Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,902

Sort By: Relevance

$63K - $99K *

Empower the Product Category Management team by analyzing data trends, generating reports, and supporting strategic decisions. Collaborate across departments to enhance product performance and mentor...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $95K *

Unlock potential by providing strategic business analysis and project management expertise. Collaborate with stakeholders to enhance processes, ensure data integrity, and deliver impactful business so...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$467K - $500K+*

Provide advanced surgical care for heart failure and transplantation, collaborating with multidisciplinary teams to enhance patient outcomes in a leading cardiovascular center, focusing on innovative...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $138K *

Elevate patient safety by leading risk management initiatives, ensuring compliance, and fostering a culture of safety across all clinical settings. Collaborate with diverse teams to identify, analyze...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $222K *

Drive innovation by designing and implementing digital solutions that optimize Payer Operations, enhance metadata, automate contracts, and measure performance through collaboration and advanced techni...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Transform the future of AI governance by leading enterprise strategy, ensuring compliance, and managing risks across the AI lifecycle. Collaborate with cross-functional teams to implement responsible...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$180K - $215K *

Unlock potential by leading regional sales efforts for a groundbreaking product. Drive performance through strategic execution, team leadership, and customer engagement in a fast-paced, entrepreneuria...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive HR operations and total rewards initiatives, enhancing employee experiences and optimizing processes. Collaborate with teams to leverage data and technology, ensuring compliance and delivering i...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Develop and lead regional strategies to drive product launch success, ensuring alignment with corporate goals. Build a high-performing team, foster customer relationships, and execute data-driven deci...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $240K *

Join a dynamic team as you provide technical expertise, drive enterprise opportunities, and architect innovative solutions that meet client needs while showcasing the value of our cutting-edge product...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$188K - $228K *

Champion innovative biostatistical methods in clinical trials, collaborating with cross-functional teams to design studies, analyze data, and prepare regulatory submissions, ensuring high-quality resu...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$67K - $111K *

Deliver compassionate, expert behavioral health care throughout members' journeys, ensuring clinical excellence in a fast-paced, 24/7 environment as a trusted clinical partner in diverse cases and sup...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $240K *

Grow your career with a pivotal role leading HR for M&A activities, ensuring seamless integration and alignment of people strategies across global transactions while advising senior leaders in a dynam...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $240K *

Join a team that's redefining M&A success by leading HR integration and due diligence efforts. You'll partner with cross-functional leaders to assess risks, drive cultural alignment, and ensure seamle...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$177K - $278K *

Champion innovative patient recruitment strategies to enhance clinical trial engagement and retention. Lead a dynamic team, leveraging data and technology to optimize enrollment across diverse therape...

Massachusetts, USRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $130K *

Join a dynamic team to design and optimize scalable data solutions that enhance healthcare technology platforms. Collaborate with cross-functional teams to ensure data integrity and drive informed dec...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$92K - $105K *

Unlock potential by driving sales of innovative additive manufacturing solutions. Engage with clients, identify needs, and deliver tailored solutions while enhancing customer satisfaction and contribu...

6 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Unlock potential by designing cutting-edge silicon MMIC circuits, collaborating with teams to validate models, and supporting product development from conception to release. Join us in advancing techn...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $157K *

Engage a dynamic team to deliver exceptional fund accounting and administration services, ensuring compliance and client satisfaction while driving innovative technology solutions and managing complex...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $140K *

Lead and execute complex audits across Global Treasury, focusing on liquidity and interest rate risks. Manage audit teams, ensure quality, and communicate findings to senior management while maintaini...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $157K *

Unlock potential by leading a dynamic team in fund accounting and administration, ensuring client satisfaction while managing complex financial services for alternative investments. Drive innovation a...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $132K *

Join a team that's redefining social media strategy and content. Lead the charge in crafting a modern social vision that enhances brand engagement, drives cultural relevance, and builds a dynamic cont...

6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$63K - $105K *

Champion the development of AI agents and workflows, leveraging GenAI.mil to create innovative automated solutions. Collaborate with cross-functional teams to enhance processes and deliver high-qualit...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $172K *

Elevate patient care by joining a dynamic team that empowers pharmacists to utilize their clinical expertise, engage with customers, and ensure compliance while enhancing community health initiatives...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.