Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.
Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.
Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.
Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.
Average Salary: $125,890
$110K - $130K *
Lead the development and delivery of innovative digital products, collaborating with cross-functional teams to align strategies with business goals and enhance customer experiences through data-driven...
Yesterday
Registered Nurse (RN) - Med Surg
$75K - $90K *
Join a team that's dedicated to providing high-quality, safe nursing care while coordinating patient treatment and supervising staff. This role emphasizes clinical excellence and resource management t...
Yesterday
Business Development Manager - Acute
$95K - $115K *
Grow your career by driving revenue growth in the acute care market through new customer acquisition and account expansion. Manage the full sales lifecycle while collaborating with internal teams to d...
Yesterday
Senior Director, Head of R&D Governance and Portfolio Management
$228K - $342K *
Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...
Yesterday
$76K - $93K *
Accelerate progress at customer success by building strong relationships, driving product adoption, and ensuring customer satisfaction. Collaborate cross-functionally to resolve issues and enhance cus...
Yesterday
Account Manager, Life Science, Public Health Labs (East Coast)
$105K - $120K *
Engage with public health labs to enhance customer satisfaction and drive sales. Collaborate with cross-functional teams to execute market strategies and foster relationships with key opinion leaders...
Yesterday
Portfolio Design, Analytics, & Risk Principal
$126K - $252K *
Lead the charge in advancing risk management and investment analytics, conducting in-depth assessments and developing innovative models to enhance portfolio performance and decision-making for institu...
Reposted yesterday
Director, Transmission Engineering
$185K - $195K *
Strategize the future of Transmission Engineering by leading a dynamic team, enhancing operational efficiency, and expanding client relationships while ensuring compliance with industry standards and...
Reposted yesterday
Quality Assurance Engineer - Conversational AI & Voice Testing
$95K - $115K *
Drive quality assurance for innovative conversational AI solutions, ensuring reliability and accuracy across voice applications and customer engagement platforms. Collaborate with cross-functional tea...
Yesterday
$100K - $150K *
Lead the charge in developing innovative 3D printing materials, managing complex projects from concept to launch. Collaborate with cross-functional teams and external partners to ensure timely deliver...
Yesterday
$100K - $150K *
Drive the development and launch of innovative 3D printing materials, coordinating cross-functional teams and external partners to ensure timely delivery and quality. Leverage project management exper...
Yesterday
$100K - $120K *
Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...
Yesterday
Senior Product/Program Manager (Hybrid)
$132K - $251K *
Transform the future of air traffic navigation by leading cross-functional teams, managing full lifecycle programs, and ensuring delivery excellence while fostering strong customer relationships in a...
Yesterday
Software Engineer - Special Projects and Innovation
$99K - $120K *
Join a team that's redefining innovation in software engineering for critical facilities. You'll design and deliver cutting-edge applications and data solutions, driving projects from concept to deplo...
Yesterday
Clinical Supervisor - Sign on Bonus Eligible
$95K *
Lead the development and implementation of clinical goals, ensuring quality care and compliance. Collaborate with staff to enhance patient services and oversee program operations, fostering a supporti...
Yesterday
$113K - $125K *
Drive product strategy and outcomes in a senior role, focusing on educational equity and data-driven impact. Collaborate with cross-functional teams to shape product direction, prioritize initiatives...
Yesterday
Director, Capital Projects, Planning & Analysis
$110K - $130K *
Transform the future of capital projects by leading strategic planning, design, and execution of major initiatives that enhance operational effectiveness and guest experience while ensuring alignment...
Yesterday
$95K - $115K *
Lead the charge in optimizing operational activities within the DHMS program, ensuring compliance and driving continuous improvement. Collaborate with stakeholders to implement effective strategies an...
Yesterday
$88K - $105K *
Drive network operations and projects in a collaborative environment, ensuring seamless delivery of services while engaging with clients and vendors to optimize solutions and support...
Yesterday
$109K - $174K *
Optimize clinical engineering processes to drive innovative orthopedic solutions, collaborating with cross-functional teams to enhance surgical robotics and navigation, ensuring alignment with clinica...
Yesterday
Director, Global Master Data Management & Data Governance
$150K - $258K *
Create impactful data governance strategies to manage master data effectively. Lead teams to optimize data systems, enhancing organizational decision-making while ensuring compliance and high-quality...
Reposted yesterday
$109K - $174K *
Join a dynamic team driving innovation in surgical robotics and navigation for orthopedics. Leverage your clinical expertise to transform early-stage ideas into impactful medical devices, enhancing pa...
Yesterday
Director, Global Master Data Management & Data Governance
$150K - $258K *
Join a dynamic team driving Master Data Management strategies to enhance data governance and operational efficiency across global orthopedic initiatives. Lead cross-functional collaboration to ensure...
Yesterday
Nurse Practitioner or PA, Oncology/SCT Immersion Program
$95K - $115K *
Advance your career in a dynamic 12-month clinical immersion program, gaining hands-on experience in pediatric hematology/oncology and stem cell transplant while collaborating with a multidisciplinary...
Yesterday
Key Account Leader, Small Cities East
$110K - $140K *
Join a dynamic team as you drive sales in the public safety sector, managing a diverse territory. Leverage AI tools to identify opportunities, close deals, and build lasting relationships with agencie...
Yesterday
What types of $100,000+ jobs can I find in Massachusetts?
Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.
Where in Massachusetts can I find high-paying jobs?
Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.
How can I search for Massachusetts jobs paying $100,000 or more?
Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.
Are Massachusetts jobs on Ladders vetted?
Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.