Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$182K *

Elevate your career by supporting clinical goals through training, coaching, and program implementation. Collaborate with leadership to enhance staff skills and provide direct clinical services, ensur...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $140K *

Join a team that's dedicated to enhancing customer success through strong relationships and strategic account management, driving product adoption and retention for leading companies. Bring your solut...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Information Technology

$70K - $110K *

Lead the charge in driving profitable revenue by educating clients and enhancing visibility of our onsite services across various industries, while collaborating with internal teams to maximize sales...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Shape the future of financial content by crafting engaging, SEO-driven copy that informs and converts. Collaborate with SEO experts and compliance teams to produce clear, compliant content that resona...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $185K *

Innovate at the forefront of machine learning by leading active learning initiatives, enhancing model accuracy, and managing annotation processes. Collaborate with cross-functional teams to drive data...

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $160K *

Lead the charge in driving strategic sales growth within higher education, transforming complex challenges into solutions. Collaborate cross-functionally to enhance market share and establish lasting...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$149K - $198K *

Contribute to the advancement of autonomous vehicle technology by diagnosing complex behaviors and driving solutions through data analysis, cross-subsystem debugging, and technical storytelling. Join...

4 days ago

  •   5 - 7 years exp.  •   Transportation

$149K - $198K *

Champion the investigation and diagnosis of complex AV behaviors, driving solutions autonomously across simulation and on-road environments. Utilize Python and custom tools to enhance diagnostic capab...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Transportation

$100K - $104K *

Manage daily property operations, lead a dedicated team, and drive leasing success while ensuring resident satisfaction and financial performance in a dynamic environment...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Transform patient access by providing education and support to patients, caregivers, and healthcare professionals. Collaborate across teams to enhance therapy access and ensure a seamless experience f...

Waltham, MARemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Help us enhance patient access by providing education and support to patients, caregivers, and healthcare professionals, ensuring a seamless experience with Viridian therapies while collaborating acro...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $149K *

Optimize strategic procurement initiatives in Software and SaaS, enhancing supplier relationships and compliance. Collaborate with stakeholders to drive sourcing solutions that deliver business value...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $168K *

Pioneer application modernization efforts by leading agile teams, driving technical outcomes, and enhancing developer experiences. Collaborate with clients to deliver measurable business results while...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's leading complex global clinical trials, overseeing execution, budgets, and quality. Leverage your expertise in clinical operations to drive study success from planning through close...

4 days ago

  •   8 - 10 years exp.  •   Staffing

$170K - $260K *

Oversee the global Digital Operations Center, driving operational strategy and incident management while leading a multi-site team to enhance monitoring and response capabilities across regions...

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$160K - $200K *

Drive growth by leading strategic partnerships in healthcare tech. Collaborate with executives to shape joint strategies, negotiate impactful deals, and operationalize go-to-market initiatives that en...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $155K *

Champion data-driven insights to enhance Digital Commerce performance. Leverage analytics to optimize pricing, promotions, and strategy for both direct-to-consumer and marketplace channels, driving bo...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Lead the charge in evolving and executing a compelling brand identity that drives measurable results across digital, advertising, and event channels, while leveraging AI tools to enhance creative prod...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Media

$100K - $150K *

Unlock potential by driving B2B sales for innovative payment solutions. Manage the full sales cycle, engage with clients, and leverage technology to enhance business operations. Thrive in a dynamic en...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$116K - $145K *

Join a dedicated team to provide high-quality patient care in a dynamic NICU environment. Utilize your advanced skills to assess, diagnose, and treat patients while collaborating with healthcare profe...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $90K *

Optimize laboratory operations by supporting engineers in testing, troubleshooting, and maintaining equipment. Collaborate with cross-functional teams to enhance efficiency and ensure accurate data co...

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$142K - $202K *

Unlock commercial potential by executing transformation workstreams, collaborating with cross-functional teams, and delivering strategic insights to drive measurable results in a healthcare-focused en...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K *

Unlock potential by providing specialized PM&R services in a collaborative environment. Work closely with interdisciplinary teams to enhance patient outcomes and independence in a skilled nursing faci...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $200K *

Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.