Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,888

Sort By: Relevance

$150K - $180K *

Innovate with us to advance cutting-edge storage and query solutions. As a Staff Software Engineer, you'll tackle complex challenges in multi-tenant infrastructure and analytical query engines, drivin...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Transform sales leadership by building and guiding a high-performing team to drive growth and retention in the AMER region, collaborating across departments to execute strategic initiatives and enhanc...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Champion sales growth and strategic partnerships by developing innovative market strategies, leading customer projects, and ensuring alignment across teams to enhance customer satisfaction and drive r...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Elevate patient access by providing essential education and support to patients, caregivers, and healthcare professionals. Collaborate across teams to minimize barriers and enhance the experience for...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Join a team that's dedicated to fostering safe, student-centered environments. As a senior leader, you'll oversee safety operations, manage personnel, and collaborate with community partners to enhanc...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Unlock potential by enhancing patient access to therapies through education and support. Collaborate with healthcare professionals and patients to navigate treatment logistics, ensuring a seamless exp...

Waltham, MARemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by leading AI-driven product innovations that enhance workflows and drive measurable business impact. Collaborate with cross-functional teams to shape user-centric solutions and ac...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $140K *

Elevate your career by leading full-cycle recruiting for technical and business roles. Collaborate with hiring leaders to define needs, source talent, and ensure a seamless hiring experience that driv...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$153K - $259K *

Transform user insights into impactful product decisions by leveraging behavioral data analytics. Collaborate with cross-functional teams to enhance understanding of diverse user behaviors and drive i...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$184K - $253K *

Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead the charge in delivering high-quality, resident-centered nursing care while overseeing operations, staff management, and regulatory compliance to enhance clinical outcomes and ensure safety in a...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Unlock potential by driving enterprise sales through consultative approaches, managing complex deals with multiple stakeholders, and leveraging a proven sales methodology to achieve targets and foster...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$181K - $345K *

Join a team that's driving innovation in engineering program management. Lead complex, cross-functional programs through the entire product lifecycle, ensuring timely delivery and budget adherence whi...

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$98K - $134K *

Join our team to drive revenue growth by acquiring new accounts and fostering relationships. You'll engage with key prospects, execute business development strategies, and collaborate cross-functional...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$165K - $200K *

Transform captive program management by driving portfolio growth, enhancing underwriting practices, and fostering strong partner relationships. Join a dynamic team to shape innovative solutions and de...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$94K - $102K *

Drive your career with a hands-on role coordinating customer security and AI assessments. Collaborate across teams to streamline processes, enhance communication, and ensure timely responses, enabling...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$167K - $372K *

Drive growth by building and scaling a private equity partnerships program, enhancing existing relationships, and creating commercial opportunities through strategic engagement and collaboration with...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Lead the automation of invoice processes, optimizing Accounts Payable operations while driving strategic initiatives. Collaborate across departments to enhance efficiency and support a high-performing...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$133K - $161K *

Transform your career by overseeing inpatient clinical operations, driving strategic initiatives, and enhancing resource utilization across multiple hospitals. Collaborate with leadership to ensure op...

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$90K - $130K *

Advance system integration testing by developing and managing HIL/SIL environments, ensuring compliance with quality standards, and collaborating with cross-functional teams to enhance product reliabi...

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $235K *

Lead the transformation of research models into deployable inference services, optimizing machine learning pipelines for large-scale image processing. Collaborate with cross-functional teams to enhanc...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a pioneering team driving sales growth in the data center segment. You'll develop strategies, manage key accounts, and lead a virtual team to enhance customer satisfaction and deliver value in a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$111K - $167K *

Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$124K - $158K *

Elevate patient care by supporting pharmacy operations across the district. As a key player, you'll ensure safe dispensing, manage pharmacy teams, and enhance patient experiences while embodying our v...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Champion the resolution of complex technical issues for clients, leveraging expertise in Linux, networking, and cloud environments. Collaborate with teams to enhance service delivery and operational c...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.