Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$85K - $110K *

Drive business growth by identifying and qualifying federal procurement opportunities, focusing on healthcare contracts. Collaborate on capture strategies and build partnerships to enhance win probabi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Innovate testing and automation systems to enhance software release confidence. Lead technical direction, integrate AI for efficiency, and ensure reliable verification processes while fostering collab...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $117K *

Play a key role in providing advanced technical support for CNC systems, optimizing performance, and collaborating with teams to enhance automation solutions. Engage with customers and partners to res...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $272K *

Lead the charge in driving P&L performance and operational excellence across multiple branches, fostering growth and profitability while building a high-performing team in a dynamic, fast-paced enviro...

6 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Pioneer innovative software solutions for defense programs by leveraging your expertise in C#, .NET, and SQL Server. Collaborate with cross-functional teams to ensure secure, compliant, and high-quali...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$213K - $280K *

Drive LNP formulation and process development, leading a team to establish scalable strategies for diverse applications. Collaborate cross-functionally to ensure high-quality delivery of formulations...

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Elevate your career by validating and modernizing statistical models using SAS and Python. Collaborate with analysts and stakeholders to enhance analytical systems and ensure accuracy in mission-criti...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $150K *

Accelerate growth by managing sales strategies across CA and parts of the Midwest. Lead market development efforts, achieve sales goals, and collaborate with cross-functional teams to enhance customer...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$141K - $177K *

Champion exceptional patient care as a Lead Provider, guiding clinical staff and mentoring new providers in a collaborative urgent care environment, ensuring high-quality health assessments and compli...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $200K *

Unlock your potential by driving new business growth in a dynamic sales role. Engage with customers, build relationships, and develop strategic plans to expand market presence across North and South C...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $120K *

Engage in hands-on laboratory testing and design iteration to enhance system reliability and performance. Collaborate with senior engineers to analyze data, troubleshoot issues, and support regulated...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance strategic marketing and business development initiatives, overseeing sales and customer service efforts. Foster relationships and implement comprehensive strategies to drive growth and revenue...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$141K - $177K *

Lead a dedicated team in delivering exceptional patient care as a clinical mentor. Collaborate with healthcare professionals to enhance service quality and support new providers in a dynamic urgent ca...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a dedicated team to support survivors of trafficking and violence. Manage your own caseload, represent clients in immigration proceedings, and collaborate with legal support staff to ensure effec...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$83K - $114K *

Support patient care by managing home health cases, coordinating services, and collaborating with families. Leverage your nursing expertise to enhance patient outcomes and ensure quality care in a dyn...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Elevate your career by leading civil site projects in the energy sector. Collaborate with a dynamic team to design, coordinate, and manage impactful utility projects while ensuring compliance with loc...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Drive excellence in global clinical study leadership across various therapeutic areas. Collaborate with teams to deliver projects on time and within budget while exceeding client expectations...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock your potential by managing grants and contracts at a leading public health institution. Collaborate with faculty across diverse research areas, ensuring compliance and financial oversight from...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$88K - $105K *

Champion innovative research by managing grants and contracts, ensuring compliance, and collaborating with faculty across diverse public health disciplines to enhance funding opportunities and support...

Boston, MARemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $90K *

Champion exceptional service by leading daily operations and developing a high-performing team. Collaborate with management to ensure a seamless guest experience while maintaining service standards in...

6 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $180K *

Join a team that's redefining the buyer experience in B2B software. As a Principal Product Manager, you'll lead strategy, drive product delivery, and enhance buyer trust across multiple platforms, ens...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $214K *

Lead the charge in user experience research, driving insights that enhance AI product adoption and trust. Collaborate across teams to develop frameworks and metrics that optimize user interactions and...

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$166K - $205K *

Elevate your career as a Senior Medical Science Liaison, driving scientific exchange and collaboration with healthcare providers in oncology. Build relationships, support clinical initiatives, and con...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$161K - $202K *

Unlock potential by leading a dynamic Learning & Development team to enhance clinical and non-clinical training programs, ensuring high-quality patient care through innovative strategies and scalable...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $90K *

Engage with SMB accounts to build pipeline and close value-driven deals. Own your territory, manage sales cycles, and leverage data to drive results. Collaborate across teams to connect solutions with...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.