Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$92K - $166K *

Lead complex, customer-driven projects from initiation to delivery, ensuring accountability for scope, schedule, and resources. Collaborate across functions to drive strategic planning and deliver act...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Join a team that's redefining product management by leading AI and automation initiatives. Drive strategic roadmaps, enhance operational efficiency, and deliver impactful solutions while collaborating...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's driving innovation in sheet metal manufacturing. Collaborate with cross-functional experts to optimize designs, manage supplier relationships, and ensure quality throughout the prod...

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $250K *

Transform your career in a high-income sales role with no cold calling. Engage homeowners, conduct energy assessments, and recommend efficiency upgrades in a booming industry with significant earning...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$182K - $226K *

Unlock potential by joining a dynamic team that drives customer success through technical expertise and innovative solutions, enhancing product engagement and collaboration in a fast-paced startup env...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $110K *

Optimize manufacturing processes while ensuring quality, compliance, and efficiency. Collaborate across teams to support low-volume, high-mix defense manufacturing, enhancing production performance an...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$90K - $120K *

Engage in leading strategic client relationships while guiding a team of campaign executives. Champion innovative marketing campaigns and optimize account profitability to drive success and deliver ex...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$77K - $83K *

Unlock potential by leading the production of Active Pharmaceutical Ingredients while ensuring compliance with FDA and cGMP standards. Collaborate with teams to maintain safety, quality, and operation...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Drive a unified technical organization to enhance customer support from application discovery to project conversion, focusing on team development, technical selling, and improving customer experiences...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$162K - $208K *

Join a dynamic team providing essential optometry services to residents in nursing and assisted living facilities. Enjoy flexible scheduling, competitive compensation, and full administrative support...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $199K *

Join a dynamic team to lead automation projects in life sciences, enhancing operational efficiency and client engagement. Leverage your expertise to drive innovation and mentor others while ensuring c...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $199K *

Lead the charge in transforming life sciences through innovative automation solutions. Collaborate with cross-functional teams to enhance project delivery, client engagement, and operational efficienc...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $199K *

Shape the future of automation in life sciences by leading projects, mentoring teams, and driving innovation. Collaborate with clients to enhance operational efficiency and ensure compliance while fos...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $199K *

Deliver impactful automation solutions in life sciences by leading projects, mentoring teams, and enhancing client relationships. Drive operational efficiency and continuous improvement while ensuring...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $172K *

Transform healthcare delivery by managing CDI operations, liaising with vendors, ensuring quality, and fostering staff development. Join a collaborative team to enhance patient care through innovative...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in enhancing software quality by designing and executing automation tests. Collaborate with cross-functional teams to ensure robust performance and scalability of our digital platform...

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Shape the future of People Operations by driving innovative HR solutions, enhancing employee experiences, and managing key programs. Collaborate across teams to streamline processes and foster a posit...

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in offensive security research, tackling software supply chain vulnerabilities and zero-day threats. Collaborate with teams to innovate security capabilities and publish impactful find...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$173K - $209K *

Transform your career by leading biostatistical strategies for clinical trials, driving innovative therapies from design to regulatory submission. Collaborate with multidisciplinary teams to ensure da...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$212K - $333K *

Lead strategic initiatives in DMPK&M for the GI2 therapeutic area, overseeing a team to optimize drug development and ensure alignment with global research goals. Drive collaboration across functions...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$85K - $97K *

Transform the visual storytelling of journalism by designing engaging layouts and features across print and digital platforms. Collaborate with diverse teams to elevate narratives and innovate visual...

3 days ago

  •   Less than 5 years exp.  •   Media

$100K - $110K *

Accelerate progress at diverse construction projects by leading teams, managing scopes, and ensuring timely delivery while fostering strong client relationships and maintaining high standards of quali...

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$233K - $330K *

Elevate your career by leading innovative pricing strategies for cutting-edge AI solutions. Collaborate across teams to optimize monetization models and drive value in a dynamic market, ensuring Cisco...

RemoteRemote

3 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$112K - $118K *

Advance therapeutic innovations by designing and executing experiments to enhance RNA editing molecules, contributing to drug candidate characterization and collaboration efforts in a dynamic research...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.