Explore $100K+ Jobs in Kentucky

Find vetted professional opportunities paying $100,000 or more across Kentucky with Ladders. From Louisville and Lexington to growing communities throughout the state, explore roles for experienced professionals ready to take the next step in their careers. Browse openings across industries and compare opportunities that match your skills, experience, and goals.

Professional Opportunities Across Kentucky

Kentucky’s economy includes established sectors such as healthcare, manufacturing, logistics, finance, and technology, alongside growing businesses and regional employers. Opportunities vary by location and experience, with roles in corporate leadership, operations, sales, engineering, healthcare administration, and other professional fields. Review each listing for location, qualifications, compensation details, and work arrangement.

Find the Right Role for Your Experience

Use Ladders to focus your search on vetted jobs with salaries of at least $100,000. Explore positions by title, employer, location, or industry, and consider opportunities in major employment centers as well as other parts of Kentucky. Tailor your resume to each role and highlight measurable results, relevant expertise, and leadership experience.

Advance Your Career in Kentucky

Whether you are planning a career move within Kentucky or considering relocating to the state, compare openings and employer requirements to identify a strong fit. New listings and hiring needs can change, so check back regularly for current $100K+ professional opportunities.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,152

Sort By: Relevance

$80K - $95K *

Lead the provision and evaluation of patient care in a dynamic mental health setting, overseeing staff management and ensuring compliance with accreditation standards while driving performance improve...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$325K - $425K *

Unlock potential by driving cloud solutions sales in the public sector, cultivating strategic relationships, and exceeding revenue goals through innovative approaches and collaboration with internal a...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$111K - $152K *

Join a team that's redefining sales tools in HVAC. Drive strategy and execution for a next-gen sales portal, collaborating with cross-functional teams to enhance user experience and meet business goal...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$165K - $207K *

Lead strategic statistical initiatives for clinical development programs, ensuring rigorous study design and data analysis. Collaborate with cross-functional teams and regulatory authorities to drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape the future of business development by engaging inbound leads, assessing quality, and converting prospects into clients. Leverage your expertise in sustainability and aviation to drive growth and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Shape the future of indirect tax compliance and strategy. Collaborate across finance and with external partners to ensure compliance, mitigate risks, and drive operational success while managing audit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$88K - $105K *

Optimize environmental compliance and continuous improvement strategies at a manufacturing facility. Collaborate with stakeholders, manage regulatory requirements, and lead initiatives to ensure adher...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Transform business development and financial success by leading a dynamic team, managing resources, and driving strategic growth initiatives in a collaborative environment focused on excellence and in...

1 week ago

  •   8 - 10 years exp.  •   Staffing

$230K - $322K *

Grow your career with a leading ML team focused on enhancing ad retrieval systems. Drive technical direction, develop innovative models, and collaborate across teams to optimize user experience and ad...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$83K - $115K *

Transform service delivery by leading a skilled team of engineers, ensuring operational excellence and customer satisfaction through effective coordination and relationship management. Drive continuou...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $112K *

Drive the development and execution of a comprehensive enterprise risk management program, collaborating across global functions to enhance risk governance, reporting, and education while maintaining...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$132K - $272K *

Elevate retail partnerships by developing integrated strategies that drive growth and innovation. Collaborate across teams to transform complex opportunities into actionable plans, enhancing commerce...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$139K - $232K *

Unlock potential by providing enterprise architecture leadership for Retail and Consumer Banking. Shape technology strategies and roadmaps across various banking capabilities, ensuring alignment with...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Champion customer success by owning relationships, driving adoption, and ensuring renewals. Leverage deep trust to generate qualified leads while proactively engaging law firm accounts to enhance thei...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$88K - $105K *

Drive the execution of influencer marketing strategies, managing relationships with creators and overseeing performance metrics to maximize ROI. Lead a team while collaborating with cross-functional p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$200K *

Lead the charge in driving enterprise growth marketing strategies, optimizing pipeline performance, and orchestrating cross-functional initiatives to scale demand generation and revenue outcomes acros...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's focused on driving growth and customer satisfaction in the commercial and industrial sector. Leverage your sales expertise to manage accounts, resolve customer issues, and identify...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Help us manage diverse projects that drive strategic growth and collaboration across teams. As a key member of the EPMO, you'll ensure project success through effective stakeholder management and cont...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$116K - $171K *

Lead the charge in optimizing partner experiences and driving program modernization. This role requires strategic project management and a focus on automation to enhance the lifecycle of partnerships...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$145K - $175K *

Strategize and execute marketplace growth initiatives on Amazon and TikTok Shop, driving sales and profitability while managing P&L and aligning with omnichannel objectives. Lead operations, performan...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $125K *

Transform complex commercial casualty claims management by leveraging your expertise in construction-related exposures and litigation. Collaborate with a dedicated team to deliver exceptional outcomes...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Grow your career by managing our Energy and Sustainability Programs, driving continuous improvement in energy efficiency, overseeing project execution, and ensuring effective communication of savings...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Elevate patient care by leading advanced clinical pharmacy services, ensuring safe medication practices, and collaborating with healthcare teams to optimize therapeutic outcomes. Drive education and r...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Advance your career by managing large-scale government projects, ensuring compliance and quality control while supporting military education initiatives. Collaborate with teams to meet government stan...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$130K - $150K *

Drive growth and strategy for key telehealth categories by leveraging market insights, customer feedback, and cross-functional collaboration to enhance performance and deliver exceptional customer exp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • Where can I find jobs paying $100,000 or more in Kentucky?question toggle

    Browse Ladders for vetted professional openings in Kentucky with salaries of $100,000 or more. Search by job title, employer, industry, or location to narrow your options.

  • What types of high-paying professional jobs are available in Kentucky?question toggle

    Opportunities may include leadership, healthcare administration, manufacturing, logistics, finance, technology, sales, and engineering roles. Availability and qualifications vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Louisville and Lexington are major employment centers, and professional openings may also be available in other Kentucky communities. Check individual listings for the job location and work arrangement.

  • How can I improve my chances of getting a $100K+ job in Kentucky?question toggle

    Target roles that closely match your experience, tailor your resume to the job requirements, and emphasize measurable achievements, specialized expertise, and leadership impact.

  • Are all jobs listed in Kentucky remote or hybrid?question toggle

    Work arrangements vary by position and employer. Review each listing to see whether the role is onsite, hybrid, or remote.