Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$73K - $110K *

Champion compliance excellence by managing HR programs, ensuring alignment with laws, and enhancing processes. Collaborate across teams to minimize risk and support organizational growth while navigat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Unlock potential by leading complex subrecipient programs, ensuring compliance, and fostering collaboration across teams to drive impactful opioid response initiatives in Illinois. This role demands s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$198K - $233K *

Shape AI product strategy by synthesizing trends, customer needs, and tech capabilities. Collaborate with engineering and design to drive innovation, enabling AI solutions that deliver genuine custome...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Build relationships with personal injury attorneys to drive referrals for settlement planning and wealth management. Leverage your expertise to develop sales strategies and enhance brand awareness whi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$79K - $127K *

Unlock insights into medical cost trends by leveraging data analytics. Collaborate with cross-functional teams to develop strategic recommendations, track program outcomes, and present findings clearl...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$163K - $297K *

Join a dynamic team to shape the future of digital consumer experiences in LATAM. Lead product strategy and execution for innovative e-commerce solutions, driving customer satisfaction and loyalty whi...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive technical oversight and leadership in Pipeline Safety Management Systems, ensuring compliance, risk management, and operational performance. Collaborate across departments to enhance safety init...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$90K - $110K *

Accelerate progress at driving revenue growth and expanding customer relationships through innovative supply chain solutions. Leverage consultative sales skills to identify opportunities and build las...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock potential by leading IT SOX compliance and enhancing global security culture. Balance technical auditing with advocacy, ensuring financial integrity and regulatory adherence while fostering a r...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$183K - $220K *

Lead strategic initiatives for Integrated Delivery Networks and health systems, optimizing patient access and formulary adoption. Build executive relationships and drive clinical integration to enhanc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $115K *

Champion consultative sales of Payments Solutions, driving client growth through strategic partnerships and effective cash flow management while adhering to company values and policies...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's redefining technology consulting by leading strategic initiatives, optimizing client environments, and mentoring IT staff. Leverage your expertise to enhance infrastructure and driv...

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$160K - $175K *

Elevate platform reliability by designing and evolving cloud infrastructure, CI/CD pipelines, and Kubernetes environments. Collaborate across teams to enhance software delivery, operational excellence...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$77K - $129K *

Lead your career with a pivotal role in technical claim-handling, overseeing investigations and negotiations for complex property claims. Mentor team members and support audits while ensuring complian...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Drive your career as a Compliance Architect, guiding clients through CMMC compliance journeys. Collaborate with stakeholders to assess risks, develop strategic roadmaps, and ensure alignment with regu...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$149K - $224K *

Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$135K - $160K *

Join a team that's redefining CRM platforms by architecting innovative, AI-driven solutions. This high-impact role requires visionary leadership to optimize data processing and enhance user experience...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring project execution aligns with strategic objectives. Drive process improvements and maintain client relationships while overse...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Optimize your skills in developing and maintaining SAS programs within a Mainframe environment. Take charge of code migration to cloud technologies and engage with stakeholders to create analytical so...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Advance your career by owning revenue accounting and assurance in a dynamic environment. Lead the development of policies, controls, and analytics while ensuring compliance with ASC 606 and preparing...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$150K - $180K *

Join a team that's shaping the future of AI by designing and implementing enterprise-grade solutions on Google Cloud and Azure, focusing on data migration, pipeline development, and robust cloud infra...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Join a team that's redefining power systems engineering by leading advanced studies in T&D, enhancing software tools, and fostering collaboration across projects to drive innovation and efficiency in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $170K *

Execute end-to-end digital onboarding of complex AI data center infrastructure, managing cross-functional teams to ensure timely delivery, stability, and optimization of high-performance systems for p...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Innovate solutions in power systems engineering by leading consulting initiatives, enhancing client relationships, and driving strategic growth in protection and control services while ensuring high-q...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$100K - $120K *

Lead the charge in managing clinical operations for dialysis services, ensuring quality patient care, compliance, and operational efficiency across multiple facilities while fostering strong relations...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.