Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $126,020
$120K - $130K *
Drive the design and implementation of complex software solutions, providing technical leadership and mentorship. Collaborate with cross-functional teams to enhance system architecture and ensure high...
4 days ago
$90K - $120K *
Oversee project portfolios worth $5-$15 million, leading teams through all phases from planning to execution. Drive performance, manage resources, and ensure successful project completion while foster...
4 days ago
$95K - $105K *
Join a dynamic team to coordinate supplier management, drive contract workflows, and ensure compliance in clinical studies. Collaborate with cross-functional teams to enhance supplier processes and su...
4 days ago
Director, Regional Marketing Americas
$160K - $180K *
Drive impactful regional marketing strategies that enhance customer engagement and pipeline growth across the Americas. Collaborate with global teams to create tailored campaigns and support sales ini...
4 days ago
Principal, Financial Operations & Software Asset Management
$137K - $185K *
Join a team that's transforming financial operations by optimizing technology investments. Leverage your expertise to enhance governance, reporting, and insights across cloud services and software ass...
4 days ago
Auditing & Education Consultant - IP facility or IP/OP
$80K - $95K *
Partner with us to evaluate coding accuracy and compliance in healthcare settings. Utilize your expertise in ICD-10, CPT, and HCPCS coding to conduct audits, deliver educational content, and support c...
4 days ago
Critical Mechanical Systems Specialist
$110K - $130K *
Advance mechanical systems readiness by overseeing commissioning, conducting site inspections, and ensuring operational efficiency across critical infrastructure. Collaborate cross-functionally to enh...
4 days ago
$110K - $130K *
Innovate cutting-edge software solutions for Robotics products, focusing on development, performance optimization, and compliance. Collaborate across teams to enhance product functionality and support...
4 days ago
Associate Director, Virtual Health
$115K - $125K *
Drive the development and management of virtual health services, enhancing operational excellence and patient experience while scaling innovative care models across the organization. Lead strategic in...
4 days ago
AI Transformation & Operational Efficiency Manager
$110K - $130K *
Accelerate progress at our organization by leading AI initiatives that transform business processes across departments, focusing on operational efficiency and measurable outcomes in Accounting and Fin...
4 days ago
Sr. Engineering Director, Supply Chain and Order Management Systems
$205K - $240K *
Elevate technology strategy and operations for North America's supply chain, leading engineering teams to optimize platforms and processes. Drive innovation in order management and logistics while ens...
Reposted 4 days ago
Regional Sales Director - Respiratory - East
$234K - $317K *
Drive regional sales strategy and execution across the Respiratory franchise, leading teams to achieve goals and adapt to market needs. Collaborate cross-functionally to enhance performance and build...
4 days ago
Associate Director, Talent Acquisition
$120K - $145K *
Lead the charge in full-cycle recruitment, driving talent acquisition strategies and enhancing candidate experiences in a dynamic biotech environment. Collaborate with hiring managers to build talent...
4 days ago
Senior Application Security Engineer
$120K - $145K *
Transform application security practices by enhancing web, API, and cloud service protections. Collaborate with development teams to remediate vulnerabilities and integrate security into CI/CD workflo...
4 days ago
Senior Associate, Operational Intelligence, Labs
$93K - $138K *
Join a team that's dedicated to enhancing operational efficiency through innovative software solutions. As a key contributor, you'll develop and maintain applications that streamline processes, ensuri...
4 days ago
Account Executive, Managed Services
$80K - $120K *
Engage clients by driving sales of Managed and Professional Services, identifying opportunities, and delivering tailored solutions. Cultivate relationships to exceed revenue targets while leveraging i...
4 days ago
US LBM Market Continuous Improvement Manager
$95K - $115K *
Champion process improvement initiatives to enhance operational efficiency, reduce costs, and drive performance across the organization. Collaborate with leadership to implement Lean and Six Sigma met...
4 days ago
$88K - $105K *
Drive electrical Design Verification Testing for complex aerospace modules, ensuring performance and reliability from development to production. Collaborate with cross-functional teams to enhance test...
4 days ago
Senior Software Security Architect
$135K - $160K *
Advance security integration by leading DevSecOps initiatives, enhancing software delivery, and establishing robust security standards across engineering teams to mitigate risks and improve efficiency...
4 days ago
$68K - $113K *
Lead project coordination efforts by ensuring effective communication and management of materials, schedules, and documentation. Collaborate with teams to streamline processes and enhance project effi...
Reposted 4 days ago
Software/ Systems Engineer III
$82K - $156K *
Contribute to R&D efforts in developing secure, high-performance software solutions for medical devices, ensuring quality and compliance throughout the product lifecycle in a collaborative, hybrid wor...
Reposted 4 days ago
Regional Product Manager (Protein Diagnostics)
$103K - $154K *
Lead the commercial success of a diverse product portfolio across North America. Drive growth, customer adoption, and lifecycle management while collaborating with cross-functional teams to align stra...
4 days ago
Senior Director, Counsel - Litigation, Legal Policy and Strategy (USA Remote role)
$199K - $321K *
Explore a dynamic role shaping litigation and policy strategy in the pharmaceutical sector. Collaborate with senior leaders and external stakeholders to navigate complex legal landscapes, ensuring pat...
4 days ago
Regulatory Affairs Consultant, CMC - Biologics
$110K - $130K *
Drive your career with a pivotal role in CMC regulatory affairs, ensuring compliance for biologics and small molecules. Collaborate across teams to prepare high-quality submissions and strategies, imp...
4 days ago
Director, Strategic Technology & ISV Partnerships
$150K - $178K *
Champion the growth of strategic technology partnerships, leading initiatives across hyperscalers and cloud marketplaces. Drive revenue, adoption, and integration strategies while managing a high-perf...
4 days ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.