Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,897

Sort By: Relevance

$242K - $332K *

Champion innovative AI solutions to enhance investment strategies and decision-making through partnership with investment teams and engineering. Lead the delivery of effective tools that align technol...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $200K *

Transform your career by driving wealth management growth across the Pacific West. Collaborate with advisors and leaders to enhance product adoption and sales, leveraging market insights and relations...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$60K - $110K *

Deliver exceptional sales performance by developing strategies, building relationships, and maximizing opportunities within your territory while adhering to industry regulations and corporate standard...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$126K - $227K *

Lead the charge in manufacturing excellence by providing expert DFM and NPI support. Collaborate with teams to resolve technical issues, enhance processes, and drive continuous improvement while ensur...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$142K - $195K *

Champion transformative enterprise architecture initiatives that align technology with business strategy, driving innovation and modernization across healthcare payer domains to enhance operational ef...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$126K - $173K *

Champion the development of Provider Direct Connect capabilities, driving product vision and strategy while collaborating with cross-functional teams to enhance provider engagement and deliver scalabl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Elevate Medicare Advantage performance by delivering financial analysis and insights. Collaborate with cross-functional teams to drive operational excellence and support strategic initiatives, while l...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Advance your career by leading strategic partnerships, optimizing relationships, and driving revenue growth. Collaborate across teams to enhance product capabilities and market reach while managing a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$176K - $294K *

Unlock potential by leading strategic initiatives in Medical Affairs, enhancing operational excellence, and fostering collaboration across teams to drive impactful medical plans and stakeholder engage...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$274K - $457K *

Shape the future of clinical development by leading cross-functional teams, guiding global projects, and driving innovative strategies for regulatory submissions and drug approval in Internal Medicine...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Lead the charge in managing high-complexity projects, overseeing resources, and driving innovation across the Global Business Unit to solve complex problems and achieve strategic objectives. Promote c...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$176K - $294K *

Drive medical strategies for Sickle Cell Disease, collaborating with cross-functional teams to enhance patient care and support clinical initiatives. Lead advisory boards and engage with thought leade...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$274K - $457K *

Shape the future of hematology clinical development by leading study teams, ensuring regulatory compliance, and guiding strategic initiatives. Your expertise will shape innovative therapies that signi...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$230K - $384K *

Optimize medical strategies in Sickle Cell Disease by collaborating with cross-functional teams, leading initiatives, and building relationships with thought leaders to enhance patient care and suppor...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$176K - $294K *

Lead and coordinate clinical studies for innovative therapies, ensuring collaboration across teams and driving successful study execution while contributing to drug development activities and maintain...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $176K *

Shape the future of biologic therapeutics by leading innovative research in computational antibody design, utilizing advanced machine learning techniques to optimize drug discovery and enhance therape...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$274K - $457K *

Accelerate innovative clinical development strategies while leading cross-functional teams. Foster collaboration to ensure timely regulatory submissions and optimal trial execution within the internal...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$189K - $315K *

Lead the charge in transforming Oncology Field Access & Reimbursement strategies, coaching a dedicated team to enhance patient access and engagement across the East region while ensuring compliance an...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$274K - $456K *

Drive the future of Inflammation & Immunology by leading evidence strategy and cross-functional execution to enhance product impact and patient outcomes through innovative research and partnerships...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$230K - $384K *

Drive analytics excellence by leading cross-functional teams to define care gap models, manage stakeholder engagement, and deliver impactful insights that shape strategic decisions in the healthcare l...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$106K - $176K *

Support the execution of clinical studies for small molecule and biological therapies, collaborating with cross-functional teams to ensure timely enrollment and delivery. Contribute to study documenta...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$230K - $384K *

Shape the future of medical engagement by leading omnichannel strategies across therapeutic areas. Collaborate with cross-functional teams to enhance communication with healthcare professionals and op...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$144K - $205K *

Lead the charge in enhancing AP World Languages and Arts by ensuring assessment quality, driving strategic growth, and managing a diverse team. Collaborate with leadership to influence enterprise deci...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$144K - $205K *

Elevate the quality and impact of AP Social Science courses by leading a diverse team, driving strategic initiatives, and ensuring assessment integrity. Collaborate across departments to enhance stude...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$155K - $210K *

Drive market growth by leading product strategy and execution for innovative solutions in semiconductor automation, ensuring customer value and profitable share expansion through effective collaborati...

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.