Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,888

Sort By: Relevance

$90K - $180K *

Elevate workforce management by driving talent acquisition and retention strategies, enhancing associate experiences, and fostering an inclusive workplace culture through effective leadership and data...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$145K - $185K *

Transform drug discovery by leveraging your expertise in computational chemistry and AI/ML. Collaborate across multidisciplinary teams to drive innovative solutions from hit identification to clinical...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$86K - $116K *

Drive exceptional patient care by ensuring accurate prescription fulfillment and fostering strong relationships with healthcare stakeholders. Collaborate with management to achieve operational goals w...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Transform customer HR environments by implementing and optimizing AI solutions. Collaborate with clients to configure integrations, troubleshoot issues, and enhance workflows, ensuring seamless deploy...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$185K - $315K *

Join us to shape strategic financial planning and analysis, leveraging AI to enhance forecasting and decision-making. This high-impact role collaborates with executives, driving insights that align wi...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$95K - $120K *

Collaborate with a dynamic team to innovate and develop cutting-edge mechanical designs. Engage in hands-on prototyping and testing, leveraging your engineering expertise to bring transformative produ...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $135K *

Join a team that drives precision in pension payroll administration, ensuring compliance and operational excellence across diverse defined benefit plans while fostering client partnerships and managin...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $188K *

Inspire the next generation of lighting designers through innovative teaching and collaboration. This role encompasses curriculum development, mentorship, and active participation in production, foste...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $124K *

Champion innovative project management solutions, guiding teams through configuration, product demonstrations, and stakeholder collaboration to deliver value-driven consulting services that adapt to e...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $215K *

Champion strategic sales operations by guiding executive decisions, enhancing pipeline insights, and driving cross-functional initiatives to optimize performance and execution across the Law Enforceme...

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Take ownership of SSP partnerships to optimize programmatic supply, enhance monetization, and ensure compliance. Collaborate with cross-functional teams to drive revenue growth and improve inventory q...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$70K - $110K *

Champion the resolution of complex Tier 3 auto claims, leveraging expertise in investigation, liability assessment, and negotiation to ensure effective outcomes while serving as the primary contact fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$171K - $257K *

Transform user experiences by leading design strategies for digital health products. Collaborate with cross-functional teams to create intuitive interfaces that enhance user engagement and satisfactio...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by leading the strategic growth of our Attorney Banking Division. Drive business development, mentor a remote team, and enhance client experiences while achieving personal producti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $215K *

Elevate commercial success by leading pricing and contracting strategies across North America. Drive governance, optimize deals, and foster collaboration with cross-functional teams to enhance profita...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $135K *

Shape client relationships and drive growth by expanding existing accounts, identifying service opportunities, and delivering tailored managed security solutions that enhance compliance and risk manag...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$138K - $173K *

Deliver strategic solutions through ownership of critical financial systems, enhancing operational workflows, and driving efficiency in financial processes by leveraging advanced Oracle EPM technologi...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$222K - $278K *

Join a dynamic team to drive enterprise sales, transforming industries through innovative technology. Engage with C-level executives, manage complex deals, and build lasting relationships that impact...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $200K *

Lead the innovation and implementation of cutting-edge technology solutions to enhance data governance, optimize operations, and improve workplace experiences while managing a high-performing team of...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $180K *

Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$136K - $204K *

Architect robust data solutions by designing scalable ingestion, transformation, and delivery patterns. Champion automation and security across platforms while enhancing team efficiency and reliabilit...

2 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$167K - $222K *

Join a team that's redefining defense technology through advanced systems engineering. Leverage your expertise in algorithm development and modeling to create robust command and control solutions that...

2 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $145K *

Transform client needs into innovative solutions as a Senior Solutions Architect. Collaborate with sales and delivery teams to design, implement, and present tailored IT services, ensuring alignment w...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.