Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$204K - $346K *

Transform patient care by leading a physician-centered team in a collaborative environment. Deliver value-based medicine with integrated behavioral health support, utilizing advanced technology for en...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Engage with key decision-makers to drive growth in mid-market accounts. Take ownership of the full sales cycle, leveraging your expertise to build a robust pipeline and shape the sales strategy in a d...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$130K - $155K *

Champion the design of high-performance AMS circuits for SerDes PHY, collaborating with cross-functional teams to define specifications and implement transistor-level designs, ensuring optimal power...

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's shaping the future of adhesive technology by leading innovative R&D projects, mentoring talents, and ensuring product compliance with industry standards in a dynamic and collaborati...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$206K - $252K *

Join a dynamic team to lead clinical pharmacology strategies for late-stage development, focusing on REM-422 and emerging pipeline programs. Collaborate cross-functionally to drive data-driven decisio...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in driving revenue and market share growth for the East region by developing strategic sales plans and managing a team of independent sales representatives to promote innovative roofin...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Optimize backend systems for a financial platform, integrating AI features and ensuring reliability across multiple regions. Collaborate with global teams to enhance product capabilities and maintain...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $223K *

Unlock potential by leading human-centered design efforts in clinical settings, translating user insights into AI-enabled solutions that enhance patient care and clinician efficiency within a collabor...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by managing complex liability claims and collaborating with diverse teams to drive effective risk management solutions. You'll play a key role in evaluating claims, coordinating li...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $150K *

Engage as a key Contract Manager, overseeing procurement agreements and providing strategic guidance across teams. Collaborate on complex projects, ensuring compliance and effective negotiation while...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $160K *

Lead critical evaluations of biological risks, mentor junior specialists, and ensure high-quality labeling for AI safety classifiers in a dynamic life-sciences environment focused on biodefense and bi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$160K - $229K *

Transform client experiences by leading SAP CX solutions, ensuring seamless integration and delivery from discovery to go-live while collaborating with cross-functional teams to drive business success...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$109K - $144K *

Join a dynamic team to drive operational excellence and process improvements in healthcare. Lead complex initiatives, influence strategy, and enhance care delivery while collaborating across multiple...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive analytical excellence by defining key business problems, extracting insights, and influencing strategic decisions across core business areas. Collaborate with teams to enhance metrics and outcom...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a team that's dedicated to solving complex problems through data-driven insights. You'll own the analytical function for key business areas, driving impactful decisions and outcomes in a fast-pac...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Engage, activate, and strengthen a diverse creator community by designing tailored strategies that enhance participation and relationships, ensuring the Creator Program remains a trusted resource for...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$133K - $173K *

Unlock potential by leading the commissioning of hyperscale data centers. Manage project lifecycles, coordinate teams, and ensure compliance with client requirements while fostering strong stakeholder...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$130K - $155K *

Lead the charge in optimizing AI serving infrastructure using vLLM and SGLang within a dynamic, autonomous team. Collaborate on deployment strategies, performance tuning, and GPU optimization to drive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$153K - $163K *

Unlock potential by providing expert technical intelligence support for NC3 programs, analyzing threats, and advising leadership to enhance operational effectiveness and sustainability in a critical d...

3 days ago

  •   15+ years exp.  •   Enterprise Technology

$123K - $135K *

Engage with existing customer accounts to drive renewal retention and expansion revenue. Collaborate with cross-functional teams to identify growth opportunities and ensure customer satisfaction while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $210K *

Champion innovative content strategies to transform editorial operations, enhance audience engagement, and establish a trusted resource for leaders in government and education. Drive organizational ch...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$133K - $200K *

Lead and elevate analytic approaches to support contract negotiations, drive strategic initiatives, and mentor a skilled team, enhancing provider relationships and regulatory compliance to improve the...

Massachusetts, USRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $95K *

Advance your career by driving new business growth through proactive outreach, building strong relationships, and consistently exceeding sales targets in a dynamic, remote environment focused on B2B s...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Manage client engagements end-to-end while mentoring associates and driving team success. Leverage technical expertise to resolve complex tax issues and enhance client service through collaboration an...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$250K - $300K *

Shape the future of AI-powered implementations by leading a dynamic team, redefining best practices, and building a robust partner ecosystem to enhance client success and drive growth in a fast-paced...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.