Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$131K - $190K *

Empower innovation by leading cell biology research for cutting-edge biopharma technologies. Collaborate with a multidisciplinary team to develop and validate novel cell-based assays and platforms tha...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$87K - $119K *

Drive innovative solutions in aerospace and defense by collaborating with cross-functional teams to enhance ultra-wideband transceiver products, ensuring customer satisfaction and successful design in...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $140K *

Unlock potential by leading the design and governance of structured exam content. Drive standards compliance and metadata alignment across assessment systems, ensuring seamless integration and functio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $130K *

Drive community engagement by managing digital resources and support for educators. Oversee outreach programs, content channels, and strategic growth initiatives to enhance user experience and foster...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$142K - $213K *

Join a team dedicated to advancing neuroimmunology research and clinical trials. Collaborate cross-functionally to ensure strong data analysis, oversight, and documentation while contributing to innov...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$138K - $207K *

Lead the design and execution of RTSM systems for global clinical trials, ensuring timely delivery and compliance. Collaborate with cross-functional teams to enhance quality and efficiency, safeguardi...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$189K - $283K *

Shape the future of clinical operations by leading strategic planning and execution for a global team. Drive performance, enhance productivity, and ensure effective delivery of clinical studies across...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$181K - $272K *

Shape the future of data science in cardiovascular, renal, and metabolism research by leading operational strategies, optimizing AI capabilities, and fostering cross-functional collaboration to drive...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $195K *

Transform client service delivery by leading the IP US Patent team, enhancing efficiency, managing workflows, and driving quality control. Collaborate with practitioners to ensure exceptional support...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$145K - $210K *

Lead the development and integration of associates in a dynamic legal environment. Collaborate with practice leaders to optimize staffing, enhance professional growth, and ensure equitable workload di...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$135K - $176K *

Lead the charge in providing expert paralegal support for fund formation, managing organizational documents, compliance, and due diligence while collaborating with attorneys in a dynamic, fast-paced e...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$192K - $225K *

Champion global security and resilience initiatives, ensuring safety and compliance across operations. Lead strategic programs in crisis management, insider risk, and business continuity while fosteri...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Technical Services

$165K - $190K *

Champion client engagement and project management while leading ERP implementations in higher education and public sectors. Drive financial optimization and mentor teams to deliver impactful solutions...

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Today

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Shape the future of financial strategy by overseeing capital budgeting and investment analysis. Collaborate with leadership to ensure compliance and optimize financial performance across major project...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $170K *

Join a team that's driving growth in government sales by leading strategic initiatives with the FAA. This role focuses on expanding business opportunities and fostering relationships across complex av...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $275K *

Lead strategic business development efforts, fostering relationships with government agencies and partners to drive R&D initiatives and align with GE Aerospace's technology roadmap. Manage opportuniti...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$73K - $183K *

Reimagine client solutions by delivering high-quality development and analysis. Collaborate with teams to meet client satisfaction objectives while managing complex projects and ensuring technical qua...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$216K - $305K *

Engage in providing comprehensive psychiatric care for geriatric patients, collaborating with multidisciplinary teams to enhance treatment outcomes. Participate in education and training while ensurin...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Accelerate progress at the forefront of cybersecurity by leading threat hunting initiatives. Engage with clients to deliver tailored IT solutions, analyze complex data, and enhance security measures i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $105K *

Unlock your potential by leading branch operations, driving strategic initiatives, and enhancing team performance. Collaborate with stakeholders to achieve financial goals while fostering a culture of...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$197K - $225K *

Contribute to cutting-edge AI transformations by designing and deploying ML models. Collaborate with cross-functional teams to solve complex business challenges and optimize data pipelines in a fast-p...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $180K *

Transform the user experience by leading innovative product strategies for a tech-driven learning platform. Drive AI initiatives, collaborate with cross-functional teams, and mentor product managers t...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$180K - $210K *

Elevate your career by joining a dynamic team focused on quantitative research and investment analysis. Collaborate with experts to leverage data science and statistical models, driving insights that...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $110K *

Inspire excellence as an Executive Assistant, supporting our Infrastructure and Real Assets Investment Team with administrative tasks, client updates, and project coordination in a hybrid work environ...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Transform power generation strategies by leading innovative solutions and optimizing energy contracts. Drive collaboration across teams to enhance project management and accelerate market readiness fo...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.