Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $125,890
$167K - $190K *
Lead impactful genomic studies in Oncology, interpreting NGS data to drive biological insights and propose novel experiments. Collaborate with cross-functional teams to develop innovative drug strateg...
Reposted 3 days ago
Associate Medical Director- Rare Neuro
$175K - $200K *
Drive strategic medical initiatives in Rare Neurology, collaborating with cross-functional teams to enhance patient outcomes. Leverage your expertise to shape launch strategies and foster relationship...
Reposted 3 days ago
Senior Manager, Regulatory Affairs, Advertising and Promotion
$150K - $170K *
Join us to lead regulatory review of promotional materials, ensuring compliance with FDA regulations. Collaborate with cross-functional teams to enhance product messaging and contribute to the success...
Reposted 3 days ago
Equity Sales Trading, Executive Director
$160K - $200K *
Empower your career by bridging clients and the equity market through precise execution and strategic relationship building. Innovate and drive revenue growth while ensuring compliance and operational...
Reposted 3 days ago
VP, Global Sales, Inventory & Operations Planning
$175K - $210K *
Lead the global SIOP process, ensuring synchronization across Sales, Marketing, and Supply Chain functions to optimize inventory and enhance operational efficiency for $1.2B in annual sales. Drive str...
Reposted 3 days ago
Psychiatric Nurse Practitioner (PMHNP)
$200K - $257K *
Unlock potential by providing compassionate psychiatric care in a hybrid setting. Collaborate with a dedicated team to enhance patient outcomes while enjoying flexible scheduling and a supportive work...
3 days ago
$86K - $95K *
Transform your career by joining a dynamic team focused on quality control. Contribute to testing and analysis in a cGMP environment, ensuring compliance and excellence in pharmaceutical products. You...
Reposted 3 days ago
Director and Associate General Counsel, Commercial Operations
$160K - $190K *
Join our dynamic legal team to support commercial operations and transactions. You'll manage contracts, advise on compliance, and enhance processes in a fast-paced environment, driving legal support a...
Reposted 3 days ago
Marketing Manager, Employer Branding & Talent Marketing
$110K - $130K *
Champion our employer brand initiatives by leading integrated marketing campaigns, optimizing recruitment strategies, and enhancing candidate engagement to position us as a top choice for talent in th...
Reposted 3 days ago
$140K - $175K *
Shape technical innovation by leading cross-team efforts in system architecture and development. Drive scalable improvements, mentor peers, and influence business outcomes while ensuring long-term mai...
3 days ago
$110K - $130K *
Optimize product costs and drive cost engineering processes for electromechanical systems. Collaborate with finance and engineering teams to establish best practices and support data-driven decisions...
Reposted 3 days ago
$300K - $500K *
Champion innovation by architecting and developing high-performance, real-time trading web apps. Leverage your expertise to enhance user experience and drive product evolution in a dynamic, collaborat...
3 days ago
$64K - $102K *
Elevate network performance by deploying and optimizing voice solutions, ensuring 99.999% uptime. Collaborate on network planning and security, while providing expert support and documentation for com...
Reposted 3 days ago
$80K - $95K *
Elevate your nursing career by leading a dedicated team, delivering exceptional resident care, and implementing personalized care plans in a collaborative, supportive environment committed to quality...
Reposted 3 days ago
Staff Product Manager, Agentic Quoting Tools
$180K - $207K *
Optimize the request-to-quote experience for key customers by redesigning workflows, integrating AI agents, and enhancing operational efficiency. Collaborate across teams to drive product strategy and...
3 days ago
$60K - $120K *
Empower growth by engaging existing customers, identifying upgrade opportunities, and managing the full sales cycle. Build trust with small business owners while driving revenue through effective outr...
3 days ago
Staff, Product Manager - Identity
$155K - $228K *
Join a team that's shaping the future of identity products, delivering secure, developer-first experiences. Collaborate with leadership to build innovative solutions that empower customers and enhance...
3 days ago
Account Executive - North America New Logo
$140K - $220K *
Join a dynamic team focused on driving new business growth through strategic sales initiatives. Engage with key decision-makers, execute impactful presentations, and leverage multi-channel outreach to...
3 days ago
Clinical Sales Specialist, MCS - Northeast
$120K - $145K *
Transform the clinical sales landscape by promoting MCS products, driving revenue, and providing essential training and support to medical professionals while ensuring exceptional customer experiences...
Reposted 3 days ago
Regulatory Affairs Director (Remote - United States)
$211K - $290K *
Champion global regulatory strategies to drive product approvals and market access for innovative dental solutions. Collaborate with cross-functional teams to navigate complex regulatory landscapes an...
3 days ago
INGENYX - Regulatory Affairs Specialist
$87K - $109K *
Optimize global regulatory activities for medical devices, ensuring compliance in labeling, UDI, and product data. Collaborate with cross-functional teams to support product registrations and maintain...
Reposted 3 days ago
Regional Sales Director, NW & Rockies
$125K - $150K *
Drive innovation in medical device sales by leading regional growth initiatives, expanding partnerships, and enhancing market presence while directly connecting with healthcare professionals in the NW...
Reposted 3 days ago
Senior Mechanical Engineer (Teradyne, North Reading, MA)
$121K - $194K *
Join a dynamic team as you design electro-mechanical solutions for advanced aerospace and defense applications, collaborating across functions to translate customer needs into manufacturable designs a...
Reposted 3 days ago
Affiliate Marketing Manager - US, Remote
$85K - $144K *
Take ownership of the North America affiliate channel by driving strategy, measuring performance, and fostering growth while leading a team and optimizing partnerships for maximum profitability...
Reposted 3 days ago
$130K - $155K *
Drive operational excellence by managing TechOps and enhancing IT infrastructure. Collaborate with DevOps and SecOps to ensure high availability and security of applications while mentoring a high-per...
3 days ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.