, and tailoring solutions to meet unique business needs. Collaborate with cross-functional teams to ensure a seamless cust...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Deliver expert pharmacy services while mentoring a collaborative team. Engage with patients to provide medication education, ensure safety, and advance healthcare solutions in a dynamic retail environ...

Brockton, MAIn-Person

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $200K *

Join us to lead a dynamic marketing strategy focused on growth and demand generation. Oversee a talented team, manage budgets, and drive innovative marketing initiatives across B2B, B2C, and patient s...

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Drive major gift fundraising efforts by managing a portfolio of high-capacity donors, cultivating relationships, and securing six-figure gifts. Collaborate with leadership to enhance donor engagement...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.