Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,893

Sort By: Relevance

$175K - $185K *

Lead the strategy and development of innovative analytics and AI solutions, collaborating with cross-functional teams to transform complex healthcare data into actionable insights that drive measurabl...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$210K - $280K *

Shape the future of quantitative investment research by leading innovative modeling and analysis for private markets. Collaborate with diverse teams to generate actionable insights that enhance invest...

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  •   5 - 7 years exp.  •   Finance & Insurance

$87K - $123K *

Drive the reliability and performance of a cutting-edge research platform. Collaborate with teams to enhance operational tooling, automate processes, and ensure system dependability as user needs evol...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$133K - $249K *

Drive acquisition lifecycle support and strategic evaluations in M&A. Collaborate with cross-functional teams to conduct data analyses, monitor competitor activities, and enhance the investment thesis...

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Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive operational excellence by leading strategic initiatives, enhancing client partnerships, and fostering a high-performing team in a rapidly evolving security services environment. Shape the future...

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  •   5 - 7 years exp.  •   Staffing

$110K *

Empower a dynamic mobile team by providing 24/7 AOG support, coordinating maintenance events, and ensuring regulatory compliance while fostering strong customer relationships and maintaining operation...

United StatesRemote

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  •   Less than 5 years exp.  •   Aerospace & Defense

$87K - $95K *

Unlock your potential as a key member of our Energy & Sustainability team, managing utility billing processes and ensuring seamless communication across stakeholders to drive efficiency and accuracy i...

United StatesRemote

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  •   Less than 5 years exp.  •   Real Estate & Construction

$151K - $202K *

Drive innovation by leading the design and development of advanced optical subsystems for biomedical devices. Collaborate with cross-functional teams to ensure integration and performance, while mento...

Today

  •   8 - 10 years exp.  •   Healthcare

$230K - $280K *

Unlock potential by leading the design and implementation of AI solutions, ensuring secure, maintainable applications at enterprise scale while mentoring teams and collaborating across functions to dr...

Today

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Elevate your career with a dynamic role that blends design and technical expertise, guiding projects from concept to completion while collaborating with clients and teams to deliver innovative solutio...

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $170K *

Grow your career with a dynamic team as you lead the Osmometer portfolio, driving market share growth and innovation through strategic planning, customer engagement, and cross-functional collaboration...

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $105K *

Engineer innovative solutions for consumable manufacturing processes, enhancing safety, quality, and efficiency. Collaborate cross-functionally to resolve production issues and implement improvements...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join us to lead the Revenue Cycle Management team, overseeing billing processes, managing staff, and ensuring compliance with healthcare regulations while driving operational efficiency and financial...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$72K - $99K *

Transform patient care by providing therapeutic support in home health settings. Collaborate with families to enhance recovery and maintain functionality, ensuring a positive impact on patients' lives...

Today

  •   Less than 5 years exp.  •   Healthcare

$101K - $137K *

Join a team that's dedicated to delivering exceptional home-based physical therapy services. Collaborate with patients and families to enhance recovery and well-being while working under the guidance...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $150K *

Unlock potential by driving revenue growth through strategic sales initiatives in data center security solutions. Collaborate with cross-functional teams to develop customer relationships and achieve...

United StatesRemote

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  •   Less than 5 years exp.  •   Enterprise Technology

$155K - $220K *

Champion a dynamic actuarial team to drive strategic pricing, reserving, and modeling initiatives. Leverage your expertise to influence business decisions and enhance organizational performance while...

United StatesRemote

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  •   8 - 10 years exp.  •   Finance & Insurance

$138K - $200K *

Shape the future of data architecture by designing scalable solutions that drive analytics and business decision-making. Collaborate with cross-functional teams to implement efficient data models and...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $120K *

Partner with us to lead financial management for Care in Action, overseeing budgeting, reporting, and compliance across multiple entities. Drive strategic financial stewardship while ensuring organiza...

United StatesRemote

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  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$127K - $187K *

Unlock potential by transforming data into actionable insights that drive strategic decisions in communications. Collaborate across teams to enhance measurement frameworks and reporting, ensuring impa...

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Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $149K *

Optimize data governance by enhancing metadata quality, ownership, and compliance. Collaborate with stakeholders to ensure effective governance processes and support data quality initiatives, leveragi...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $90K *

Engage with clients to deliver tailored insights and solutions, managing projects from inception to completion. Collaborate with teams to maximize outcomes while developing critical business skills in...

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  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Oversee the Dynamics 365 business in the US, driving growth, profitability, and team development while ensuring delivery excellence and strategic customer engagement for sustainable success...

United StatesRemote

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  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Grow your career with a dynamic role focused on driving revenue and expanding relationships in the environmental sector. Utilize consultative selling and strategic prospecting to achieve objectives ac...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform enterprise ERP implementations by configuring and managing Infor M3 CloudSuite environments. Collaborate with IT teams to ensure operational readiness and security, driving successful projec...

United StatesRemote

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  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.