Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$110K - $130K *

Lead the development and delivery of innovative digital products, collaborating with cross-functional teams to align strategies with business goals and enhance customer experiences through data-driven...

Yesterday

  •   5 - 7 years exp.  •   Media

$75K - $90K *

Join a team that's dedicated to providing high-quality, safe nursing care while coordinating patient treatment and supervising staff. This role emphasizes clinical excellence and resource management t...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Grow your career by driving revenue growth in the acute care market through new customer acquisition and account expansion. Manage the full sales lifecycle while collaborating with internal teams to d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$228K - $342K *

Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $93K *

Accelerate progress at customer success by building strong relationships, driving product adoption, and ensuring customer satisfaction. Collaborate cross-functionally to resolve issues and enhance cus...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$105K - $120K *

Engage with public health labs to enhance customer satisfaction and drive sales. Collaborate with cross-functional teams to execute market strategies and foster relationships with key opinion leaders...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $252K *

Lead the charge in advancing risk management and investment analytics, conducting in-depth assessments and developing innovative models to enhance portfolio performance and decision-making for institu...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $195K *

Strategize the future of Transmission Engineering by leading a dynamic team, enhancing operational efficiency, and expanding client relationships while ensuring compliance with industry standards and...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive quality assurance for innovative conversational AI solutions, ensuring reliability and accuracy across voice applications and customer engagement platforms. Collaborate with cross-functional tea...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $150K *

Lead the charge in developing innovative 3D printing materials, managing complex projects from concept to launch. Collaborate with cross-functional teams and external partners to ensure timely deliver...

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $150K *

Drive the development and launch of innovative 3D printing materials, coordinating cross-functional teams and external partners to ensure timely delivery and quality. Leverage project management exper...

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$132K - $251K *

Transform the future of air traffic navigation by leading cross-functional teams, managing full lifecycle programs, and ensuring delivery excellence while fostering strong customer relationships in a...

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$99K - $120K *

Join a team that's redefining innovation in software engineering for critical facilities. You'll design and deliver cutting-edge applications and data solutions, driving projects from concept to deplo...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Technical Services

$95K *

Lead the development and implementation of clinical goals, ensuring quality care and compliance. Collaborate with staff to enhance patient services and oversee program operations, fostering a supporti...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$113K - $125K *

Drive product strategy and outcomes in a senior role, focusing on educational equity and data-driven impact. Collaborate with cross-functional teams to shape product direction, prioritize initiatives...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform the future of capital projects by leading strategic planning, design, and execution of major initiatives that enhance operational effectiveness and guest experience while ensuring alignment...

Yesterday

  •   8 - 10 years exp.  •   Hospitality & Recreation

$95K - $115K *

Lead the charge in optimizing operational activities within the DHMS program, ensuring compliance and driving continuous improvement. Collaborate with stakeholders to implement effective strategies an...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Drive network operations and projects in a collaborative environment, ensuring seamless delivery of services while engaging with clients and vendors to optimize solutions and support...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$109K - $174K *

Optimize clinical engineering processes to drive innovative orthopedic solutions, collaborating with cross-functional teams to enhance surgical robotics and navigation, ensuring alignment with clinica...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Create impactful data governance strategies to manage master data effectively. Lead teams to optimize data systems, enhancing organizational decision-making while ensuring compliance and high-quality...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$109K - $174K *

Join a dynamic team driving innovation in surgical robotics and navigation for orthopedics. Leverage your clinical expertise to transform early-stage ideas into impactful medical devices, enhancing pa...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Join a dynamic team driving Master Data Management strategies to enhance data governance and operational efficiency across global orthopedic initiatives. Lead cross-functional collaboration to ensure...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Advance your career in a dynamic 12-month clinical immersion program, gaining hands-on experience in pediatric hematology/oncology and stem cell transplant while collaborating with a multidisciplinary...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $140K *

Join a dynamic team as you drive sales in the public safety sector, managing a diverse territory. Leverage AI tools to identify opportunities, close deals, and build lasting relationships with agencie...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.