Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,020

Sort By: Relevance

$110K - $130K *

Join us to drive regional sales growth by developing strategies, building a motivated team, and fostering strong customer relationships. Your leadership will be key in achieving financial targets and...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$92K - $125K *

Drive operational excellence in patient access by leading teams, enhancing processes, and fostering collaboration across healthcare facilities. Your leadership will ensure compliance, improve patient...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $130K *

Transform financial strategies by owning revenue forecasting, demand planning, and analytics. Collaborate across functions to drive growth and optimize performance, ensuring data integrity and actiona...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$136K - $204K *

Innovate customer experiences by leading product-led growth initiatives that enhance onboarding, activation, and retention. Collaborate across teams to drive measurable business impact and simplify cu...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $139K *

Drive engineering and project management for the Metropolitan Tunnel Redundancy Program and improvements to water and wastewater facilities, overseeing complex projects while ensuring compliance with...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$96K - $116K *

Pioneer innovative RNA purification processes by executing experiments and collaborating cross-functionally to enhance drug substance development. Drive efficiency and quality in manufacturing through...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Join a dedicated team providing direct clinical care, ensuring high-quality nursing services, and supervising staff to enhance patient outcomes while adhering to safety and quality standards...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$282K - $353K *

Transform the AI landscape by owning technical wins in enterprise deals, leveraging data architecture, and delivering superior AI solutions. Collaborate with executive teams to validate and design inn...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Elevate your career by leading innovative marketing strategies for a dynamic Adult publishing program. Collaborate with teams, manage campaigns, and drive impactful results while mentoring talent and...

4 days ago

  •   5 - 7 years exp.  •   Media

$90K - $155K *

Champion the end-to-end flight test process, collaborating with multi-discipline teams to design, execute, and analyze high-priority tests for advanced aircraft systems, ensuring mission success and o...

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $180K *

Lead the development and execution of imaging strategies for clinical trials, ensuring compliance and innovation in dosimetry methodologies. Collaborate with cross-functional teams to enhance clinical...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$284K - $390K *

Join a team that's driving high-volume B2B demand generation for a leading SaaS product. Collaborate cross-functionally to optimize marketing strategies, enhance sales alignment, and lead a dynamic te...

4 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$284K - $390K *

Join a team that's driving high-volume B2B demand generation for a leading SaaS product. Collaborate cross-functionally to optimize marketing strategies, enhance sales alignment, and lead a dynamic te...

4 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$150K - $225K *

Champion data, cloud, and AI architecture initiatives to enhance enterprise value for private equity firms. Lead assessments, manage client relationships, and translate technical findings into strateg...

4 days ago

  •   8 - 10 years exp.  •   Business Services

$180K - $200K *

Lead financial operations by overseeing accounting, reporting, and compliance. Collaborate with teams to ensure accuracy and efficiency while driving strategic financial guidance and safeguarding the...

4 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$77K - $116K *

Champion financial accuracy by managing journal entries, reconciliations, and forecasting. Collaborate across teams to streamline processes and support audits, contributing to continuous improvement i...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Oversee and enhance tenant experiences while driving financial performance and operational excellence across multiple properties. This role requires strategic relationships with tenants, vendors, and...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead a dynamic team to enhance customer success, drive retention, and maximize revenue growth. Shape strategies and workflows while collaborating cross-functionally to deliver exceptional value and ou...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$144K - $192K *

Champion innovative AI workflows and systems design, collaborating across teams to redefine complex processes. Drive strategic initiatives, enhance operational efficiency, and create AI-ready systems...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $140K *

Drive impactful financial due diligence for M&A activities, collaborating with clients and executives to assess enterprise value and risks. Join a high-performing team dedicated to excellence in deal...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$68K - $131K *

Empower your career by applying your engineering expertise to drive hardware requirements and compliance for advanced defense systems. Collaborate with cross-functional teams to enhance design efficie...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$117K - $170K *

Lead infection prevention initiatives by developing strategies, conducting surveillance, and collaborating with healthcare teams to enhance patient safety and compliance with regulatory standards...

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$85K - $90K *

Grow your career with a pivotal role enhancing corporate nutrition programs. As a Senior Wellness Coordinator, you will drive wellness initiatives, ensuring nutritional compliance while collaborating...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$82K - $100K *

Drive customer success by managing a portfolio of self-serve clients, ensuring effective onboarding, retention, and growth through strategic guidance and product expertise to achieve optimal business...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $95K *

Lead culinary excellence by managing all aspects of food service operations, including menu creation, inventory management, and team leadership, while ensuring safety and sanitation standards are met...

4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.