Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $126,017

Sort By: Relevance

$80K - $95K *

Engage with clients to enhance their cybersecurity resilience by leading incident response efforts, providing expert guidance, and preparing detailed reports to mitigate risks and improve security pos...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$93K - $183K *

Champion innovative drug discovery by identifying and validating therapeutic targets for hematologic cancers. Collaborate in a dynamic lab environment, utilizing advanced molecular and cellular techni...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $246K *

Transform the enterprise network landscape by leading technical strategy, modernization, and integration initiatives. Drive innovation and ensure alignment with business objectives while enhancing pla...

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $118K *

Pioneer innovative drug discovery as you design and conduct preclinical in vivo studies, collaborating with cross-functional teams to evaluate key cancer and immunology therapies in a dynamic, laborat...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $182K *

Unlock your potential by leading innovative process development for synthetic molecules. Collaborate across teams to enhance pharmaceutical manufacturing, optimize processes, and drive technological a...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of oncology by leading clinical development for innovative therapies. Collaborate with cross-functional teams to design protocols, manage projects, and drive data-driven decisions tha...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Lead transformative HR and Payroll projects, enhancing efficiency and compliance. Collaborate with clients to design future-state operating models and drive continuous improvement while managing proje...

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

The Manager - Medicare Advantage Experience at Oliver Wyman will work alongside industry leaders and contribute to various client projects, particularly in the Medicare Advantage sector. This role inv...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$97K - $133K *

Lead the evolution of transaction systems by bridging business and tech, prioritizing features, and driving user-centered design to enhance scalability and automation in product management...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$160K - $246K *

Champion innovative IAM solutions by designing secure software and optimizing SaaS services. Collaborate across teams to embed security practices, conduct threat modeling, and enhance monitoring syste...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$225K - $250K *

Drive financial management and reporting for private equity real estate funds, ensuring accuracy and compliance. Collaborate with cross-functional teams to support fund operations, investor relations...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Champion client relationships by developing strategies that enhance satisfaction, retention, and profitability. Lead a team to execute action plans, manage service quality, and drive business growth t...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $145K *

Transform statewide payroll engagement and change management by leading strategic initiatives, fostering collaboration, and enhancing communication across departments to ensure effective payroll admin...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$75K - $94K *

Shape exceptional client experiences by leading AV production and design projects. Collaborate across sectors to ensure successful event execution while building lasting relationships and maintaining...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$90K - $157K *

Drive automation engineering excellence by designing, developing, and maintaining robust enterprise automation solutions across Banking and Payments. Collaborate with global teams to enhance testing f...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the development of AI-driven document extraction solutions, ensuring accuracy and efficiency. Collaborate with cross-functional teams to prioritize features and manage product roadmaps, driving i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$376K - $500K+*

Join a team that's shaping the financial future of a leading institution. As a strategic leader, you'll oversee financial planning, budgeting, and compliance, ensuring sustainable growth and integrity...

2 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$86K - $109K *

Join a team that's shaping the future of fire protection engineering by evaluating and designing innovative fire alarm systems, ensuring compliance with safety codes, and collaborating on complex proj...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$122K - $150K *

Unlock potential by leading IT sourcing and vendor management strategies, ensuring alignment with business objectives, and fostering collaboration with senior IT leaders to optimize organizational eff...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$193K - $238K *

Unlock potential by driving enterprise sales strategies to acquire new clients. Engage with C-level executives, manage key accounts, and exceed revenue goals while advocating for innovative EHS soluti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$122K - $150K *

Shape IT sourcing strategies and vendor management processes to align with business goals, managing complex contracts and relationships within the IT organization while fostering collaboration and dri...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$95K - $181K *

Join a team that's driving operational excellence in manufacturing. This role involves coordinating with various functional partners to ensure timely integration of resources, enhancing program develo...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$68K - $131K *

Unlock your potential as a Senior System Administrator, supporting advanced IT solutions in a dynamic environment. Collaborate with cybersecurity experts and tackle complex technical challenges while...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$95K - $181K *

Elevate your career by providing comprehensive contract management support for complex U.S. Government contracts. Collaborate with cross-functional teams to ensure compliance and drive successful cont...

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.