Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$75K - $90K *

Join our team to manage HR programs, enhance talent acquisition, and support employee development in a dynamic environment. Your expertise will drive strategic goals and foster a positive workplace cu...

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$210K - $230K *

Lead the charge in developing enterprise pricing strategies that optimize profitability and drive growth across diverse service sectors, ensuring alignment with market conditions and client needs whil...

RemoteRemote

3 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$102K - $204K *

Lead the charge in building corporate finance capabilities for a global orthopedics company. This role combines hands-on execution with strategic analysis, supporting capital structure, financing, and...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$109K - $174K *

Drive innovative research in immunology, focusing on immune cell roles in health and disease. Collaborate with cross-functional teams to design studies, analyze data, and contribute to therapeutic adv...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Partner with us to drive early-portfolio alliances in oncology, ensuring alignment with scientific objectives and corporate strategy. Collaborate across teams to manage partnerships, oversee project t...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by developing and optimizing machine learning models, collaborating with cross-functional teams to drive data-driven solutions and enhance predictive analytics in a dynamic, Agile...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$65K - $130K *

Engage in high-volume B2B sales, driving growth in energy procurement for SMBs. Utilize cold calling and relationship-building to optimize energy spend and deliver tailored solutions, while collaborat...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the charge in web growth design, optimizing top-of-funnel experiences to enhance customer engagement and conversion. Collaborate with cross-functional teams to create compelling, high-quality web...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $95K *

Take ownership of client-centric commerce media strategies, optimizing campaigns across platforms like Amazon and Walmart. Leverage data insights to drive growth and ensure client satisfaction while c...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Unlock potential by leading the full sales cycle, building executive relationships, and driving business transformation across industries. Collaborate with teams to innovate sales processes and ensure...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$315K - $370K *

Join a team that's redefining offensive security by leading engineering efforts to transform research into scalable, customer-facing products. Drive strategy, execution, and innovation across multiple...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Optimize sales operations by driving forecasting accuracy and commission strategies. Collaborate with leadership to enhance pipeline management and operational efficiency, ensuring scalable growth and...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Unlock potential by leading compliance initiatives and advising leadership on regulatory strategies. This role ensures adherence to laws, mentors staff, and collaborates with stakeholders to mitigate...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Drive high-throughput screening initiatives to evaluate siRNA efficacy in mammalian cells. Lead a team in developing automated processes and assays, collaborating across projects to enhance drug devel...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$106K - $197K *

Elevate your career by managing complex revenue accounting activities, leading process improvements, and collaborating across teams to enhance scalability and efficiency in a dynamic environment focus...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$122K - $204K *

Drive impactful reporting and analytics for utility operations, translating complex business needs into actionable insights. Collaborate with cross-functional teams to ensure data integrity and delive...

3 days ago

  •   Less than 5 years exp.  •   Business Services

$175K - $237K *

Lead the charge in digital manufacturing innovation, transforming operational needs into practical solutions. Collaborate globally to enhance data, AI, and automation capabilities, ensuring safe and e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$71K - $124K *

Unlock potential by driving revenue growth and customer retention across academic and healthcare institutions. Manage large accounts, develop strategic plans, and build trusted relationships to align...

Massachusetts, USRemote

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Empower a culture of safety and resilience by leading cross-functional EHS and Business Continuity initiatives across multiple North American operational sites, ensuring compliance, risk mitigation, a...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $195K *

Engage in strategic business development, overseeing global projects and teams. Drive long-term planning, policy formation, and customer negotiations while fostering collaboration with senior manageme...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$170K - $250K *

Join a dynamic team as you drive product adoption and build relationships within the eye care community. Leverage insights and collaborate cross-functionally to enhance customer engagement and optimiz...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $180K *

Join us in leading product strategy and execution for a diverse portfolio, enhancing Provider Contracting and Credentialing. Collaborate with cross-functional teams to drive innovation, improve custom...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $97K *

Take ownership of regulatory proceedings by coordinating filings and managing deadlines. Collaborate with cross-functional teams to ensure timely submissions and maintain accurate records, enhancing t...

3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$153K - $290K *

Transform drug discovery by leading a dynamic team in medicinal chemistry, driving innovative small-molecule candidates from concept to IND-ready status while fostering collaboration across a global n...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$177K - $338K *

Champion DMPK project leadership by ensuring high-quality data delivery and supporting drug candidate progression through innovative modeling and cross-functional collaboration in a dynamic biotech en...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.