Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$176K - $243K *

Unlock potential by leading strategic initiatives in cardiovascular imaging, driving adoption of advanced technologies, and fostering partnerships to enhance patient care and clinical outcomes across...

RemoteRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Healthcare

$151K - $207K *

Unlock potential by driving strategic growth in healthcare sales, fostering executive relationships, and leading cross-functional teams to achieve commercial targets across Siemens Healthineers' Imagi...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$123K - $169K *

Lead the charge in driving strategic initiatives that enhance talent aggregation and curation, fostering profitable growth and expanding market share through innovative operational solutions...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $224K *

Transform healthcare operations by leveraging your expertise to drive efficiency and improve outcomes. Engage with clients to analyze needs, manage projects, and lead teams in delivering sustainable p...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $148K *

Elevate your career by driving pricing compliance and digitalization initiatives. Collaborate with cross-functional teams to analyze proposals, ensure adherence to financial guidelines, and enhance pr...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in data center innovation, managing critical systems and projects. Collaborate with diverse teams to ensure operational excellence and compliance, while driving technical advancements...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $140K *

Unlock the potential of facilities management by overseeing daily operations, budgets, and vendor relationships. Drive efficiency and customer satisfaction while leading a diverse team to enhance prop...

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$148K - $223K *

Drive the transition of our systems from startup to enterprise scale, ensuring reliability and performance. Collaborate with engineers to enhance infrastructure and lead production excellence in a fas...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$77K - $189K *

Empower growth by developing strategic relationships with Marketing and Ecommerce leaders, driving account expansion and cross-sell opportunities within a high-impact digital portfolio, while collabor...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$123K - $247K *

Partner with us to drive growth and innovation in digital sales, expanding our footprint within enterprise accounts. Collaborate with marketing and ecommerce leaders to deliver tailored solutions and...

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$148K - $223K *

Unlock potential by leading the transition from startup to enterprise-scale systems. Collaborate with engineers to enhance reliability, optimize performance, and automate infrastructure, ensuring our...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$89K *

Engage in a dynamic 10-week internship, collaborating with investment professionals to conduct fundamental equity research, analyze U.S. companies, and present findings, enhancing your analytical and...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Optimize your career as a Technical Project Manager, overseeing equipment procurement and supply chains. Collaborate with cross-functional teams, manage budgets, and negotiate contracts to ensure proj...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$123K - $184K *

Unlock potential by leading process development for innovative cell therapy solutions. Engage with multidisciplinary teams to enhance drug candidate manufacturing, drive project successes, and ensure...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$144K - $216K *

Drive innovation in Microsoft 365 and AI platforms, leading technical delivery and governance. Balance hands-on execution with strategic oversight to enhance enterprise capabilities and user experienc...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$204K - $306K *

Join a team that's redefining clinical trials by integrating innovative strategies, ensuring safety and scientific integrity while driving efficient execution across cross-functional teams in a fast-p...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $225K *

Grow your career with a senior role in enterprise architecture, shaping technology direction and governance. Collaborate with leaders to develop strategies that drive innovation, reduce complexity, an...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Join a dynamic team as you shape enterprise architecture strategies, drive innovation, and optimize technology governance. Collaborate with senior leaders to align business outcomes with technology di...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Join a team that's shaping the future of data architecture. In this senior role, you'll develop strategies and standards that drive enterprise-level data governance, analytics, and AI capabilities, en...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Lead the charge in shaping enterprise architecture strategies and governance, collaborating with senior stakeholders to drive technology innovation, reduce complexity, and optimize costs across platfo...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Shape the future of technology by developing enterprise architecture strategies, guiding platform evolution, and ensuring alignment with business goals. Collaborate with senior leaders to drive innova...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $180K *

Elevate your career by leading the design and development of scalable software solutions for investment performance measurement. Collaborate with cross-functional teams to drive innovation and enhance...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $225K *

Drive impactful initiatives by leveraging your expertise in finance and analytics. Collaborate across teams to enhance strategies and deliver exceptional results, while fostering a culture of innovati...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $180K *

Elevate your career by leading systems analysis initiatives, driving strategic solutions, and collaborating across teams to enhance operational efficiency and effectiveness in a dynamic environment...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $225K *

Shape the future of investment management by driving innovative strategies and solutions. Collaborate with diverse teams to enhance client experiences and optimize performance across various portfolio...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.