Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,888

Sort By: Relevance

$110K - $130K *

Unlock potential by leading complex commercial real estate due diligence projects. Collaborate with multidisciplinary teams to provide technical guidance and client leadership, ensuring high-quality d...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$180K - $220K *

Champion quality excellence by leading strategic Quality Assurance operations, ensuring compliance and operational effectiveness across commercial and clinical manufacturing, while driving organizatio...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$68K - $109K *

Join a team that's dedicated to developing cutting-edge semiconductor test systems. As a Mechanical Engineer I, you'll collaborate with experts to design, prototype, and enhance innovative electromech...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive the web strategy and optimization for multiple domains, enhancing user engagement and conversion rates. Lead a dynamic team to implement data-driven improvements and ensure a cohesive online pre...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Elevate HR operations by managing and optimizing HRIS systems, ensuring data integrity, and collaborating across departments to enhance efficiency and support strategic decision-making in a dynamic en...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$177K - $278K *

Optimize global alliance management by leading partnerships, driving governance, and enhancing best practices. Collaborate with cross-functional teams to achieve strategic objectives and ensure compli...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$187K - $327K *

Empower your career by leading evaluations of innovative drug opportunities. Collaborate cross-functionally to drive strategic partnerships and enhance patient outcomes in a dynamic life sciences envi...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$162K - $203K *

Join a team that's transforming digital tinnitus care in the U.S. by leading commercial execution across healthcare sectors. Drive adoption and optimize partnerships to enhance patient engagement and...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$113K - $141K *

Manage elevator modernization projects, leading field technicians to ensure safety, quality, and budget adherence while fostering collaboration across teams and maintaining strong customer relationshi...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$98K - $135K *

Grow your career with a key role ensuring supplier quality within manufacturing, focusing on product development, non-conformance management, and supplier audits to maintain high standards in a dynami...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Drive growth by leading sales and technical initiatives in heating and combustion solutions across the Southeast Region, fostering relationships with key clients and internal teams to achieve strategi...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$186K - $218K *

Architect robust security solutions to safeguard corporate infrastructure and user devices. Collaborate with IT and engineering teams to identify risks and implement effective security measures, ensur...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $240K *

Transform AI from concept to production by building and deploying solutions in manufacturing and supply chain. Lead a team to ensure adoption and drive business outcomes through hands-on engineering a...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $185K *

Accelerate your career by executing regional payor strategies to secure coverage and reimbursement for innovative Surgical Glaucoma products. Collaborate with cross-functional teams and build relation...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$65K - $175K *

Grow your career with us by designing innovative software solutions for unmanned systems. Collaborate with cross-functional teams to enhance mission management tools and tackle complex autonomy challe...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $185K *

Reimagine the customer acquisition journey by leading data-driven digital strategies that optimize funnels, elevate conversion rates, and enhance profitability across product lines in a rapidly evolvi...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to optimizing Salesforce for enhanced performance and automation. You'll manage daily administration, collaborate on complex builds, and drive AI integration, ensuring a s...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Transform patient care by working as an Associate Optometrist, providing full-scope optometric services with professional autonomy in a supportive environment, and enjoying flexible scheduling options...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$97K - $131K *

Transform wireless communication systems by solving intricate RF challenges, collaborating with global teams, and mentoring engineers while managing impactful projects for leading clients...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$163K - $203K *

Elevate security standards by leading classified design and accreditation for defense facilities. Collaborate with cross-functional teams to ensure compliance and streamline processes for rapid deploy...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$130K - $160K *

Oversee complex commercial construction projects from preconstruction to closeout, ensuring financial performance, scheduling, and client satisfaction while managing multiple projects concurrently and...

3 days ago

  •   5 - 7 years exp.  •   Media

$90K - $95K *

Join a team that's driving brand visibility and growth in the on-premise channel. As an On-Premise Specialist, you'll manage key accounts, optimize sales strategies, and collaborate with distributors...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Reimagine operational excellence by integrating data intelligence and insights across multiple business functions. This role enhances strategic decision-making, optimizes workflows, and supports marke...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $100K *

Elevate operational excellence by leading continuous improvement initiatives. Collaborate with cross-functional teams to implement Lean and Six Sigma methodologies, enhancing quality, efficiency, and...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$66K - $100K *

Elevate your career by troubleshooting and optimizing CNC lathe operations. Collaborate with a skilled team to set up, review programs, and ensure precision in aerospace manufacturing. Drive quality a...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.