Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,888

Sort By: Relevance

$100K *

Optimize Residential Recovery Services by providing strategic leadership and operational oversight. Ensure high-quality clinical care, regulatory compliance, and staff development while aligning with...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by providing empathetic pharmacy consulting and clinical services. Manage pharmacy operations, enhance patient experiences, and lead staff development while ensuring compliance with r...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $250K *

Drive commercial growth by establishing a new development function, enhancing seller effectiveness, and leveraging analytics and technology to transform strategies into measurable results across multi...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $140K *

Join a dynamic pharmacy team to provide exceptional patient care through medication management, clinical services, and staff development. Enhance patient experiences while ensuring compliance and oper...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$143K - $273K *

Lead the charge in designing and developing innovative software solutions for advanced storage systems. Collaborate with cross-functional teams to enhance product features and mentor junior engineers...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading the strategy and roadmap for a connected care platform, enhancing patient experiences through integrated technology solutions in healthcare settings. Drive product vision...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $148K *

Lead the charge in transforming complex healthcare supply chain data into actionable insights, dashboards, and models that drive performance improvement and support strategic consulting engagements fo...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a dynamic team to elevate client relationships and deliver exceptional wealth management services, supporting key investment strategies and ensuring client satisfaction with detailed financial an...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Accelerate our events strategy by managing end-to-end logistics, driving engagement, and optimizing performance to enhance customer relationships and sales opportunities across diverse sectors...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $293K *

Join a team that's dedicated to advancing oncology care through collaboration and leadership. As a key member of an interdisciplinary team, you'll manage outpatient care, providing essential support a...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$62K - $100K *

Drive SaaS conversion initiatives by collaborating with teams to assess risks, readiness, and opportunities. Engage with customers to facilitate migrations and ensure effective communication throughou...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $135K *

Drive global custody excellence by managing strategic banking relationships, optimizing service delivery, and ensuring compliance across international markets. Collaborate with cross-functional teams...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $158K *

Transform patient care by leading pharmacy operations, ensuring safety, and enhancing team performance. As a Staff Pharmacist, you'll deliver compassionate service, manage inventory, and support healt...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Engage with clients to enhance their cybersecurity resilience by leading incident response efforts, providing expert guidance, and preparing detailed reports to mitigate risks and improve security pos...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$93K - $183K *

Champion innovative drug discovery by identifying and validating therapeutic targets for hematologic cancers. Collaborate in a dynamic lab environment, utilizing advanced molecular and cellular techni...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $246K *

Transform the enterprise network landscape by leading technical strategy, modernization, and integration initiatives. Drive innovation and ensure alignment with business objectives while enhancing pla...

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $118K *

Pioneer innovative drug discovery as you design and conduct preclinical in vivo studies, collaborating with cross-functional teams to evaluate key cancer and immunology therapies in a dynamic, laborat...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$116K - $182K *

Unlock your potential by leading innovative process development for synthetic molecules. Collaborate across teams to enhance pharmaceutical manufacturing, optimize processes, and drive technological a...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of oncology by leading clinical development for innovative therapies. Collaborate with cross-functional teams to design protocols, manage projects, and drive data-driven decisions tha...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Lead transformative HR and Payroll projects, enhancing efficiency and compliance. Collaborate with clients to design future-state operating models and drive continuous improvement while managing proje...

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

The Manager - Medicare Advantage Experience at Oliver Wyman will work alongside industry leaders and contribute to various client projects, particularly in the Medicare Advantage sector. This role inv...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$97K - $133K *

Lead the evolution of transaction systems by bridging business and tech, prioritizing features, and driving user-centered design to enhance scalability and automation in product management...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$160K - $246K *

Champion innovative IAM solutions by designing secure software and optimizing SaaS services. Collaborate across teams to embed security practices, conduct threat modeling, and enhance monitoring syste...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$225K - $250K *

Drive financial management and reporting for private equity real estate funds, ensuring accuracy and compliance. Collaborate with cross-functional teams to support fund operations, investor relations...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.