Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$127K - $236K *

Elevate your career by leading a dynamic AI team to innovate and implement cutting-edge solutions that enhance business processes and drive strategic insights across the organization. Join us in shapi...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$156K - $227K *

Elevate executive compensation strategies by designing and leading Total Rewards programs that align with organizational goals, while collaborating with key stakeholders to ensure compliance and effec...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $160K *

Unlock potential by leading complex cyber investigations, mentoring junior analysts, and analyzing sophisticated threats to safeguard AI systems from misuse. Drive impactful decisions and enhance safe...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $167K *

Transform the future of technology solutions by developing full-stack applications that enhance data accessibility and user experience. Collaborate with cross-functional teams to deliver secure, scala...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$144K - $211K *

Drive engineering excellence by leading a high-performing team in implementing and scaling industrial control systems. Collaborate across functions to ensure reliable, maintainable solutions that supp...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $160K *

Engineer the future of critical facility commissioning by leading project teams, managing schedules, and ensuring compliance with design and safety standards. Drive successful project execution throug...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$130K - $160K *

Unlock your potential as you learn product management directly from a CEO. Gain hands-on experience across functions in a fast-growing tech startup, preparing for a future leadership role in product o...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $229K *

Lead the design and development of AI-driven solutions within SAP S/4HANA, integrating advanced AI technologies to drive business transformation and innovation across enterprise environments. Mentor t...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by providing strategic leadership in student funding administration, ensuring compliance and efficiency in managing tuition, stipends, and fellowships for graduate programs while coll...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Champion data-driven decision-making by analyzing key metrics and driving impactful outcomes across growth, product, AI, and partnerships. Collaborate with teams to define problems, extract insights...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$123K - $135K *

Engage with existing customer accounts to drive renewal retention and expansion revenue. This growth-focused role emphasizes consultative upselling and cross-selling, ensuring customer satisfaction wh...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $141K *

Join a team that's dedicated to providing expert bioinformatics support, bridging customer needs with innovative NGS solutions. You'll play a key role in pre- and post-sales activities, ensuring custo...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $92K *

Join a team that's advancing gene editing through hands-on oligonucleotide synthesis, purification, and conjugation. Collaborate with senior scientists to deliver high-quality materials for in vitro a...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $92K *

Engineer innovative oligonucleotide synthesis and purification processes, collaborating with senior scientists to deliver high-quality materials for gene editing and targeted delivery programs in a dy...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Lead water infrastructure strategies, ensuring efficient design and compliance across data center projects. Collaborate with teams to secure agreements and manage risks, enhancing sustainability and c...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Empower our engineering teams by leading technical recruitment efforts. Dive deep into candidate sourcing, build strong pipelines, and enhance the hiring process while ensuring a positive candidate ex...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Transform program execution by coordinating large-scale data center initiatives, ensuring alignment across stakeholders, managing risks, and driving milestones to successful completion while fostering...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$90K - $130K *

Join a team that's driving large-scale infrastructure projects. As a Project Manager, you'll lead initiatives from kickoff to closeout, ensuring alignment with program objectives and stakeholder expec...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$85K - $100K *

Oversee and enhance special education programs by supervising staff, ensuring compliance with regulations, and facilitating effective collaboration among educators and families to support student succ...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$77K - $123K *

Unlock your potential by fostering client relationships and advising on benefit plans. Collaborate with carriers and clients to enhance service delivery, ensuring compliance and strategic solutions th...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $117K *

Elevate your career by leading SDTM programming activities, ensuring quality deliverables, and collaborating cross-functionally to optimize clinical data transformation in a dynamic environment...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$128K - $250K *

Innovate enterprise sales by leading the strategy for large deal pursuits, engaging C-suite clients, and delivering transformative solutions in retail and logistics sectors...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $222K *

Lead the charge in financial planning and analysis for Brokerage, driving insights and governance. Collaborate with leadership to enhance performance, manage budgets, and develop high-performing teams...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $145K *

Lead campaign strategy and execution for oncology pharma marketing, driving performance optimization and cross-functional collaboration. Own end-to-end campaign management, ensuring alignment with bus...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $110K *

Lead the charge in fostering brand loyalty and enhancing customer experiences while supporting the Store Manager in achieving sales objectives and maintaining high standards of service and team develo...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.