Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$127K - $169K *

Champion the optimization of drug therapy by resolving drug-related issues and enhancing therapeutic outcomes. Lead pharmacy services, ensure compliance with regulations, and contribute to quality imp...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$126K - $180K *

Lead the charge in shaping cloud infrastructure by collaborating with teams to enhance platform architecture, ensure availability, and mentor engineers, all while driving innovation in AI capabilities...

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$118K - $147K *

Join our dynamic MEP/FP team to lead plumbing design for diverse projects, ensuring high-quality deliverables and technical consistency while mentoring engineers and coordinating with multidisciplinar...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $200K *

Empower our growth by managing the positioning, messaging, and GTM strategy across multiple industries, ensuring impactful narratives that resonate with diverse stakeholders and drive revenue growth t...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Drive your career by owning the go-to-market strategy for our AI Agent platform. Collaborate with cross-functional teams to create compelling narratives and enable sales, while launching innovative pr...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $173K *

Lead strategic growth initiatives and optimize operations to enhance customer value. Collaborate with cross-functional teams to drive compliance, monitor KPIs, and ensure operational excellence across...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$100K - $120K *

Join a team that's shaping the future of AI research and policy. As a Research Manager, you'll lead interdisciplinary projects, mentor junior researchers, and collaborate with experts to drive impactf...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Elevate talent management by leading strategic initiatives that enhance employee growth, performance, and retention. Collaborate with leadership to implement integrated practices across the employee l...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead strategic sales initiatives across diverse sectors, driving growth by cultivating relationships and delivering tailored solutions. Manage a territory, engage with partners, and achieve sales goal...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $135K *

Architect robust identity and access systems, ensuring seamless integration and security across multi-cloud environments. Drive automation and compliance initiatives while collaborating with cross-fun...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Champion systems engineering by designing and managing identity, infrastructure, and security systems. Collaborate across teams to ensure automation, compliance, and productivity in a fast-paced envir...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Champion innovative analytical strategies for biologics development, ensuring robust control and compliance. Collaborate cross-functionally to drive project success and optimize methodologies in a dyn...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$16K - $182K *

Join a team that's building innovative backend services and APIs for talent matching, leveraging AI tools to enhance candidate experiences. Collaborate with Data Science to ensure reliable, high-perfo...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Advance sales growth by developing key relationships in the solar industry. Drive strategic initiatives across the Eastern U.S. while managing complex sales processes and collaborating with internal t...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $185K *

Lead the charge in operational excellence and market growth by managing compliance, program execution, and cross-functional collaboration to drive customer success and engineering alignment across key...

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$83K - $91K *

Empower compassionate nursing care by delivering quality support to residents. Collaborate with a dedicated team to enhance community well-being and foster meaningful relationships in a nurturing envi...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Elevate your career by driving revenue growth and strategic partnerships within a leading Oracle practice. Lead cross-functional teams to enhance client success and market positioning while fostering...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $185K *

Lead the charge in enhancing quality management systems and compliance for regulated industries. Drive audits, certifications, and AI governance while collaborating across teams to ensure effective pr...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Shape the future of patient access by leading integrated strategies that enhance customer engagement and optimize portfolio performance across diverse healthcare channels, driving sustainable growth a...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$127K - $160K *

Help us shape the future of psychiatric care by conducting evaluations and providing treatment interventions. Collaborate with healthcare teams to enhance patient outcomes and maintain high standards...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $152K *

Advance your career by leading mainframe capacity planning initiatives, optimizing performance, and driving automation solutions. Collaborate with teams to enhance operational efficiency and mentor ju...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$156K - $180K *

Unlock potential by serving as a strategic insights partner, translating market research and analytics into actionable recommendations that drive brand strategy and business planning in the Immunology...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $156K *

Unlock your potential in a collaborative inpatient setting, providing comprehensive care for patients with hematologic and oncologic conditions. Join a dedicated team focused on patient-centered treat...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Shape the future of engineering by delivering innovative solutions and managing complex projects. Collaborate with teams to enhance technical expertise while mentoring junior engineers and ensuring co...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $150K *

Drive innovation by designing and optimizing low-latency teleoperation systems for robotic platforms, enhancing real-time control and communication between operators and robots while collaborating wit...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.