Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.
Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.
Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.
Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.
Average Salary: $125,896
$100K - $500K+*
Join a dynamic team as you build trusted relationships, conduct in-home inspections, and provide tailored solutions for homeowners. Leverage industry-leading training and technology to drive your sale...
Today
$80K - $95K *
Support financial analysis and reporting for global operations, collaborating with cross-functional teams to enhance insights and streamline processes across manufacturing networks in North America, E...
Today
Director, Digital Product Management
$174K - $255K *
Unlock your potential as a senior product leader driving digital growth strategies. Shape product vision and multi-year roadmaps to enhance customer engagement and revenue across diverse channels in a...
Reposted today
Product Manager (2x YC founder mentorship)
$130K - $160K *
Elevate your career by joining a dynamic team where ownership, urgency, and resilience drive success. Collaborate closely with executives in a fast-paced environment, tackling challenges and mastering...
Today
Product Manager-in-Training (YC cofounder/CEO-led)
$130K - $160K *
Advance your career by learning product management directly from a CEO. Engage with diverse teams in a fast-paced startup, tackling real-world challenges and developing strategies that drive growth an...
Today
Senior Specialist, Regulatory Operations
$122K - $143K *
Innovate regulatory operations by managing submission preparation and execution, ensuring compliance with FDA and ICH standards. Collaborate cross-functionally to support complex filings and maintain...
Today
Senior Research Scientist I, Antibody Engineering and Characterization
$110K - $130K *
Transform biologics drug discovery by leading antibody engineering campaigns, optimizing therapeutic formats, and collaborating across teams to advance innovative solutions from concept to candidate n...
Today
Account Manager, DNA Synthesis - SouthEast
$100K - $120K *
Drive revenue growth by managing key customer relationships and delivering accurate forecasts. Collaborate with teams to support product development and ensure compliance with industry standards while...
Today
Resident Engineer (Civil Engineer III)
$80K - $95K *
Pioneer engineering excellence by overseeing construction projects, ensuring compliance with standards, and managing documentation. Collaborate with teams to deliver high-quality infrastructure soluti...
Today
Senior System Integration & Test (I&T) Engineer
$110K - $130K *
Shape the future of advanced RF systems integration and testing. Collaborate with experts to ensure seamless hardware and software functionality, leveraging cutting-edge tools and methodologies in a d...
Today
Senior Director, Clinical Operations Strategy
$160K - $200K *
Innovate operational excellence in Clinical Operations by leading strategic initiatives, workforce planning, and cross-functional alignment to drive organizational effectiveness and support clinical d...
Today
Hourly FFS - Outpatient Therapist
$93K - $114K *
Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while making a meaningful impact in the lives of individual...
Today
Associate, Strategic Finance & Corporate Development
$115K - $140K *
Reimagine financial strategy as you drive analytical rigor and strategic clarity in a high-impact role. Collaborate with cross-functional teams to support growth initiatives and shape the future of a...
Today
Outpatient Mental Health Therapist - Hybrid Position
$62K - $112K *
Join a team of enthusiastic mental health professionals dedicated to transforming the sector by enhancing access and care quality, ensuring both client and clinician satisfaction in a supportive, grow...
Reposted today
$164K - $262K *
Take ownership of software architecture and development to create scalable, user-centric applications. Lead comprehensive development initiatives while optimizing performance and mentoring engineers i...
Reposted today
Psychiatric Nurse Practitioner (PMHNP)
$200K - $257K *
Join our dynamic team to provide exceptional mental health care through a hybrid model, combining telehealth and in-office support. Collaborate with dedicated professionals while enjoying flexible sch...
Today
Senior System Software Engineer - Datacenter Power Management
$224K - $431K *
Innovate cutting-edge software for data center power management, spanning architecture, firmware, and AI workloads. Drive product lifecycle from design to deployment, enhancing performance and energy...
Today
$86K - $99K *
Champion aggressive sales growth by building strategic relationships and generating leads in the insurance housing sector. Drive market share expansion through effective communication and innovative s...
Today
Digital Content Senior Communication Specialist
$97K - $121K *
Join a team that's driving digital engagement through innovative content creation and strategic social media campaigns. This role demands agility and creativity to enhance brand presence across multip...
Today
$70K - $118K *
Unlock potential by managing inventory processes across multiple locations, leading a team of 15-25, and ensuring accurate counts and audits. Drive operational excellence while coordinating with third...
Reposted today
$73K - $109K *
Lead daily transportation operations for our Medical Waste Division, focusing on efficiency, compliance, and customer satisfaction. Manage drivers, dispatch, and route planning while promoting safety...
Today
$70K - $118K *
Elevate inventory management by leading a team to ensure accurate counts and audits across multiple supply chain locations, while optimizing processes and maintaining operational excellence through ef...
Reposted today
$110K - $130K *
Empower your career by driving strategic sales initiatives within large healthcare organizations. Own the full sales cycle, build executive relationships, and position a leading clinical collaboration...
Today
$87K - $157K *
Transform the Naval Enterprise Network through Model-Based Systems Engineering, utilizing SysML and CSM tools to develop and manage system models, requirements, and designs while collaborating with st...
Today
$107K - $195K *
Unlock your potential as an Energy Market Analyst, driving insights and strategies for clients in the North American power sector. Collaborate on market projections, asset valuations, and innovative s...
Today
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.
Where can I find professional jobs in Massachusetts?
Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.
Are the Massachusetts jobs on Ladders vetted?
Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.
How can I find a Massachusetts job that matches my experience?
Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.