Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $126,017
$88K - $105K *
Drive exceptional service delivery by leading a motivated team dedicated to operational excellence, managing workforce planning, budgets, and ensuring optimal performance across multiple sites. Empowe...
Reposted 3 days ago
Director - Medical - Clinical Research Physician
$201K - $393K *
Lead the development and execution of global clinical trials for women's health compounds, collaborating with cross-functional teams to shape clinical strategies and ensure compliance with regulatory...
Reposted 3 days ago
$192K - $253K *
Join us to lead the development of data and technology strategies that drive scientific and operational excellence. Oversee a multidisciplinary team and collaborate with stakeholders to deliver impact...
3 days ago
Clinical Specialist, Philadelphia
$80K - $95K *
Empower clinical excellence by delivering expert technical support for neurovascular products. Collaborate with healthcare professionals to enhance patient care, drive product adoption, and ensure suc...
3 days ago
General Manager, Healthcare Practices
$275K - $325K *
Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...
3 days ago
$80K - $90K *
Elevate your career by building and maintaining a network of specialist consultants and physicians. Drive business growth and enhance clinical trial delivery through strong relationships and strategic...
3 days ago
Senior Account Executive - Sports Vertical
$130K - $150K *
Unlock potential by driving new business growth in the sports industry, leveraging your extensive network and sales expertise to close strategic deals and innovate through AI solutions for sports orga...
3 days ago
$69K - $101K *
Manage supplier relationships and procurement processes to ensure seamless production. Collaborate with cross-functional teams to track costs, monitor delivery performance, and resolve material shorta...
3 days ago
Senior Investment Operations Analyst, Private Markets
$73K - $122K *
Pioneer the operational lifecycle of private market investments, enhancing efficiencies through portfolio reporting, compliance, and risk management, while collaborating closely with investment teams...
Reposted 3 days ago
Assistant Director of Development, Harvard College Fund, Reunion Campaigns
$100K - $120K *
Empower alumni engagement through strategic fundraising initiatives, managing reunion campaigns, and collaborating with volunteers to maximize participation and donations. Drive impactful relationship...
3 days ago
Business Development Manager- WA/OR
$95K - $115K *
Accelerate progress at the forefront of commercial fleet sales by driving new customer acquisition and expanding market share through strategic relationship building and consultative selling in a dyna...
3 days ago
Manager, Infrastructure Governance
$125K - $178K *
Accelerate progress at the forefront of cloud security governance, leading a dynamic team to enhance compliance, drive automation, and ensure robust risk management across multi-cloud environments...
3 days ago
Confluent Staff Software Engineer - Kafka
$145K - $175K *
Shape the future of data storage and query solutions by developing scalable, high-performance systems. Collaborate across teams to enhance multi-tenant infrastructure and optimize analytical query eng...
3 days ago
Self-Managed Business Development Manager- East Region
$100K - $120K *
Champion growth by driving new customer acquisition and fleet sales within your territory. Leverage consultative selling and relationship-building to secure small to medium-sized business clients, enh...
3 days ago
Confluent Staff Software Engineer - Kafka
$150K - $180K *
Innovate with us to advance cutting-edge storage and query solutions. As a Staff Software Engineer, you'll tackle complex challenges in multi-tenant infrastructure and analytical query engines, drivin...
3 days ago
$150K - $180K *
Transform sales leadership by building and guiding a high-performing team to drive growth and retention in the AMER region, collaborating across departments to execute strategic initiatives and enhanc...
3 days ago
$90K - $110K *
Champion sales growth and strategic partnerships by developing innovative market strategies, leading customer projects, and ensuring alignment across teams to enhance customer satisfaction and drive r...
3 days ago
Sr. Manager, Patient Access Liaison - South Central (Mississippi, Louisiana, Arkansas, Missouri)
$110K - $130K *
Elevate patient access by providing essential education and support to patients, caregivers, and healthcare professionals. Collaborate across teams to minimize barriers and enhance the experience for...
3 days ago
Deputy Director of Safety Services (SY26-27)
$90K - $105K *
Join a team that's dedicated to fostering safe, student-centered environments. As a senior leader, you'll oversee safety operations, manage personnel, and collaborate with community partners to enhanc...
3 days ago
Sr. Manager, Patient Access Liaison - South Central (Mississippi, Louisiana, Arkansas, Missouri)
$110K - $130K *
Unlock potential by enhancing patient access to therapies through education and support. Collaborate with healthcare professionals and patients to navigate treatment logistics, ensuring a seamless exp...
3 days ago
Product Manager - AI & Automation
$110K - $130K *
Elevate your career by leading AI-driven product innovations that enhance workflows and drive measurable business impact. Collaborate with cross-functional teams to shape user-centric solutions and ac...
3 days ago
Senior Talent Acquisition Partner (Technical)
$120K - $140K *
Elevate your career by leading full-cycle recruiting for technical and business roles. Collaborate with hiring leaders to define needs, source talent, and ensure a seamless hiring experience that driv...
3 days ago
Lead Quantitative UX Researcher, Behavioral Data & Amplitude
$153K - $259K *
Transform user insights into impactful product decisions by leveraging behavioral data analytics. Collaborate with cross-functional teams to enhance understanding of diverse user behaviors and drive i...
3 days ago
Associate Medical Director, Global Safety Physician
$184K - $253K *
Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...
3 days ago
$130K - $160K *
Lead the charge in delivering high-quality, resident-centered nursing care while overseeing operations, staff management, and regulatory compliance to enhance clinical outcomes and ensure safety in a...
3 days ago
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.