Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,012

Sort By: Relevance

$95K - $250K *

Join a dynamic team to drive energy efficiency solutions, engaging homeowners through consultative sales and hands-on assessments. Enjoy a lucrative career path with no cold calling and comprehensive...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $145K *

Engage in transformative financial leadership, overseeing accounting, reporting, and compliance. Your expertise will drive operational efficiency in a mission-critical environment, impacting national...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$268K - $282K *

Shape the future of media products by driving strategy and innovation. Collaborate with cross-functional teams to enhance measurement and optimization capabilities, ensuring impactful solutions for cl...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K *

Drive the development of a cutting-edge platform, enhancing integrations and architecture for payroll and HR systems. Collaborate closely with a small team to ensure a successful launch and ongoing im...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$175K - $200K *

Transform our marketplace marketing strategy to drive demand and growth. Lead a team to enhance buyer engagement and supplier acquisition, ensuring alignment across functions while optimizing programs...

3 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$130K - $155K *

Join us to lead security and compliance initiatives within a dynamic platform team. You'll leverage your expertise to enhance production infrastructure, ensuring robust protection and reliability for...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Drive your career forward by enhancing security systems that protect our workforce and cloud services. Own identity controls, endpoint security, and incident response while building automation for sca...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$133K - $156K *

Drive development and delivery of data products, engage stakeholders, and translate business needs into solutions. Lead cross-functional teams to enhance reporting and analytics, while ensuring data g...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Empower business growth by building strategic relationships and originating multifamily loans. Utilize your expertise to manage the loan process, advise clients, and enhance community presence in the...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$99K - $232K *

Lead the charge in transforming banking platforms through innovative test execution, ensuring quality and performance of software solutions by managing teams and driving strategic testing initiatives...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$99K - $232K *

Join a team that's transforming core banking platforms by optimizing operational efficiency, implementing innovative software solutions, and inspiring your team to deliver exceptional consulting servi...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$240K - $280K *

Elevate regional medical value strategies by engaging with key stakeholders, translating complex evidence into actionable insights, and leading cross-functional initiatives to enhance patient access a...

Bedford, MARemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$240K - $280K *

Elevate your career by leading regional medical value strategies, engaging with key healthcare stakeholders, and driving evidence-based decision-making to enhance patient access and formulary evaluati...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead cross-functional teams to drive enterprise modernization through AI solutions. Oversee complex implementations, ensuring alignment across technical and business stakeholders while delivering meas...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Champion the design and configuration of Ellucian Colleague Financial Aid systems, ensuring alignment with client strategies while providing expert technical support and training to enhance operationa...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$240K - $360K *

Drive clinical innovation by leading multidisciplinary teams in trial strategy, design, and execution. Oversee safety monitoring and contribute to regulatory submissions, ensuring high-quality outcome...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$103K - $171K *

Lead the charge in overseeing accounting operations, ensuring compliance and accuracy in financial reporting. Manage a team, drive month-end close activities, and support audits while fostering a coll...

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $200K *

Lead the transformation of military air operations by integrating commercial airline practices into modern command and control software. Collaborate with cross-functional teams to enhance operational...

3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$112K - $168K *

Lead the charge in managing inbound lead processes and executing targeted outbound prospecting. Oversee demand progression from qualification to sales handoff, ensuring effective engagement and conver...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$179K - $295K *

Empower partners by providing senior technical strategy in Risk and Security. Collaborate on innovative solutions, drive AI adoption, and enhance partner capabilities through workshops and training, e...

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Elevate your career by leading revenue and expense management strategies across a multifamily portfolio. Drive data-driven decision-making, optimize financial performance, and mentor a team of analyst...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$450K - $500K+*

Elevate the life sciences sector by leading a team that drives AI adoption in pharma and biotech. You'll coach sales executives, refine strategies, and build trusted relationships to transform drug de...

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in designing a cutting-edge platform for modern data centers, integrating AI and cloud technologies. Collaborate with cross-functional teams to build a robust, scalable architecture th...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$200K - $290K *

Contribute to the advancement of cancer therapies by managing analytical development and quality control operations, ensuring compliance with regulatory standards, and collaborating across teams to en...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$72K - $89K *

Join a dynamic Early Intervention team to deliver impactful OT services for children (birth-3 years) with developmental delays. Collaborate with families and professionals to foster growth in natural...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.