Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$92K - $160K *

Elevate the FutureChoice service model by driving transformation initiatives, assessing impacts, and fostering cross-functional collaboration to enhance customer journeys and operational effectiveness...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Transform virtual primary care by delivering exceptional patient care in a collaborative environment. Join a dedicated team for a 5-month full-time opportunity, enhancing your skills while making a me...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$153K - $268K *

Join our team to provide expert clinical pharmacology insights, driving dose selection and study design for innovative therapies. Collaborate with cross-functional teams to translate complex data into...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $182K *

Join a team that's at the forefront of cybersecurity innovation, tackling complex challenges in software and embedded systems security. Collaborate with experts to develop cutting-edge solutions and p...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$145K - $220K *

The Full Spectrum Cyber Capability and Operations Expert will develop and implement novel cyber capabilities for unconventional devices and networks, focusing on the intersection of cybersecurity and...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$145K - $220K *

Lead the charge in designing innovative space electronics systems that meet national security needs. Collaborate with diverse teams, mentor junior engineers, and ensure excellence in cutting-edge elec...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$116K - $182K *

Drive the development of next-generation radar systems, collaborating with multidisciplinary teams to innovate and prototype solutions that enhance space surveillance capabilities in support of nation...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$145K - $220K *

Join us to design and implement cutting-edge satellite communications technologies, collaborating with experts to advance systems for robust communication capabilities...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$145K - $220K *

Drive the development of AI/ML applications in weather and Earth systems, focusing on dataset procurement, algorithm training, and model integration. Collaborate on innovative solutions to enhance env...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$86K - $103K *

Lead the charge in optimizing programmatic media campaigns across channels, leveraging your marketing expertise to enhance client relationships and drive strategic execution while managing budgets and...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $182K *

Explore innovative software solutions for next-gen transportation systems while collaborating with experts to design, develop, and document decision support systems. Engage in full-stack development a...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$260K - $300K *

Join a team that's redefining educational partnerships! As a key leader, you'll drive strategic collaborations that enhance student success and foster sustainable relationships, shaping impactful solu...

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$116K - $182K *

Join us in developing innovative RF systems, integrating cutting-edge technologies, and testing prototypes in lab and real-world environments to advance communication and sensing capabilities...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $192K *

Grow your career by engaging healthcare providers and driving commercial success. Collaborate with cross-functional teams to support product launches and enhance patient access to innovative therapies...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Join a team that's pivotal in driving commercial performance and product adoption. Engage healthcare providers, build relationships, and support innovative therapies while collaborating with cross-fun...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$68K - $106K *

Shape operational excellence in primary care by leading strategic initiatives, optimizing workflows, and enhancing patient experiences. Collaborate with clinical leaders to drive performance and ensur...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and enhance patient access to innovativ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $187K *

Join a team that's dedicated to optimizing strategic partnerships and enhancing service excellence. Lead a skilled team to manage vendor relationships, drive process improvements, and ensure top-tier...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $130K *

Optimize procurement processes by leading vendor negotiations, managing contracts, and implementing frameworks that ensure cost-effective spending across the organization while fostering strong vendor...

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$120K - $130K *

Unlock your potential by engaging with clinical and technical teams to enhance radiology workflows. Drive customer interest through expert product demonstrations and support sales initiatives, ensurin...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$205K - $427K *

Empower transformation by leading large-scale enterprise programs in Life Insurance and Annuities. Drive strategic initiatives, foster executive relationships, and oversee multi-disciplinary teams to...

1 week ago

  •   11 - 15 years exp.  •   Business Services

$134K - $265K *

Lead transformative initiatives in investment management, focusing on risk assessment, operational efficiency, and innovative technologies like tokenization and AI. Collaborate with clients and teams...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Empower strategic growth by managing key accounts across diverse sectors. Drive revenue, enhance client relationships, and deliver integrated solutions while collaborating with global teams to ensure...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$274K - $371K *

Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.