Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$98K - $119K *

Lead educational initiatives and support diabetes management by training patients and healthcare professionals on insulin pump therapy, ensuring effective strategies and strong relationships within yo...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$128K - $164K *

Unlock the potential of data by designing and evolving a scalable Lakehouse architecture. Collaborate with cross-functional teams to transform digital and operational data into trusted, self-service a...

4 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Lead the charge in client relationships and delivery for a pioneering offsite service. Take ownership of strategy, execution, and performance to drive AI search visibility outcomes for high-value bran...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Lead the implementation and management of client Speaker Bureau operations, ensuring successful educational programs in the pharmaceutical sector. Collaborate with cross-functional teams to exceed cli...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $145K *

Join us to evaluate and analyze complex commercial real estate appraisals, ensuring compliance with regulatory guidelines. Collaborate with vendors and internal teams to enhance appraisal standards an...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$75K - $100K *

Advance IT security by managing vulnerability scanning tools and processes, ensuring the integrity of USDA systems. Collaborate across teams to implement solutions, troubleshoot issues, and maintain s...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $90K *

Transform your career by providing compassionate care and clinical assessments for the aging population in community settings. Collaborate with interdisciplinary teams to enhance health and independen...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Analyze sales data and trends to support the sales team, optimize performance, and drive strategic decision-making. Collaborate across departments to enhance processes and deliver impactful reports an...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$72K - $127K *

Optimize fulfillment operations by leading a dedicated team to ensure timely order processing, inventory management, and customer satisfaction while driving continuous improvement in efficiency and ef...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Elevate organizational success by leading complex HR projects, ensuring alignment with business goals. Utilize advanced project management skills to drive initiatives that enhance employee experiences...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$160K - $185K *

Join a team that's transforming customer experiences through innovative technical solutions. As a Solutions Architect, you'll bridge business needs with technology, guiding clients from discovery to d...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$78K - $105K *

Elevate your career by leading high-volume restaurant operations and beverage programs. Collaborate with culinary teams to enhance guest experiences through innovative mixology and operational excelle...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$79K - $125K *

Oversee nursing operations, ensuring high-quality, person-centered care while providing clinical leadership and supporting interdisciplinary collaboration on an assigned unit...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $208K *

Join a team that's dedicated to optimizing patient readiness through comprehensive preoperative assessments, education, and collaboration with interdisciplinary teams to enhance surgical outcomes and...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$63K - $102K *

Drive clinical research excellence by managing multiple studies, supervising staff, and liaising with sponsors and regulatory bodies. Optimize trial initiation and patient recruitment while ensuring c...

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Optimize patient care by planning, implementing, and evaluating nursing strategies for diverse patient needs. Collaborate with healthcare teams to ensure quality outcomes while maintaining safety and...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$86K - $208K *

Lead the charge in optimizing patient readiness through comprehensive preoperative assessments, education, and collaboration with interdisciplinary teams to ensure safety and enhance the surgical expe...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$170K - $190K *

Shape the future of oncology research by leading innovative biomarker strategies. Collaborate across teams to drive translational studies and enhance understanding of target biology, supporting precis...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and translating complex financial technology into clear business value for SMEs and growth companie...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Transform the US SME market by owning the full sales cycle, driving revenue growth, and delivering clear business value through innovative financial technology solutions for diverse clients...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Grow your career by owning the full sales cycle in the US SME market. Help technology-enabled businesses navigate complex financial challenges with innovative solutions, driving revenue growth and enh...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and solving complex financial challenges for SMEs through innovative fintech solutions...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$65K - $104K *

Shape the future of patient care as a Radiologic Technologist, combining your radiology expertise with clinical support in a dynamic urgent care environment, ensuring accurate diagnoses and compassion...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $130K *

Partner with us to enhance enterprise Managed File Transfer solutions, focusing on architecture, automation, and security. Drive continuous improvement and support mission-critical services in a dynam...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $175K *

Drive municipal excellence by providing strategic leadership and operational support. Collaborate with departments to enhance services, oversee major projects, and represent the Town Manager in commun...

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.