Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,893

Sort By: Relevance

$120K - $145K *

Lead the charge in managing our growth roadmap, ensuring seamless integration across marketing, data, and engineering teams while maintaining data integrity and optimizing performance metrics for succ...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Elevate your career by driving innovative structural designs for light-gauge and cold-formed steel systems in modular and prefabricated buildings, ensuring compliance with California codes and enhanci...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$170K *

Lead the charge in engineering excellence by managing API, Web, and Mobile teams, ensuring seamless execution and alignment with product goals while driving technical ownership and fostering team grow...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in innovative immunology research, developing novel methods for pathogenic cell depletion. Collaborate across teams to drive discovery and optimize therapeutic strategies, contributing...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $150K *

Join a compassionate team dedicated to providing gentle end-of-life care for pets in their homes. Enjoy a flexible schedule, meaningful interactions, and the opportunity to make a lasting impact on fa...

Today

  •   Less than 5 years exp.  •   Healthcare

$85K - $105K *

Join a team that's dedicated to enhancing the quality of care in our Home Health and Private Duty department. Oversee operations, support caregivers, and ensure compliance while fostering teamwork and...

Today

  •   Less than 5 years exp.  •   Healthcare

$250K - $400K *

Shape the future of AI by designing evaluation frameworks and feedback systems that enhance model performance. Collaborate across teams to translate research into scalable solutions, driving impactful...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$100K *

Drive growth in the childcare division by leading a team of specialists, enhancing client relationships, and refining operational processes to maximize program impact and scalability...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Reimagine banking operations by managing product roadmaps for Time Deposits and related applications. Collaborate with cross-functional teams to enhance customer experiences while ensuring compliance...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$93K - $150K *

Drive impactful market research initiatives by leading client relationships, managing complex projects, and mentoring teams. Collaborate with stakeholders to deliver strategic insights that enhance de...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$122K - $163K *

Empower clinical development through scientific leadership in biomarker and bioanalytical strategies, guiding assay design, CRO oversight, and regulatory submissions in a fast-paced environment...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $222K *

Transform strategic sourcing by evaluating early-stage assets and opportunities. Collaborate cross-functionally to enhance Formation Bio's business development pipeline and drive asset growth in a tec...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $102K *

Lead ERP customization and implementation efforts, collaborating with stakeholders to align business needs with technical solutions. Drive project governance, manage client relationships, and ensure c...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$170K - $185K *

Champion innovative software solutions by leading complex projects, mentoring engineers, and driving technical excellence across teams. Collaborate on strategic initiatives to enhance reliability and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $115K *

Join a team that's driving sustainability initiatives across diverse sectors. Collaborate with leadership to implement innovative strategies in decarbonization, biodiversity, and compliance, ensuring...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $150K *

Champion integrated project management for complex pharmaceutical advertising, leading cross-functional teams to ensure timely delivery within scope and budget while mentoring junior staff and enhanci...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$234K - $300K *

Transform customer operations by leading cross-functional teams, driving strategic alignment, and enhancing operational efficiency. Leverage your leadership skills to integrate Technical, Renewals, an...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$122K - $210K *

Redefine sales leadership in building automation by coaching teams, shaping strategies, and driving growth. Oversee key initiatives to maximize order intake and margin, while cultivating strong client...

Reposted today

  •   5 - 7 years exp.  •   Business Services

$136K - $204K *

Drive the development of AI and technology certification programs for law schools, enhancing legal education engagement and establishing Clio as a trusted partner in the academic community through inn...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$135K - $150K *

Join a dynamic team as you drive profitable growth through business development, underwriting expertise, and relationship management in the wholesale insurance marketplace, while building a diverse an...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $179K *

Unlock potential by partnering with leadership to enhance workforce effectiveness, engagement, and inclusion. Drive People Practices strategies, coach advisors, and leverage metrics to foster a thrivi...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$135K - $150K *

Transform your career by driving profitable growth through business development, underwriting expertise, and relationship management in the wholesale insurance marketplace. Collaborate with agents and...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$180K - $250K *

Drive business development in Robotics and Manufacturing sectors, securing pre-sales and strategic partnerships. Lead the sales cycle, develop compelling business cases, and build key relationships to...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the evolution of product security by managing engineering teams and shaping secure development practices while collaborating across departments to improve overall security posture and compliance...

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.