Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$90K - $110K *

Contribute to impactful restoration projects by managing teams, liaising with clients, and ensuring timely, budget-friendly completion. Leverage your expertise in property restoration to drive success...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $187K *

Elevate client engagement by leading post-payment integrity implementations, ensuring seamless communication and alignment across teams. Drive successful outcomes through expert knowledge and strategi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Join a team that's driving CMC drug development activities across functions. Manage projects with internal and external partners, ensuring timelines and deliverables are met while fostering collaborat...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Help us drive CMC drug development by managing cross-functional teams and external partners. Utilize your project management expertise to ensure timely execution of projects while fostering collaborat...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $143K *

Empower clients through individual, couples, and group therapy while developing personalized treatment plans. Join a collaborative team that values your expertise and offers flexible scheduling option...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$157K - $213K *

Join a team that's transforming security solutions by leading a dynamic sales force, developing strategic partnerships, and driving revenue growth through effective management and innovative client en...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $150K *

Unlock potential by serving as a strategic partner to the President, managing priorities, communications, and operations in a fast-paced environment. Your role is crucial in ensuring efficiency and cl...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$64K - $97K *

Unlock potential by managing global trade classifications, ensuring compliance with customs regulations, and collaborating with cross-functional teams to streamline processes and enhance operational e...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $134K *

Elevate innovation by designing and testing high-speed digital circuit boards for encrypted communications. Collaborate with cross-functional teams to develop cutting-edge technologies and support ope...

4 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Lead the charge in designing and evolving scalable cloud infrastructure, driving architectural strategy, and enhancing operational culture while collaborating with cross-functional teams to meet ambit...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $120K *

Lead the charge in providing comprehensive care management for dually-eligible enrollees, integrating health services and community resources to enhance health outcomes and quality of life through eff...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $100K *

Empower mental health outcomes by providing flexible therapy services, including telehealth. Collaborate with a supportive team while enjoying autonomy in scheduling and a competitive compensation pac...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $240K *

Drive cross-domain visibility and coordination in a dynamic engineering environment. As the sole TPM, you'll ensure programs are on track, dependencies are mapped, and automation enhances efficiency a...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Lead strategic initiatives in utility management and energy systems, ensuring efficient, sustainable operations. Oversee a skilled workforce while implementing decarbonization projects and optimizing...

4 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$90K - $120K *

Lead the integration of health services and community resources to enhance care for dually-eligible enrollees with complex needs. Collaborate with interdisciplinary teams to improve health outcomes an...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Grow your career with a dynamic pharmacy team, providing expert consulting and clinical services while ensuring medication safety and compliance. Mentor colleagues and enhance patient care in a collab...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Optimize quality systems in a dynamic GMP environment, ensuring compliance and supporting continuous improvement initiatives while collaborating across departments to enhance operational excellence...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Explore a dynamic role focused on building relationships with enterprise brands, driving business growth through strategic partnerships, and leveraging AI technologies to optimize processes. Engage in...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Advance your career as a Quality Systems Specialist, ensuring compliance with GMP regulations and managing quality documentation. Collaborate across departments to drive continuous improvement in a dy...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance the administration of Defined Benefit and Retiree Medical plans, ensuring accurate valuations, benefit calculations, and compliance with regulations. Collaborate on special projects while leve...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to enhancing community infrastructure and services. As a key leader, you'll oversee operations, manage personnel, and ensure compliance while driving departmental goals an...

4 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$160K - $180K *

Empower customer success by owning post-sale experiences, driving onboarding, adoption, and renewals. Collaborate with cross-functional teams to ensure every user thrives, turning initial deployments...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Deliver exceptional customer experiences by fostering relationships, guiding onboarding, and ensuring success metrics are met. Play a key role in customer retention and expansion while advocating for...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $180K *

Join our dynamic Payments Growth team to build innovative backend services and APIs that empower Hosts to maximize their earnings and drive business growth. Collaborate across functions to deliver imp...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $180K *

Innovate data-driven strategies to enhance business decision-making and optimize reporting processes. Leverage expertise in BI, CRM Analytics, and Salesforce to deliver actionable insights and support...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.