Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$130K - $195K *

Champion enterprise identity governance by leading complex sales cycles, building trusted relationships with senior executives, and connecting security priorities to measurable business outcomes in a...

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$67K - $101K *

Join a dynamic team to drive customer success in cell therapy through expert application support, training, and collaboration. Build relationships with key stakeholders while optimizing workflows and...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $125K *

Champion the management of engineering documentation and CAD activities, ensuring compliance with GMP standards. Collaborate with cross-functional teams to maintain accurate facility records and suppo...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$119K - $178K *

Drive strategic partnerships and lead a cross-functional team to enhance customer satisfaction, optimize service delivery, and identify operational efficiencies while managing high-value relationships...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $140K *

Champion financial insights by owning forecasting and performance analysis. Collaborate globally across Finance, Commercial, and Operations, driving accountability and informed decision-making to fuel...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Join us to support the technical transfer and lifecycle management of biologics separation methods. Leverage your expertise in analytical method development and validation to drive impactful results i...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$104K - $156K *

Join a dynamic team as a technical expert, providing support and training to customers while optimizing applications and troubleshooting complex issues in a collaborative environment. Contribute to sc...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $162K *

Innovate in a strategic sales role, managing key accounts and driving revenue growth. Leverage technical expertise to build relationships and influence decision-making across the F5 solution portfolio...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$169K - $254K *

Lead and optimize the Solutions Engineering team in the Healthcare sector, focusing on technical sales and strategic planning. Drive team performance, manage recruitment, and ensure alignment with com...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$72K - $192K *

Join a team that's dedicated to enhancing client relationships in healthcare. As a trusted advisor, you'll guide clients through workflows, drive feature adoption, and develop strategic plans to maxim...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $134K *

Join a team that's redefining financial planning by creating comprehensive tax strategies. Collaborate with advisors to analyze client data, deliver tailored tax plans, and stay updated on tax laws to...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$129K - $170K *

Champion compliance and legal support across privacy, SaaS contracts, and IP. Collaborate with teams on AI/ML, marketing, and product development while ensuring adherence to regulations and fostering...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$176K - $243K *

Accelerate progress at the forefront of cardiovascular innovation, leading a dynamic team to drive the adoption of advanced imaging solutions in the U.S. market, while fostering strategic partnerships...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Healthcare

$123K - $169K *

Unlock potential by driving regional growth and client engagement in healthcare workforce solutions. Collaborate with sales teams to expand market presence and enhance service offerings, ensuring alig...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$123K - $169K *

Elevate healthcare data integration by leading client engagements, optimizing EHR extracts, and providing strategic guidance. Utilize your SQL expertise to ensure data accuracy and foster strong clien...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $169K *

Unlock potential by driving regional growth and client engagement in healthcare workforce solutions, leveraging expertise in medical imaging and consultative selling to expand market presence and enha...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$176K - $243K *

Unlock potential by driving the adoption of advanced electrophysiology solutions through strategic partnerships, enhancing customer engagement, and fostering relationships with key stakeholders to ens...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$176K - $243K *

Unlock potential by leading strategic initiatives in cardiovascular imaging, driving adoption of advanced technologies, and fostering partnerships to enhance patient care and clinical outcomes across...

RemoteRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Healthcare

$151K - $207K *

Unlock potential by driving strategic growth in healthcare sales, fostering executive relationships, and leading cross-functional teams to achieve commercial targets across Siemens Healthineers' Imagi...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$123K - $169K *

Lead the charge in driving strategic initiatives that enhance talent aggregation and curation, fostering profitable growth and expanding market share through innovative operational solutions...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $224K *

Transform healthcare operations by leveraging your expertise to drive efficiency and improve outcomes. Engage with clients to analyze needs, manage projects, and lead teams in delivering sustainable p...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $148K *

Elevate your career by driving pricing compliance and digitalization initiatives. Collaborate with cross-functional teams to analyze proposals, ensure adherence to financial guidelines, and enhance pr...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in data center innovation, managing critical systems and projects. Collaborate with diverse teams to ensure operational excellence and compliance, while driving technical advancements...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $140K *

Unlock the potential of facilities management by overseeing daily operations, budgets, and vendor relationships. Drive efficiency and customer satisfaction while leading a diverse team to enhance prop...

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$148K - $223K *

Drive the transition of our systems from startup to enterprise scale, ensuring reliability and performance. Collaborate with engineers to enhance infrastructure and lead production excellence in a fas...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.