Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$80K - $95K *

Manage GMP testing of raw materials and products, ensuring compliance with quality standards. Oversee analytical processes, maintain laboratory equipment, and mentor junior analysts while driving cont...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape your career by leading integrated marketing campaigns that drive customer engagement and new business growth. Collaborate with cross-functional teams to enhance customer adoption and pipeline de...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $134K *

Lead the charge in combating insurance and unemployment fraud by investigating and prosecuting complex cases. Collaborate with law enforcement and agencies to uphold justice and ensure accountability...

2 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$136K - $204K *

Transform platform capabilities by prioritizing standards and integrations, enhancing reliability and developer experience while ensuring cost-effective scalability in AI/ML technologies. Drive stakeh...

2 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$105K - $280K *

Lead the charge in delivering expert patient care in hematology, collaborating with physicians to manage complex cases. Engage in clinical research and enhance patient outcomes through effective care...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$65K - $104K *

Join a dynamic team as you provide essential radiologic services and clinical support in urgent care settings. Your expertise will enhance patient care, ensuring accurate diagnoses and fostering a col...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$73K - $99K *

Transform patient care by leveraging your nursing expertise in a dynamic, supportive environment. Deliver high-quality clinical services, collaborate with a dedicated team, and enhance your profession...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $155K *

Elevate your career by owning critical programs in wafer-scale photonic systems. Collaborate closely with engineering teams to drive projects from concept to completion, ensuring schedules and risks a...

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $183K *

Join a team that's driving growth by acquiring and managing Mid-Market accounts. You'll identify prospects, manage the sales cycle, and build lasting relationships to exceed revenue targets in a dynam...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$88K - $105K *

Champion regional marketing initiatives by aligning with sales to create impactful programs that drive pipeline growth and enhance community engagement. Manage budgets, logistics, and reporting to ens...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$69K - $90K *

Shape the future of wildlife management by overseeing budget formulation and execution. Engage with station managers to ensure compliance with financial regulations while providing essential administr...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$68K - $97K *

Lead operational stability and process standardization for transportation across multiple facilities. Collaborate with planners and logistics partners to enhance delivery performance and resolve disru...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $175K *

Lead the design and delivery of innovative learning and development programs, partnering with stakeholders to enhance professional growth and career pathways for staff and lawyers, while fostering a c...

2 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$85K - $105K *

Shape the future of wastewater construction by overseeing project compliance, monitoring contractor performance, and ensuring adherence to standards. Join a dynamic team dedicated to impactful civil e...

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$155K - $190K *

Reimagine strategic initiatives by leading high-priority projects that drive organizational growth. Collaborate across teams to analyze trends, develop actionable insights, and enhance partnerships, a...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$140K - $215K *

Lead the charge in architecting innovative cloud solutions for top financial firms, serving as a trusted advisor while driving account strategy and technical orchestration to fuel growth in our Enterp...

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Optimize implementation processes by coordinating project activities, ensuring readiness for system rollout, and fostering collaboration among stakeholders to achieve successful outcomes in a dynamic...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to enhancing enterprise IAM governance. You'll oversee access reviews, ensure compliance, and collaborate with cross-functional teams to strengthen security controls and d...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $210K *

Reimagine the iOS experience by leading innovative development efforts that enhance user engagement and drive subscription growth. Collaborate with cross-functional teams to deliver high-quality solut...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Join our team to build and enhance cloud infrastructure that supports vital health records. Collaborate with engineering teams to ensure reliability, security, and efficiency while tackling technical...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Optimize executive operations by providing high-level administrative support, managing complex schedules, coordinating travel, and ensuring seamless communication across teams while handling sensitive...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $108K *

Elevate your career by managing spend categories through strategic sourcing, supplier performance, and contract negotiation. Collaborate with stakeholders to drive continuous improvement and achieve p...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$150K - $180K *

Transform healthcare with cutting-edge AI/ML solutions. Lead architecture, mentor engineers, and drive innovation in LLM-powered products, ensuring safe, scalable insights from complex clinical data...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$131K - $237K *

Shape the future of energy consulting by leading diverse project teams, managing project economics, and collaborating with stakeholders to drive successful outcomes in power generation and distributed...

2 days ago

  •   11 - 15 years exp.  •   Technical Services

$85K - $113K *

Join a team that's dedicated to delivering successful construction projects. Support project management from design to closeout, ensuring effective communication and coordination among stakeholders in...

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.