Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$155K - $213K *

Lead the charge in designing and advancing enterprise-scale Test Data Management solutions, ensuring secure and compliant use of test data across diverse technology landscapes while collaborating with...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$138K - $191K *

Join a team that's redefining healthcare innovation by translating ideas into impactful solutions. Collaborate with senior executives to drive strategic initiatives and enhance population health throu...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$129K - $177K *

Drive the future of AI integration by designing and delivering agentic workflows that enhance user experiences. Lead a team while actively contributing to production code, ensuring reliable AI systems...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Shape the future of enterprise data capabilities by leading product strategy and agile teams to enhance personalized decision-making across channels. Collaborate with stakeholders to translate busines...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Shape the future of healthcare by leading the Organic Risk Adjustment program. Drive strategic initiatives, foster collaboration across teams, and implement innovative solutions to enhance performance...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$129K - $177K *

Champion the development of intelligent decision systems using machine learning and reinforcement learning to enhance personalized healthcare recommendations, driving impactful outcomes for millions o...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Shape the future of Medicaid wellness by leading innovative strategies and solutions that enhance health outcomes for underserved populations. Collaborate with diverse teams to develop impactful progr...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Join us to shape the future of member experiences in healthcare by leading innovative design projects, collaborating with cross-functional teams, and enhancing service delivery through user-centered d...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$126K - $173K *

Develop and enhance a data-driven decisioning platform, collaborating with cross-functional teams to optimize personalized member experiences while balancing immediate needs with long-term strategic g...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$138K - $191K *

Shape the future of legal operations by managing complex investigations and litigation. Provide expert legal counsel, mitigate risk, and partner with stakeholders to communicate complex issues effecti...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$138K - $190K *

Transform enterprise Test Data Management by leading product vision, strategy, and delivery. Collaborate with stakeholders to ensure secure, compliant, and innovative test data solutions that enhance...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Empower healthcare transformation by developing strategic initiatives that enhance operational efficiency and clinician productivity. Collaborate cross-functionally to drive impactful solutions and im...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$71K - $97K *

Unlock your potential as a Senior Workforce Management Professional, blending strategic analysis with operational execution to enhance staffing and service delivery in a dynamic environment. Drive imp...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing and executing business strategies to acquire new clients, expand market reach, and drive sustainable revenue growth through consultative selling and strategic relationshi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$115K - $182K *

Join a team that's shaping the future of ultrasound imaging by integrating hardware and software to create innovative, safe, and scalable solutions that enhance clinical performance and patient care a...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $151K *

Unlock potential by providing expert remote clinical applications support for advanced molecular imaging. Leverage your clinical knowledge and customer service skills to enhance productivity and deliv...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $182K *

Elevate the future of ultrasound imaging by leading system architecture, aligning technology strategy with clinical and business objectives, and mentoring engineering talent to drive innovation and ex...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Reimagine your career by joining a dynamic team focused on optimizing Artificial Lift systems. You'll lead technical installations, enhance well productivity, and ensure adherence to safety standards...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$81K - $165K *

Unlock potential by managing the financial integrity of a high-impact loyalty program. Ensure compliance, accuracy, and timely reporting while collaborating with cross-functional teams to drive growth...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$337K - $437K *

Join a team that's dedicated to providing comprehensive hematology and oncology care. Collaborate with a multidisciplinary team, engage in patient-centered practices, and contribute to medical educati...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$225K - $240K *

Transform business growth by leading a high-performing sales team, driving strategic initiatives, and enhancing client relationships to accelerate revenue across digital solutions in North America...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $100K *

Champion influencer marketing strategies that drive brand growth, manage client relationships, and execute impactful campaigns. Collaborate cross-functionally to analyze performance and innovate appro...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$150K - $160K *

Drive financial excellence by leading analysis and insights for sales, margin, and inventory performance. Collaborate with cross-functional teams to enhance decision-making and optimize business strat...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Join a team that's dedicated to advancing affordable housing investments by identifying and evaluating LIHTC opportunities, preparing investment proposals, and supporting nationwide origination effort...

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.