Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$168K - $268K *

Join a team that's shaping legal strategies for business units, providing expert advice on contracts, compliance, and regulatory matters. Collaborate with multidisciplinary teams to align legal soluti...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $174K *

Join a dynamic team to support sales activities and enhance customer relations in the clinical setting. Drive product penetration and collaborate with internal teams to achieve business objectives and...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $163K *

Support audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance audit readiness and internal controls, ensuring effective communicatio...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$77K - $129K *

Unlock your potential as a Business Analyst, driving Agile software development efforts for diverse health industry projects, collaborating closely with stakeholders to deliver high-quality, scalable...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$74K - $124K *

Lead audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance internal controls and audit readiness, ensuring successful outcomes for f...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$85K - $141K *

Analyze loan files to ensure compliance with SBA requirements, identifying risks and deficiencies. Collaborate with lenders to clarify documentation and prepare detailed reports, maintaining high stan...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$113K - $188K *

Transform client operations by delivering innovative solutions using Microsoft Power Platform. Lead implementations, automate processes, and ensure high-quality development while collaborating with st...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$98K - $163K *

Analyze and support federal clients in oversight and monitoring of grant programs, ensuring program integrity and accountability. Collaborate with stakeholders to assess risks, develop recommendations...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$206K - $343K *

Transform your career by leading AI & Data initiatives for Energy Providers. Drive growth, build client relationships, and develop a high-performing team while delivering innovative solutions that add...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$113K - $188K *

Champion adolescent health initiatives by providing strategic guidance and support to federal agencies, enhancing youth engagement, and implementing evidence-based programs to improve outcomes for ado...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$113K - $188K *

Optimize security administration and reporting processes while collaborating with cross-functional teams to enhance data insights and compliance metrics. Drive effective use of Workday tools and ensur...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$102K - $170K *

Lead the charge in human-centered research, guiding projects from planning to analysis. Utilize primary research methods to enhance client programs and customer experiences, while managing multiple en...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$206K - $343K *

Lead the charge in transforming healthcare operations by delivering innovative performance solutions. Drive profitable growth through strategic program management and client engagement, ensuring measu...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$98K - $163K *

Transform early childhood initiatives by supporting federal programs through analysis, stakeholder engagement, and project management. Collaborate with diverse teams to enhance outcomes for children a...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$130K - $216K *

Lead complex healthcare data initiatives by managing teams, translating business needs into technical solutions, and ensuring data quality and integration. Collaborate with stakeholders to drive analy...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$107K - $178K *

Join a team that's driving innovation in life sciences consulting. Collaborate with clients to deliver impactful solutions in product planning, commercialization, and compliance while mentoring junior...

3 days ago

  •   Less than 5 years exp.  •   Business Services

$65K - $108K *

Champion the development and delivery of training materials and documentation, collaborating with stakeholders to ensure clarity and usability. Play a crucial role in enhancing learning and adoption t...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$102K - $170K *

Elevate your career by driving operational improvements in healthcare. Collaborate with clients to enhance performance through data analysis and strategic workflow redesign, ensuring impactful outcome...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Innovate within a dynamic team, driving impactful projects and solutions that enhance operational efficiency and foster growth across multiple departments. Your expertise will shape strategic initiati...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$123K - $157K *

Engage in comprehensive women's health care as a Certified Nurse Midwife, providing prenatal, postpartum, and gynecological services. Collaborate with a dedicated physician team while participating in...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$214K - $358K *

Optimize operations at the forefront of Oncology Medical Affairs, driving strategic initiatives, resource management, and cross-functional collaboration to enhance patient outcomes and organizational...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $250K *

Unlock potential as a vital leader in enhancing patient care. Drive growth through strategic engagement with healthcare professionals, ensuring effective use of product portfolios, while providing key...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$214K - $358K *

Elevate commercial strategy by leading global obesity portfolio development, integrating cross-functional teams, and driving impactful decisions to ensure strategic coherence and executional readiness...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$123K - $216K *

Drive client success by managing and growing a diverse portfolio of insurance clients. Leverage expertise in asset servicing and relationship management to deliver tailored solutions and enhance profi...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$171K - $300K *

Lead the control program for a regional business unit, ensuring effective governance and risk management. Collaborate with senior executives to enhance operational efficiency and drive strategic initi...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.