Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$88K - $154K *

Join a team that's redefining bridge engineering by delivering innovative designs and solutions. Collaborate on diverse projects, ensuring structural reliability and efficiency while enhancing your ex...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$81K - $122K *

Unlock potential by joining our R&D team to enhance wearable medical devices. Collaborate on design, development, and quality processes while supporting product innovation and lifecycle engineering fo...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $150K *

Unlock innovative solutions by collaborating with scientists and stakeholders to translate workflows into technology. This hands-on role combines business analysis and scientific platform administrati...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$152K - $190K *

Champion the future of physical operations by leveraging IoT data to drive business transformation for mid-sized clients. Navigate complex sales processes, engage multiple stakeholders, and educate cu...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$79K - $99K *

Elevate your career by executing and advancing a dynamic organic social strategy. Collaborate with cross-functional teams to create engaging content that resonates with audiences and drives brand rele...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$175K - $220K *

Shape the future of healthcare real estate by leading a dynamic transaction management team. Oversee negotiations, staff development, and strategic planning to drive client success and enhance operati...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$124K - $180K *

Transform research operations by leading a dedicated team to enhance grant management, ensuring compliance and financial stewardship while fostering collaboration across departments to support innovat...

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$83K - $104K *

Elevate your career by providing essential patient care and support in a collaborative environment. Engage with patients, administer treatments, and contribute to their health journey while working un...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $119K *

Join a leading rehabilitation network as an Outpatient Physical Therapist, focusing on pediatric care. Engage in a supportive environment that emphasizes 1:1 treatment, mentorship, and professional gr...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$79K - $115K *

Champion large-scale program management by leading initiatives that align with strategic goals. Oversee project execution, stakeholder collaboration, and budget management while analyzing data and pro...

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$127K - $169K *

Champion the optimization of drug therapy by resolving medication issues and enhancing therapeutic outcomes. Collaborate with healthcare teams to ensure compliance with pharmacy regulations and improv...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$127K - $160K *

Transform patient care by ensuring safe, effective medication management. Collaborate with interdisciplinary teams to enhance outcomes while overseeing pharmacy operations and supporting staff develop...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Drive impactful training and coaching for dental practices, enhancing adoption of digital workflows and intraoral scanning. Collaborate with clinicians and leaders to ensure operational readiness and...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $230K *

Join a team that's redefining SoC design by owning subsystem development, integrating third-party IP, and optimizing PPA for next-gen architectures. Contribute across all design stages and drive impac...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive sales performance by managing comprehensive compensation strategies that align with company goals. Collaborate across teams to design and implement effective plans, analyze data trends, and ensu...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Staffing

$100K - $500K+*

Join a dynamic team as you build trusted relationships, conduct in-home inspections, and provide tailored solutions for homeowners. Leverage industry-leading training and technology to drive your sale...

5 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Support financial analysis and reporting for global operations, collaborating with cross-functional teams to enhance insights and streamline processes across manufacturing networks in North America, E...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$174K - $255K *

Unlock your potential as a senior product leader driving digital growth strategies. Shape product vision and multi-year roadmaps to enhance customer engagement and revenue across diverse channels in a...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform biologics drug discovery by leading antibody engineering campaigns, optimizing therapeutic formats, and collaborating across teams to advance innovative solutions from concept to candidate n...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive revenue growth by managing key customer relationships and delivering accurate forecasts. Collaborate with teams to support product development and ensure compliance with industry standards while...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Pioneer engineering excellence by overseeing construction projects, ensuring compliance with standards, and managing documentation. Collaborate with teams to deliver high-quality infrastructure soluti...

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Shape the future of advanced RF systems integration and testing. Collaborate with experts to ensure seamless hardware and software functionality, leveraging cutting-edge tools and methodologies in a d...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$160K - $200K *

Innovate operational excellence in Clinical Operations by leading strategic initiatives, workforce planning, and cross-functional alignment to drive organizational effectiveness and support clinical d...

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$93K - $114K *

Engage with clients to unlock their potential through diverse therapeutic approaches. Enjoy flexible scheduling and competitive compensation while making a meaningful impact in the lives of individual...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $140K *

Reimagine financial strategy as you drive analytical rigor and strategic clarity in a high-impact role. Collaborate with cross-functional teams to support growth initiatives and shape the future of a...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.