Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$252K - $336K *

Drive the adaptation of advanced AI models to meet customer-specific needs, ensuring reliable workflows and high-quality outputs through expert post-training and evaluation techniques in a collaborati...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$128K - $198K *

Join a team that drives the future of superconductivity by developing and implementing advanced characterization workflows. Collaborate with experts in materials science and AI to accelerate high-thro...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $108K *

Champion customer success by providing expert technical support for bioprocessing products. Collaborate with teams to troubleshoot issues, enhance documentation, and drive resolutions, ensuring a seam...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $108K *

Empower customer success by providing expert technical support for bioprocessing products. Collaborate with teams to troubleshoot issues, enhance product knowledge, and ensure a positive experience fo...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K - $184K *

Drive operational excellence by leading physician practices in Ohio. Collaborate with clinical and regional teams to enhance performance, accountability, and patient experience while translating data...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Elevate quality assurance standards by developing and implementing effective QAPI programs. Collaborate with teams to identify improvement areas, conduct evaluations, and ensure compliance with health...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $126K *

Shape the future of our fleet operations by supervising teams, ensuring safety compliance, and optimizing maintenance processes. Lead a dedicated workforce to achieve financial targets while fostering...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$171K - $274K *

Lead and elevate a high-performing program management team, enhancing execution discipline and visibility across complex product-development initiatives while collaborating with cross-functional teams...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $160K *

Join a team that's developing innovative semiconductor test equipment. Take ownership of complex engineering challenges, collaborating across disciplines to deliver high-quality designs that meet mark...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $135K *

Solve complex marketing challenges by leveraging data science techniques. Build predictive models, analyze big data, and communicate insights to drive strategic decisions across diverse client applica...

1 week ago

  •   Less than 5 years exp.  •   Media

$171K - $274K *

Join a dynamic team to lead program management, enhance execution discipline, and drive visibility across complex engineering initiatives while fostering a high-performing culture and stakeholder alig...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$140K - $228K *

Lead the charge in enhancing cybersecurity by driving detection engineering, incident response, and automation. Collaborate cross-functionally to secure cloud architectures and improve operational eff...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$225K - $281K *

Lead the charge in shaping detection and response strategies, driving hands-on initiatives to enhance security architecture and incident management. Collaborate across teams to ensure robust threat de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $100K *

Join a dynamic ICU team, managing critically ill patients with advanced care techniques. Utilize your expertise in telemetry and critical interventions to provide exceptional patient support in a fast...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $100K *

Transform enterprise sales by driving full-cycle processes, building multi-stakeholder relationships, and leveraging AI tools to achieve quota and deliver impactful solutions to large organizations...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $192K *

Engage healthcare providers and drive commercial performance in a defined territory. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative therapi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $135K *

Lead the charge in developing precise asset-level forecasts and models for North American power markets. Conduct in-depth research and provide critical insights while mentoring junior analysts and bri...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $170K *

Engage in dynamic civil litigation as an Associate Attorney, managing cases from inception to resolution. Collaborate with clients and colleagues while honing your advocacy skills in a supportive, hyb...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Transform brand vision into cohesive creative suites across digital and print. Collaborate with cross-functional teams to deliver engaging designs that enhance customer experience and uphold brand sta...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a team that's transforming software sales by driving technical solutions and creative outreach. Lead the full sales cycle and collaborate cross-functionally to deliver unique insights and busines...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$117K - $201K *

Optimize biologics discovery by integrating AI and computational design into therapeutic programs. Collaborate across teams to enhance decision-making and accelerate learning cycles, shaping the futur...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $270K *

Join a team pioneering AI/ML platform engineering, enhancing scalable infrastructure to empower scientific innovation. Shape the future of distributed systems and MLOps, collaborating across teams to...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $180K *

Champion the use of innovative medical technology by training and supporting clinical staff in the effective application of the Globe PF System, ensuring successful clinical trials and enhancing patie...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Innovate your career by forming executive relationships and leading complex sales cycles. Drive value through consultative engagements, leveraging insights to elevate conversations with senior leaders...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Champion workplace safety by developing and implementing health and safety programs. Ensure compliance with regulations, conduct inspections, and lead training initiatives to foster a culture of safet...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.